膀胱灌注

LAK细胞和IL-2联合应用膀胱灌注预防肿瘤复发的临床观察

Clinical Observation on the Effect of Bladder Irrigation with LAK Cell and IL-2 for Preventing Postoperative Recurrence of Bladder Cancer

术后常规化疗药物膀胱灌注。

Routine bladder irrigation was performed in all patients .

体外膀胱灌注噻替哌和丝裂霉素C的药效学研究

A pharmacodynamic study of thiotepa and mitomycin C on human bladder cancer cell line in vitro

磁场定位下磁化丝裂霉素C膀胱灌注预防膀胱肿瘤复发

Intravesical instillation of magnetic mitomycin C in the magnetic field for the prevention of recurrence of bladder tumor

目的通过膀胱灌注N蛳甲基亚硝基脲（MNU）诱导近交系大鼠膀胱肿瘤。

Objective To establish the model of bladder tumors in inbred line rats by N-methyl-N-nitrosourea ( MNU ) intravesically .

结论0.5%碘伏膀胱灌注可安全有效地治疗IC。

Conclusions Intravesical instillation with 0.5 % povidone-iodine is a safe and effective method for treatment of IC .

二组术后均常规行卡介苗（BCG）膀胱灌注。

Both groups received a bcg vaccine ( BCG ) routine treatment .

BCG和IL－2膀胱灌注预防膀胱癌复发的疗效观察

BCG and IL-2 intravesical instillation in the prevention of postoperative recurrence of bladder tumor

目的：探讨粘膜粘附缓释剂羟丙基纤维素（HPC）与丝裂霉素C（MMC）联合膀胱灌注对MMC在膀胱中保留的效果。

Purpose : To study the effect of mitomycin-c retention in urinary bladder by intravesical instillation of HPC-MMC .

目的：观察磁化丝裂霉素C（MMC）和磁场在膀胱灌注预防膀胱癌术后复发中的作用。

Purpose : To study the clinic effects of magnetic MMC agent in the magnetic field for prevention of postoperative bladder tumour recurrence .

目的探讨0.5%碘伏膀胱灌注治疗间质性膀胱炎（IC）的疗效、安全性及副作用。

Objective To evaluate the efficacy , safety and side effects of 0.5 % povidone-iodine in intravesical treatment of interstitial cystitis ( IC ) .

结论HCPT、MMC、DDP膀胱灌注化疗均能达到降低肿瘤复发的疗效。

Conclusions HCPT , MMC and DDP have the similar efficacy for preventing postoperative recurrence of bladder cancer .

目的观察丝裂霉素C（MMC）和白介素2（IL2）联合BCG交替膀胱灌注预防膀胱癌术后复发的疗效。

Objective To evaluate the alternate intravesical instillation of MMC and IL 2 together with BCG for the prevention of bladder cancer recurrence .

目前公认丝裂霉素C（MMC）是膀胱灌注化疗最为常用，且效果较好的化疗药物之一。

At present it is generally acknowledged that MMC is the most commonly used in bladder transfusion chemotherapy and is one of the chemotherapeutic drugs that can get better effect .

治疗采用经尿道电切和术后丝裂霉素C膀胱灌注。结果30例经624个月随访，25例治愈（83·33%），余5例中3例次电切治愈，1例发展为腺癌。

Results Among 30 cases followed up for 6 to 24 months , 25 cases ( 83.33 % ) were healing well , 3 patients obtained curing through secondary resection , two cases finally developed into adenocarcinoma of bladder .

TURBt及术后膀胱灌注N&CWS治疗膀胱表浅肿瘤

Treatment of superficial bladder tumor after TURBt plus intravesical therapy with N-CWS

目的：观察卡介苗（BCG）膀胱灌注后尿液中IL－2、TNF含量与临床预后的关系。

Objective : To explore the relationship between the levels of urinary IL 2 and TNF and prognosis after intravesical BCG instillation in patients with superficial bladder carcinoma .

结论BCG膀胱灌注可引起血浆内毒素水平升高，这可能与BCG不良反应发生有关。

Conclusion The result suggested that BCG instillation could elevate the endotoxin concentration of plasma and might be responsible for side effects during intravesical BCG instillation .

目的探讨卡介苗（BCG）加α干扰素（αIFN）膀胱灌注预防膀胱癌术后复发的疗效。

Objective To evaluate the therapeutic efficacy of BCG ( bacillus calmette guerin ) combined α IFN ( interferon ) for the prevention of postoperative recurrence of bladder cancer .

因憩室癌恶性程度高，预后差，术后需辅以BCG、IL-2膀胱灌注治疗。

Because of carcinoma of vesical diverticulum has higher malignancy and poor prognosis , the bacille Calmette , Guerin and Interleukin 2 should be needed as postoperative adjuvant treatment .

目的用Meta分析比较吡柔比星（THP）、丝裂霉素C（MMC）膀胱灌注预防膀胱癌术后复发的疗效观察与毒性。

Objective To compare the prophylactic efficacy and toxicity of intravesical pirarubicin ( THP ) with mitomycin C ( MMC ) on recurrence of Chinese bladder cancer using a Meta-analysis .

结论：BCG膀胱灌注可减少上尿路移行细胞癌局部复发，提高5年生存率。

Conclusion BCG perfusion into the urinary bladder can decrease the local recurrence of transitional cell carcinoma in upper ureter , and can enhance the five year livability .

目的：观察卡介苗加白介素-2（IL-2）膀胱灌注治疗膀胱移行细胞癌的疗效。

Objective : To observe the curative effect of bacillus Calmette-Guerin ( BCG ) plus interleukin-2 ( IL-2 ) for treating vesical transitional cell carcinoma ( TCC ) by intravesical perfusion .

结论沙培林膀胱灌注能够显著降低患者血液中VEGF水平，是一种有效的杀死膀胱肿瘤细胞的方法。

Conclusion Perfusion of bladder of sapylin can obviously decrease the level of VEGF in blood . So , it is an effective method to kill the cells of superficial bladder transitional cell carcinoma .

研究表明在BTCC患者的膀胱灌注液中MMP-9有71%以酶原表达，且表达强度同肿瘤的分级、分期相关。

A recent study demonstrates there is about 71 percent MMP - 9 enzyme precursor analysis in the perfusion fluid of bladder in BTCC patients .

结果：经尿道膀胱灌注HSVtk基因后48h，RT-PCR检测出膀胱肿瘤中HSVtk基因表达。

Results : Forty-eight hours after intravesical instillation of HSVtk gene , RT-PCR analysis of rat bladder tumors demonstrated the expression of HSVtk .

CIK细胞回输联合沙培林膀胱灌注预防表浅膀胱癌术后复发

Cytokine induced killer ( CIK ) cells infusion combination with intravesical instillation of OK-432 in the prophylaxis of local recurrence after resection of bladder cancer

结论TUR术后即刻膀胱灌注MMC加小剂量BCG维持预防浅表性膀胱癌术后复发疗效较好，不良反应少，临床使用安全可靠。

Conclusion Intravesical instillation of MMC immediately after TUR added with low dose BCG maintenance therapy is effective to prevent patients with superficial bladder cancer from recurrence .

方法检索国内外已公开发表的关于THP与MMC膀胱灌注治疗人膀胱癌复发的比较性研究资料，对纳入研究的资料进行统计学综合（Meta分析）。

Methods We retrieved published comparative studies on intravesical THP versus MMC for bladder cancer of Chinese people , and pooled the data from eligible studies ( Meta-analysis ) .

结果：联合膀胱灌注组的TNF和IL2受体水平显著高于吡柔比星组（P<0.01）。

Results : Levels of TNF and IL 2 receptor were found to increase significantly after combined instillation of pirarubicin and IL 2 ( P < 0.01 ) .