氟康唑胶囊

HPLC-MS法评价氟康唑胶囊的人体生物等效性

Bioequivalence Assessment of Fluconazole Capsules in Human Plasma by HPLC-MS

国产和进口氟康唑胶囊剂的人体生物等效性研究

Bioequivalence of Domestic and Imported Fluconazole Capsules in Healthy Volunteers

各药代动力学参数无显著性差异（P>0.05）。试验制剂氟康唑胶囊相对生物利用度F为（104.3±8.5）%。

The relative bioavailability of the tested fluconazole was ( 104.3 ± 8.5 ) % .

2种氟康唑胶囊的主要药动学参数经交叉试验方差分析示无统计学差异（P均>0.05）。

Main pharmacokinetic parameters between test capsule and reference one showed no significant difference based on analysis of variance ( P > 0.05 ) .

对照2组单用用氟康唑胶囊首剂0.4g，以后每次0.2g，每日3次。

The control group 2 was used by fluconazole capsule ( 0.4 g for the first time , then 0.2 g for each time , 3 times a day );

治疗组给予每天口服氟康唑胶囊首剂0.4g，以后每次0.2g，每日3次，同时配合大蒜素注射液60mg加入5%葡萄糖500mL中静脉点滴，每日1次。

The treatment group was used by galic injection ( 60 mg galic injection + 5 % Glucose 500 mL iv drip , qd ) and fluconazole capsule ( 0.4 g for the first time , then 0.2 g for each time , 3 times a day );

国产氟康唑胶囊剂治疗深部真菌感染的多中心临床观察

A multiple center clinical trial on fluconazole for deep-seated fungal in-fections

氟康唑胶囊溶出试验数据处理方法比较

The Comparsion of Data Processing Methods for Fluconazole Capsule Dissolution Testing

目的：考核国产口服氟康唑胶囊的疗效和安全性。

OBJECTIVE : To study the efficacy and safety of fluconazole capsule .

口服氟康唑胶囊剂治疗肺部真菌病38例的临床观察

Fluconazole in the treatment of 38 patients with pulmonary mycoses

氟康唑胶囊和片剂溶出度考察

Determination of Dissolution of Fluconazole Capsules and Fluconazole Tablets

用高效液相色谱法测定氟康唑胶囊的溶出量

Determination of Quantity of Fluconazole Capsules Dissolution by HPLC

达克宁栓伍用氟康唑胶囊对外阴阴道念珠菌病临床疗效观察

Observation of clinical curative effect of vulvovaginal candidiasis treated with miconazole nitrate and fluconazole capsules

氟康唑胶囊健康志愿者的生物等效性研究

Bioequivalence of Fluconazole Capsule in Healthy Volunteers

目的研究氟康唑胶囊试验制剂与对照制剂的人体生物等效性，评价氟康唑在人体内的药动学。

OBJECTIVE To study the bioequivalence and pharmacokinetics of the test and the reference fluconazole capsule .

高效液相色谱法测定氟康唑胶囊的溶出度盐酸头孢他美酯片剂与胶囊剂体外溶出度比较

Comparison of Dissolution Rates of Cefetamet Pivoxil Hydrochloride Tablets and Its Capsules from 4 Manufacturers in vitro

氟康唑胶囊联合大蒜素注射液治疗慢性乙型重型肝炎合并真菌感染的疗效分析

Analysis of curative effect on treating with fluconazole capsule and galic injection for patients of chronic severe hepatitis B with fungal infections

结论：国产氟康唑胶囊治疗深部真菌感染的疗效、真菌清除率及安全性明显高于酮康唑。

CONCLUSIONS : Oral fluconazole is much safer and more effective in comparison with oral ketoconazole in treatment of deep seated fungal infections .

为观察国产氟康唑胶囊剂治疗深部真菌病的临床疗效与安全性，用国产氟康唑胶囊治疗深部真菌感染913例。

A multiple center clinical trial was conducted to evaluate the efficacy and safety of domestic fluconazole in treating 913 cases of deep-seated fungal infections .

采用转篮法对国产和进口氟康唑胶囊进行体外溶出度试验，求算威布尔分布函数。

In this paper , the dissolution testings on two kinds of Fluconazole capsules domestic and inport products were carried out with basket method , and the parameters of Weibull distribution function were obtained .

氟康唑（三维）胶囊的相对生物利用度为96%。

The relative bioavailability of the fluconazole capsule ( Sanwei ) was 96 % .