薯蓣

酶催化-超临界CO2技术从穿山龙中萃取薯蓣皂甙元工艺

Enzymic catalysis and the supercritical CO_2 extraction diosgenin from dioscorea

超临界CO2萃取盾叶薯蓣醇提物中薯蓣皂素

Supercritical CO_2 Fluid Extract of Diosgenin from Dioscorea Zingiberensis

水解物pH近中性时，薯蓣皂甙元的得率最高；

When pH of substance is close to 7 , the extracting rate of diosgenin is maximal .

HPLC法测定金刚藤胶囊中薯蓣皂苷元的含量

Determination of the Content of Diosgenin by HPLC

方法用TLC法鉴别季德胜蛇药片中的薯蓣皂苷元。

Methods To identify diosgenin in Jidesheng antivenornous tablets by TLC .

方法：超临界CO2萃取技术提取，高效液相色谱法测定含量。结果：穿龙薯蓣根茎中花期薯蓣皂苷元含量最高为1。

Methods : We adopted SFE-CO2 technology to obtain diosgenin and determined the content of the diosgenin through HPLC .

结论II为首次从穿龙薯蓣中分离得到的新化合物，命名为穿龙薯蓣皂苷Dc。

CONCLUSION Compound II is a new steroidal saponin and firstly isolated from Dioscorea nipponica Makino . It was named as dioscin Dc .

菊叶薯蓣叶片叶绿素a的含量明显高于叶绿素b，二者之间具体比例关系还需进一步研究。

Chrysanthemum leaves of chlorophyll content of diosgenin a significantly is higher than the chlorophyll b , and the specific scale relation between them still need further research . 2 .

薯蓣皂苷元诱导人白血病细胞（HL-60）分化及凋亡研究

Studies on Differentiation and Apoptosis of the Human Leukemia Cell Line Induced by Diosgenin

山药及盾叶薯蓣对家蚕寿命和小鼠LPO、LF的影响

Effects of Dioscorea opposita and Dioscorea zingiberensis on age of silkworms and lpo , lf of mice

结果：常规提取法薯蓣皂苷元产率为0.622%，超临界CO2萃取法薯蓣皂苷元产率为1.226%。

Results : The yield rate of diosgenin by SFE-CO_2 technology was 1.226 % , while that of traditional solvent extraction was 0.622 % .

植物外源激素6-BA和IAA可以从盾叶薯蓣雄株上诱导出雌花；

Plant external hormone 6-BA and IAA may induce the female flower from the Dioscorea zingiberensis male plant ;

对盾叶薯蓣水提多糖WEP的提取工艺过程进行了优化。

The extraction process of WEP from D. zingiberensis were optimized .

薯蓣皂苷能够使Ox-LDL诱导的血管内皮细胞凋亡率降低，且呈一定的浓度依赖性。

Dioscin against BAECs apoptosis in Ox-LDL model , and present concentration dependent . 3 .

盾叶薯蓣（Dioscoreazingiberensis）组织培养研究初报

Preliminary report on tissue culture of Dioscorea zingiberensis

酶解法转化人参皂苷Rh1及其含量测定栽培盾叶薯蓣中皂甙元含量与质量的动态变化

Determination and enzymolysis preparation of ginsenoside Rh_1 THE DYNAMIC CHANGES ON THE DIOSGENIN CONTENT AND QUALITY OF THE CULTIVATED DIOSCOREA ZINGIBERENSIS WRIGHT

薯蓣有效组分MPD治疗冠心病的基础研究

The Basic Study of MPD 's Effects on Coronary Artery Disease

薯蓣皂苷元在5.12μg～25.6μg范围内线性关系良好，样品平均加样回收率为97.5%。萆薢提取物中总皂苷含量为53.1%。

The linear relationship of diosgenin was better between 5.12 μ g ~ 25.6 μ g , average recovery rate was 97.5 % and the content of total saponin was Dioscorea 53.1 % .

背景与目的：我们从福州薯蓣的根茎中首次分离得到薯蓣皂苷的次皂苷元B（P.B），并发现P。

BACKGROUND & OBJECTIVE : The authors have isolated prosapogenin B of dioscin ( P.B ) newly from Dioscorea futschauensis R.

通过细胞表面分化抗原CD11b，CD14测定，薯蓣皂苷元主要是诱导HL-60细胞向粒系分化。

It wat found that diosgenin-treated HL-60 cells differentiated mainly along the granulocytic lineage , as judged by analysis of cell-surface antigens .

甘薯、薯蓣和魔芋叶片SPAD值与叶绿素含量的相关性研究

Study on Correlations Between SPAD readings and Chlorophyll Content in Leaves of Sweet Potato , Dioscorea and Konjaku

用随机扩增多态DNA标记（RAPD）技术对华中农业大学薯蓣资源圃中收集的11个盾叶薯蓣居群及4个薯蓣属植物居群的混合样品进行了遗传多样性的检测。

Random amplified polymorphic DNA ( RAPD ) were applied to detect genetic diversity of bulking samples of 11 Dioscorea zingiberensis populations and 4 other Dioscorea populations from Dioscorea resources plot of Huazhong Agricultural University .

方法：以薯蓣皂甙元的含量为指标，应用L9（34）正交试验设计筛选穿龙薯蓣总皂甙水解条件。

Methods : The optimum hydrolysis conditions were investigated by the orthogonal design and in diosgenin content as a marker .

薯蓣皂苷元，这种植物甾体，有可能成为白血病的潜在的诱导分化剂，但我们还需要进一步研究薯蓣皂苷元诱导HL-60细胞分化的具体分子机制。

The plant steroid , diosgenin may be a potent inducer of differentiation of leukemic cells . We need to study the mechanism of diosgenin-induced HL-60 cell differentiation .

方法：采用HPLC-MS分析对大鼠口服麦冬皂苷肠溶微球的代谢产物之一薯蓣皂苷元进行体内过程的监测。

METHODS : HPLC-MS method of determining rat 's metabolite diosgenin in vivo was established after single-dose oral Ophiopogon japonicus saponin enteric microsphere .

50日龄Wistar大鼠每日皮下注射D－半乳糖48mg／kg，连续40日，造成亚急性衰老模型，在注射D－半乳糖的同时，给予加减薯蓣丸口服。

Abstract Wistar rats of fifty days old were subcutaneously injected with D-galactose 48mg / kg daily for 40 days . To make subacute ageing model .

目的：研究薯蓣皂苷元（Diosgenin，Dio）对替加氟（FT-207）抗肿瘤的增效减毒作用。

AIM : To observe the effects of diosgenin on enhancing efficacy and reducing toxicity of FT-207 in tumor-bearing mice .

薯蓣皂苷元（Diosgenin）是合成多种甾体激素类药物和甾体避孕药的理想前体，占甾体激素类药物原料的60%。

Diosgenin is an important precursor in the synthesis of steroidal hormones and steroidal contraceptives , and about 60 % steroidal hormone medicines are produced from it .

目的观察薯蓣皂苷元（Diosgenin，Dio）对人胃低分化粘液腺癌（MGC-803）细胞的作用，并初步探讨其作用机制。

Objective To observe the effect of diosgenin ( Dio ) on poor differentiated adenocarcinoma ( MGC-803 ) cells of human stomach and discuss the mechanism .

薯蓣皂苷元对人骨肉瘤U-20S细胞增殖和周期的影响

Effect of Diosgenin on Proliferation and Cycle of Human Osteosarcoma U-20S Cell Line