转录控制
- transcriptional control
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MTA1(Metastasis-associated1)蛋白是一种蛋白复合物,它具有组蛋白脱乙酰基酶的活性,在组蛋白的脱乙酰基,染色质重塑,转录控制的过程中具有重要作用。
MTAl ( Metastasis-associated 1 ) protein is a protein complex with histone deacetylase activity . It plays an important role in histone deacetylation , alteration of chromatin structure and transcriptional control .
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藉由清除基因调控区域上的短序列以进行转录控制。
Transcriptional control mediated by cleansing of short sequences from gene regulatory regions .
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PTI基因翻译起点上游具有‘TATA’和‘CCAAT’等转录控制元件,其包含的最大阅读框架能编码一个213aa的多肽。
The longest open reading frame in the PTI gene , which contains conventional ' TATA ' and ' CCAAT ' transcription control elements , potentially encode a peptide of 213 amino acids .
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植物对非生物胁迫的应答反应涉及到许多基因和生化分子机制,胁迫相关基因、蛋白质及代谢物构成了一个复杂的调控网络,其中转录控制具有举足轻重的作用。
Plant responses to abiotic stresses involve many genes and biochemical molecular mechanisms and stress-associated genes , proteins and metabolites form a complicated regulation network in which transcription control plays a balance-holding role .
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MEF-2和GEF可能参与对转录的控制。
MEF-2 and GEF may be involved in transcriptional control .
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科恩伯格在真核细胞转录调节控制分子机制方面的研究中取得了突破性进展。
On Mechanisms Kornberg has made breakthrough progress in the molecular understanding of the transcription and its regulation in eukaryotic cells .
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启动子是位于结构基因5′端上游区的调控序列,在转录水平控制着植物基因表达的时空性。
As a important regulatory element of 5 ' upstream regions of structure gene , promoter controls gene expression characteristic of space and time in transcriptional level .
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转录因子是控制基因表达第一阶段即DNA转录成RNA的一种蛋白质。它通过特异性结合调控区域的DNA序列来调控基因转录过程[1]。
Transcription factors ( TF ) are proteins that control the first step of gene expression , the transcription of DNA into RNA sequences , which regulate gene transcription by specific binding of the regulatory regions of DNA sequences .
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HAP是与CCAAT框结合的非常重要的一类转录因子,控制基因的表达,并广泛分布于酵母、哺乳动物、植物细胞中。
HAP , a kind of important transcription factor , occurs in yeasts , mammals and plants . It can bind to the CCAAT box and regulate the expression of target genes .
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Notch信号途径是通过局部细胞间相互作用,实现细胞间通讯、胞浆内的信号转导以及核内转录,从而控制细胞的增殖、分化、凋亡、迁移及粘附等细胞的命运的途径。
Notch signal pathway is an important mechanism to control the communication of cells and cells , signal transduction in the cytoplasm and transcription in the nuclear by the interactions of cells , then to determine cell proliferation , migration , growth , differentiation , and death .
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植物基因转录的组合控制
The combination control of plant gene transcription
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这些蛋白作为主要的转录调控因子,控制特异细胞的形成和有性形态的形成的途径。
These proteins control , as master regulatory transcription factors , pathways of cell speciation and sexual morphogenesis .
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基因的表达由一种叫转录因子的蛋白质控制,这种蛋白质本身也是通过基因的制造的。
The activity of genes is controlled by proteins called transcription factors that are , themselves , the products of genes .
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大量研究表明砷可以通过诱导信号转导通路,激活转录因子和改变控制细胞生长、增殖和恶性转化的基因表达来发挥促癌作用。
A number of evidences have shown that arsenic is of property to promote tumor by inducing intracellular signal transduction , activating transcription factors and changing the expression of genes that are involved in promoting cell growth , proliferation and malignant transformation .
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转录靶向设计,即在转录水平控制外源性基因的表达,限制基因在靶细胞中表达;
Transcriptional targeting , which does not change the tropism of virus but restricts gene expression to target cells ;
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到目前为止,许多免疫学家都以为免疫系统是在转录水平进行调控的,转录因子是控制基因的总开关。
Up to now , most immunologists have assumed the immune system was governed at the level of transcription factors , the master regulator proteins that control how genes are turned off and on .
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NF-κB是一种多极性基因调控性能的转录因子,能够激活若干个炎症反应、机体免疫反应及多种细胞因子的基因转录过程,从而控制它们的生物合成。
Nuclear factor kappa B ( NF - κ B ) has been recognized as an important transcription factor related to many immune and inflammatory responses . NF - κ B activates transcription of many cytokines and controls their biosynthesis .