肾上腺增生
- 网络adrenal hyperplasia;CAH;Hyperplasia of Adrenal
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肾上腺增生的CT诊断(附66例分析)
Diagnosis of adrenal hyperplasia by multi-detector CT ( with an analysis of 66 cases )
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背景与目的:先天性肾上腺增生症(congenitaladrenalhyperplasia,CAH)是一组常染色体隐形遗传疾病,是最常见的遗传性内分泌疾病之一。
Background and purpose : Congenital adrenal hyperplasia ( CAH ) is a group of autosomal recessive disorder . It is one of the commonest genetic endocrinological diseases .
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治疗一些类型的先天性肾上腺增生性肥大能够运用诸如羊水诊断或绒毛膜取样的产前检查被发现。
Treatment some forms of CAH can be detected in prenatal tests like amniocentesis or villus sampling .
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结论CT是发现和诊断肾上腺增生性疾病的有效检查方法。
Conclusion CT is effective in detection and diagnosis of adrenal gland hyperplastic diseases .
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与手术病理比较,B超在醛固酮腺瘤和双侧肾上腺增生中的诊断符合率分为95.77%及73.33%;CT为98.51%及31.03%;
The coincidence of ultrasonography was 95.77 % and 73.33 % in APA and BAH , 98.51 % and 31.03 % with CT .
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ACTH非依赖性大结节样肾上腺增生(附三例报告)
Corticotropin ( ACTH ) independent macronodular adrenal hyperplasia ( report of 3 cases )
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B超与CT相比对肾上腺增生性疾病的检出率有显著性差异(P0.001)。
There was significant difference between CT and brightness mode ultrasonic examination in diagnosis of adrenal gland hyperplastic diseases ( P 0.001 ) .
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16例经手术治疗,其中15例病理证实为醛固酮腺瘤(APA),1例病理证实为原发性肾上腺增生(PAH)。
16 cases of PA were confirmed by pathological examination after operation , including 15 cases of aldosterone-producing adenoma ( APA ) and 1 case of primary adrenal hyperplasia ( PAH ) .
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目的探讨ACTH非依赖性大结节样肾上腺增生(AIMAH)的临床病理特点。
Objectives To study the clinical presentation , laboratory findings , and pathologic characteristics of patients with corticotropin ( ACTH ) independent macronodular adrenal hyperplasia ( AIMAH ) .
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肾上腺增生性高血压38例临床分析
A Clinical Analysis of 38 Cases of Adrenal Hyperplastic Hypertension
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不同表型先天性肾上腺增生症患儿的出生身长和体重
Birth length and weight in congenital adrenal hyperplasia according to the different phenotypes
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先天性肾上腺增生症&11β-羟化酶缺乏症的分子遗传学研究进展
Progress in molecular-genetic researches on congenital adrenal hyperplasia & 11 β - hydroxylase deficiency
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先天性类脂质性肾上腺增生症分子遗传学分析
Molecular genetic analysis of congenital lipoid adrenal hyperplasia
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高效液相色谱法在先天性肾上腺增生症诊断和分型中的应用
The application of high-performance liquid chromatography to the diagnosis and classification of congenital adrenal hyperplasia
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双方都携带有先天性肾上腺增生性肥大基因的父母会将基因遗传给后代。
Parents who are both carriers of the CAH trait can transmit it to their children .
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而先天性肾上腺增生症通常在每15000个婴儿中的一人身上发生,这种疾病将导致男性体征过早出现或不适当地出现。
Congenital adrenal hyperplasia affects one in around 15,000 births and causes male characteristics to appear early or inappropriately .
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过去,患有先天性肾上腺增生性肥大的患者及其家人常常感到孤立无助,也发现难以获得更多的有关病症知识。
In the past , persons with CAH and their families often felt isolated and found it difficult to learn more about the condition .
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结果45例中醛固酮瘤15例,误诊的双侧肾上腺增生3例,嗜铬细胞瘤8例,腺瘤、腺癌型皮质醇增多症4例和意外瘤15例。
Results Of 45 cases , 15 were with aldosterone producing adenoma ( APA ), 3 with of BAH , 8 pheochromocytoma , 4 adrenal tumor with hypercortisolism and 15 adrenal incidentaloma .
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结果:(1)在533例高血压患者中,伴肾上腺增生的58例,占受检人群10.88%。44例伴左侧肾上腺增生(75.86%),14例伴双侧肾上腺增生(24.14%)。
Results : ( 1 ) There were 58 hypertensives with adrenal hyperplasis in 533 patients including 44 in left adrenal ( 75.86 % ) and 14 in both adrenal ( 24.14 % ) .
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目的:肾上腺髓质增生(AdrenalMedullaHyperplasia,AMH)是近30年来逐渐被人们认识的一种少见疾病,临床表现为以高血压为主的综合症。
Objective : Adrenal Medulla Hyperplasia ( AMH ) is the rare disease in recent 30 years .
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肾上腺皮质增生症患者肾上腺皮质组织ACTH的表达与血浆ACTH的关系
Relationship between ACTH expression in adrenal cortical tissue and plasma ACTH level in patients with adrenal cortical hyperplasia
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目的提高对肾上腺髓质增生症(AMH)的诊断与治疗水平。
Objective To study the diagnosis and treatment of adrenal medullary hyperplasia ( AMH ) .
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用放免法检测肾上腺皮质增生症患者血浆ACTH的浓度,并与肾上腺皮质组织中局部表达ACTH的水平进行相关性分析。
The correlation between plasma ACTH concentration and expression level of ACTH in adrenal cortical tissue of patients with adrenal cortical hyperplasia was studied .
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目的:建立大鼠肾上腺髓质增生(AMH)模型。
Objective : To establish a rat experimental model of adrenal medulla hyperplasia ( AMH ) .
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目的:探讨酪氨酸羟化酶(TH)蛋白在肾上腺髓质增生(AMH)大鼠肾上腺组织中的表达与肾上腺髓质增生的关系。
Objective : To study the relationship between the expression of tyrosine hydroxylase ( TH ) in adrenals and adrenal medulla hyperplasia ( AMH ) in rats .
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目的提高对迟发型先天性肾上腺皮质增生(CAH)合并睾丸结节的认识和早期诊治水平。
Objective : To improve the knowledge and early diagnosis of late-onset congenital adrenal hyperplasia ( CAH , CYP21D ) combined testis tubercle .
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肾上腺髓质增生患者均有高血压,24h尿VMA均增高,大部分(15/16)患者尿儿茶酚胺高于正常;
In AMH group , all the patients were hypertensive and their 24 h urinary VMA was increased . Most of them ( 15 / 16 ) had higher urinary catecholamine level than normal ;
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结果ACTH非依赖性肾上腺皮质增生症皮质组织的ACTH表达水平,明显高于ACTH依赖性肾上腺皮质增生症皮质组织和正常肾上腺皮质组织(均P<0.05);
Results The expression of ACTH was significantly higher in adrenal cortical tissue of patients with ACTH-independent adrenal cortical hyperplasia than those with ACTH-dependent adrenal cortical hyperplasia and normal adrenocortical tissue ( both P < 0.05 ) .
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结论细胞凋亡调控基因参与了肾上腺髓质增生的病理过程。在此调控网络中,bcl-2基因发挥了较为重要的作用,bax基因的表达减少。
Conclusion Abnormal expression and regulation of apoptosis-regulatory genes play important roles in the development and progression of adrenal medulla hyperplasia , in which bcl-2 gene may take a larger part during the pathologic process and bax gene expression is restained in this meshwork .
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目的探讨原发性肾上腺髓质增生症(PAMH)的诊断方法和治疗原则。
Objective To investigate the diagnosis and treatment of primary adrenal medullar hyperplasia ( PAMH ) .