角化不良

92例角化不良切片的光镜观察分析

Observation and analysis by microscopy in 92 cases of dyskeratosis

先天性角化不良6例

Six cases of dyskeratosis congenita

而角化不良细胞、透明小体很可能是AKautoAb作用于脱落角朊细胞的结果。

Dyskeratotic cells and hyaline corpuscles may be the results of interaction of the AK auto Ab of the exfoliative keratinocytes .

其他细胞是化生或非典型化生和角化不良或非典型角化不良细胞；应该是ASCUS的范畴。

Other cells are metaplastic or atypical metaplastic cells and parakerototic or atypical parakeratotic cells , should be in ASCUS category .

目的检测一例先天性角化不良（DKC）患者DKC1基因的突变情况。

Objective To detect the mutation in DKC1 gene in a patient with dyskeratosis congeni-ta .

目的研究先天性角化不良（DKC）一家系的基因突变情况和遗传方式。

Objective To identify the mutation of DKC1 gene and its inheritance in a pedigree with dyskeratosis congenita ( DKC ) .

先天性角化不良1例及家系调查

Dyskeratosis congenita : a case report and the family pedigree analysis

该先天性角化不良症网站也精心策划的良好环境美化和研究中心，连接通道的阴影，清楚地表明致力于环境管理和社会责任。

The DKC site is also well-planned with good landscaping and shaded walkways that connect the research centers , clearly demonstrating commitment to environmental stewardship and social responsibility .

结果先证者为3岁女孩，主要表现为皮肤脆性增加，受力部位易出现水疱及糜烂，并伴有头发短、稀，甲营养不良和掌跖角化等外胚层发育不良的表现。

Results The patient was a 3-year-old girl who presented increased skin fragility with trauma-induced , blisters and erosions , combined with short and sparse hair , finger-and toe-nail dystrophy and palmoplantar keratoderma .