在代谢工程改造氨基酸合成途径形成异丁醇的策略中，亮氨酸合成途径的α-异丙基苹果酸合酶（a-IPMS）尤为重要。
During engineering amino acid synthesis to produce isobutanol , a-isopropylmalate synthase ( a-IPMS ), which is used in pathway of leucine biosynthesis , is especially important .
苹果酸合酶