荔枝核

荔枝核抑制乳腺增生大鼠乳腺组织ER和PR表达及促进细胞凋亡作用

Effects of litchi seed on mammary tissue for inhibiting expression of estradiol and progestogen receptor and expediting apoptosis in rat with hyperplasia of mammary glands

荔枝核增强2型糖尿病-胰岛素抵抗大鼠胰岛素敏感性作用

Effects of Litchi seed on enhancing insulin sensitivity in type 2 diabetic-insulin resistant rats

荔枝核提取液和二甲双胍两者间改善IR作用无显著性差异（P＞0.05）。

There was not obvious difference between Semen Litchi abstract and Metformin in improving insulin resistance ( P0.05 ) .

6采用GC-MS技术对荔枝核中的挥发性成分进行了研究。

The component of volatile material was studied by GC-MS method .

【结果】（1）荔枝核、菊花、天麻、天花粉煎煮液灌胃给药后均可显著提高胰岛素敏感性指数（P＜0.01），改善IR；

Results 1 . Fluids of Semen Litchi , Flos Chrysanthemi , Rhizoma Gastrodiae and Radix Trichosanthis could greatly raise ISI ( P0.05 ) and improve insulin resistance .

荔枝核主要含酸性化合物，挥发油，碳水化合物等化学成分，其主要药效有降血糖、调血脂、抑制乙型肝炎病毒表面抗原（HBsAg）等；

Semen litchi is mainly composed of acidic compounds , volatile oil and carbohydrates , its main pharmacologic activities are to decrease FBG and TC and restrain HBsAg .

目的：研究荔枝核水提取物（waterextractfromSemenLitchi，以下简称荔枝核）改善2型糖尿病大鼠（T2DM）胰岛素抵抗（IR）的药理学机制。

Objective : To investigate the pharmacological mechanism of Semen Litchi water extract ( SL ) on enhancing insulin sensitivity in type 2 diabetic rats ( T2DR ) with insulin resistance ( IR ) .

研究了荔枝核提取液对亚硝胺（NDMA）合成的阻断作用及对亚硝酸根离子的清除作用。

The two functions of litchi core extraction were studied in this paper : to interdict the synthesizing of NDMA and to eliminate nitrite .

采用荔枝核提取液和二甲双胍治疗IR患者，4周后观察空腹血糖、口服葡萄糖耐量试验（OGTT）后2小时的血糖、血清胰岛素及胰岛素敏感性指数等指标的影响。

FBG , 2-hours blood glucose ( 2hBG ) after oral glucose tolerance test ( OGTT ), serum insulin and ISI were detected 4 weeks after Semen Litchi abstract and Metformin were given to patients with insulin resistance .

结果动物实验表明，在给予450mg／kg／d的剂量下，荔枝核各部位降血糖活性不明显，与对照组比较无统计学意义；

Results At the dosage of 450mg / kg / d for 30 days , the three parts of seed of Litchi chinensis Sonn . have not showed significant effect on serum glucose .

结果荔枝核粗皂甙对正常和糖尿病小鼠的降糖率分别为16.74%和59.57%，其降糖效力与正常组、模型组及优降糖组比较均有显著性差异（P0.05或0.01）。

Results The hypoglycemic rate of the saponin on the normal and diabetic mice were 16.74 % and 59.57 % respectively . The hypoglycemic activity was stronger in the experimental group than that in the normal control group , negative control group and dimethyldiguanide group ( P0.05,0.01 ) .

采用反复的硅胶柱层析、SephadexLH-20等分离纯化手段，对荔枝核有效部位进行分离。并运用波谱学方法对其进行结构鉴定。

The repeated Silica gel column chromatography and Sephadex LH-20 etc. methods were used to separate and purify the compounds , and the spectroscopy method was used to identify the structures of the chemical compounds .

荔枝核粗皂甙降血糖作用的实验研究

Study on the hypoglycemic activity of saponin extracted from litchi seed

荔枝核活性成分分析及其提取物抗氧化性能研究

Antioxidant Capacity and Preliminary Active Components Study of Litchi Seed Extract

荔枝核抗乙肝病毒有效部位的化学成分研究

Study on the Chemical Compositions of Anti-HBV Part in Semen Litchi

荔枝核淀粉提取工艺及其性质的研究

Studies on Extraction Process and Properties of Starch from Lichee Stone

这两个化合物均从荔枝核中首次分离得到，其中原花色素-A1是从该属植物中首次得到。

Proanthocyanidin-A1 is the first compound separated from species of Litchi .

荔枝核中黄烷-3-醇的鉴定及原花青素的提取

Identification of flavan-3-ol and extraction of Procyanidins from Litchi chinensis Sonn

荔枝核中含有的丰富的多酚类物质可能是其发挥抗病毒功能的有效成分之一。

These plenty of polyphenol maybe the active components that anti virus .

荔枝核黄酮类化合物的提取工艺研究

Study on extraction process of flavonoids from Litchi seed

荔枝核的化学成分研究

Studies on chemical constituents in seed of Litchi chinensis

荔枝核药用及荔枝种贮藏研究进展

Advances in the Studies on the Pharmacologic Activities and Storages of Semen Litchi

荔枝核颗粒治疗慢性乙型肝炎的疗效观察

Observation on Treatment of Chronic Hepatitis B with Particles of Lychee Nut Stone

以荔枝核为原料，提取了其中的淀粉，并对其进行了纯化。

The extraction and purification process of starch from lichee stone were studied .

荔枝核总皂甙的含量测定

Estimation of content on total saponins from semen litchi

荔枝核皂苷改善地塞米松致大鼠胰岛素抵抗作用机制研究

Studies on Mechanism of Saponin of Litchi in Reversing Dexamethasone-induced Insulin Resistance in Rats

测定荔枝核抗乙肝成分黄酮类化合物含量为7.13%。

The content of anti-hepatitis B consituents flavonoids in Litchi Seed was 7.13 % .

正交试验优选荔枝核总皂苷提取工艺

Optimization of the Extraction Technology of Total Saponins from Litchi chinensis by Orthogonal Experiment

中药荔枝核的挥发油鉴定

Identification of Essential Oil from Semen Litchi

荔枝核拮抗2型糖尿病大鼠胰岛素抵抗作用的药理学机制

Pharmacological Mechanism of Semen Litchi on Antagonizing Insulin Resistance in Rats with Type 2 Diabetes