阿奇霉素片

HPLC-MS/MS研究阿奇霉素片人体药动学

Pharmacokinetics Study of Azithromycin Tablets in Health Volunteers by HPLC-MS / MS

格列吡嗪胶囊剂的相对生物利用度和生物等效性评价阿奇霉素片的相对生物利用度和生物等效性

Relative bioavailability and bioequivalence of glipizide capsules Study on relative bioavailability and bioequiavailability assessment of Azithromycin tablets

方法：58例幽门螺杆菌感染性慢性胃病（男36例，女22例）餐前口服黄连素片共4周，同时餐前口服阿奇霉素片共1周；

Methods : 58 Cases ( M36 , F22 ) of helicobacter pylori infectious chronic gastropathy : Berberine tablets doses before each meal , for4 week ; and azithromycin tablets doses before each meal , for1 week ;

阿奇霉素肠溶片人体生物等效性研究兰索拉唑肠溶片的制备及稳定性考察

Bioequivalence of Azithromycin Enteric-coated Tablets in healthy volunteers Preparation and stability study of enteric coated lansoprazole tablets

结论阿奇霉素分散片的溶出度比普通片快。

Conclusion It is suggested that the dissolution of azithromycin dispersibles is better than that of azithromycin ordinary tablets .

研究几种新型崩解剂在阿奇霉素分散片中的作用，考察颗粒流动性、片剂崩解时限等质量控制指标，确定分散片中几种崩解剂的最佳用量。

These combined disintegrants were selected to obtain the best dosage of azithromycin dispersible tablets according to the fluidity of the granules and the disintegration of tablets .

小儿用阿奇霉素口腔崩解片的制备及质量控制

Preparation and Quality Control of Azithromycin Orally Disintegrating Tablets for Children 's Use

目的：建立高效液相-质谱法（HPLC-MS）测定人血浆中阿奇霉素的浓度，用于研究阿奇霉素片的人体药动学。

Objective : To develop a HPLC-MS method for determining azithromycin in human plasma , and to investigate pharmacokinetics of azithromycin in healthy volunteers .