淋巴细胞减少

结论CRF时外周血淋巴细胞减少表明CRF患者体内存在免疫缺陷；

Conclusion Lymphopenia in the peripheral blood from the CRF patients shows immunodeficiency ;

CD4细胞的自身免疫可导致持续性的淋巴细胞减少症。

Autoimmunity to CD4 T-cells may account for the persistence of the CD4 T-cell lymphopenia in such cases .

播散性Kaposi肉瘤伴特发性CD4+淋巴细胞减少症及低剂量类固醇治疗

Disseminated Kaposi 's sarcoma associated with idiopathic CD4 + lymphocytopenia and low dose steroid therapy

目的阐明向免疫重建的淋巴细胞减少小鼠（reconstitutedlymphopenicmice，RLM）进行瘤苗免疫增强抗肿瘤免疫反应的机制。

Objective To explore mechanisms of the augmented anti-tumor immunity observed in reconstituted lymphopenic mice ( RLM ) receiving melanoma vaccination .

目的：探讨CD95表达在狼疮性肾炎（LN）患者CD4+淋巴细胞减少中所起的作用。

OBJECTIVE To investigate the effect of Fas receptor ( CD95 ) expression on reduction of CD4 + cells in patients with lupus nephritis .

结果急性心肌梗死胸痛发生后12h内相对淋巴细胞减少的敏感性最高（613%）；

Results The relative lymphopenia in 12 hours after onset of chest pain has the highest correlation with AMI , that is 61 3 % .

贫血和淋巴细胞减少与DQA10102正相关；

Anemia and lymphocytopenia respectively positively with DQA10102 ;

呼吸道及皮肤粘膜是本组SLE患者最常见感染部位；感染组较非感染组，平均住院日、SLEDAI、白细胞/淋巴细胞减少、尿蛋白水平、补体C3水平和1年死亡率差异显著；

There was significant difference in mean hospital time , SLEDAI , leukopenia / lymphopenia , 24h urine protein level , complement C3 level and one year death rate between infected SLE patients and control ones .

以淋巴细胞减少症和发育缓迟为临床表现的嘌呤核苷磷酸化酶缺陷（PNPdef）1例：经脐带血移植得以成功治疗

Purine nucleoside phosphorylase deficiency ( PNPdef ) presenting with lymphopenia and developmental delay : Successful correction with umbilical cord blood transplantation

小鼠淋巴细胞减少症模型的建立及其免疫学意义

Establishment of a mouse lymphopenia model and its immune characteristics

特发性CD4~+T淋巴细胞减少症伴播散性皮肤隐球菌病

Idiopathic CD4 ~ + T lymphocytopenia in a patient with disseminated skin cryptococcosis

目的分析特发性CD4+T淋巴细胞减少症的临床特点，并探讨其发病机制和治疗。

Objectives To explore the clinical features and treatment of idiopathic CD4 + T-lymphocytopenia .

淋巴细胞减少状态下的肿瘤免疫格局改变及其意义

Changed pattern of tumor immunity under lymphopenia setting and its significance in cancer biotherapy

目的：以放射线处理建立小鼠淋巴细胞减少症模型并探讨其免疫学意义。

Objective : To establish a mouse lymphopenia model via irradiation and to study its immune characteristics .

放疗或化疗诱导淋巴细胞减少联合免疫重建和瘤苗免疫

New strategy of cancer immunotherapy : irradiation or chemotherapeutics-induced lymphopenia combined with immune reconstitution and tumor vaccine

末梢血检查，白细胞总数正常，或淋巴细胞减少，单核细胞增加。

Peripheral blood examination , the total number of normal leukocytes , or lymphocytes decreased monocyte increase .

血清抗神经原抗体与淋巴细胞减少有关，用淋巴细胞吸收试验证明该抗体可与淋巴细胞交叉反应。

Antineuronal antibodies of blood were related to lymphocytopenia . Absorption test showed cross reaction between antineuronal antibodies and lymphocytes .

结论：以放射线处理成功建立淋巴细胞减少症模型，并具有增强免疫保护的效应。

Conclusion : Lymphopenia mouse model is successfully established and an enhanced immune protection can be induced under the lymphopenia status .

主要为胸腺萎缩，脾和淋巴结（肠系膜）的胸腺依赖区萎缩及其中淋巴细胞减少；

Decrease of lymphocytes in these areas , decrease or disappearance of lymphocytes in marginal zone of the spleen , and atrophy of follicles in the spleen and lymph node .

与之相比，未感染的淋巴细胞减少的小鼠的T细胞，对自身抗原经历急性动态平衡增殖，这些蛋白质呈弥散性分布。

By contrast , T cells from uninfected lymphopenic mice , in which T cells undergo acute homeostatic proliferation in response to self antigen , had a diffuse distribution of these proteins .

病理切片显示心、肺、胰腺等出现炎性细胞浸润，肺、胰腺、胸腺、法氏囊、脾脏、肝脏等有出血、淋巴细胞减少、坏死、崩解等变化。

Pathology showed heart , lung and pancreas appeared inflammatory cell infiltration , and lung , pancreas , thymus , bursa , spleen , liver showed hemorrhage , lymphocytes decreased , necrosis and / or collapse .

结果表明锰可使骨髓微核率升高，淋巴细胞减少，微量元素铁、锌、铜等也有所改变。

The results revealed that the manganese increased the micronucleus rate of bone marrow , decreased the lymphocyte counts , and gave rise to changes of trace elements such as Fe , Zn , and Cu in serum .

结果各组在麻醉手术后4h及术后1d白细胞总数、嗜中性分叶状粒细胞数显著增加（P＜0.05），淋巴细胞数减少；

Results White blood cell and neutrophil counts in every group increased at 4h after operation and at the 1st day after operation ( P < 0.05 ) , meanwhile lymphocytes decresed .

经FK506治疗后，肝移植患者的CD4+T淋巴细胞逐渐减少，CD8+T淋巴细胞逐渐增加，并恢复至健康对照组水平（P>0.05）。

After FK506 treatment , the CD4 ~ + T lymphocytes of the recipients were decreased gradually , CD8 ~ + T lymphocytes increased gradually , and went back to health-control level ( P > 0.05 ) .

另外，PFOA暴露同样可造成RD组小鼠体重显著下降，脾脏和胸腺严重萎缩，血液中淋巴细胞数量减少。

After exposed to PFOA , the body weight of the mice in RD exposure groups were also significantly decreased , the immune organs showed a serious atrophy , and the number of lymphocytes in the blood had a significant reduction .

实验结果表明：1.注射APH后，随着脾小体缩小和淋巴细胞的减少，脾脏白髓和红髓的琥珀酸脱氢酶、谷氨酸脱氢酶活性逐渐降低，第9天最低，第13天有所恢复。

The data indicate that : 1 . After the injection , the intensity of histochemical reactions for succinic dehydrogenase and glutamate dehydrogenase in the spleen decreased gradually and reached the minimum on the 9 th day .

结果表明：脾脏淋巴细胞数量减少，核内假包涵体形成；

Result shows that lymphocytes reduce and intranuclear inclusions appear in spleen and lymphadens ;

组织学观察，胸腺、腔上囊和脾脏淋巴细胞数量减少、变性、坏死。

Histopathologically , Lymphocytes of thymus , bursa and spleen were reduced , degenerated and necrotic .

淋巴结、脾脏结构破坏，淋巴滤泡消失，脾小体萎缩，淋巴细胞明显减少，组织细胞增生；

The structures of lymph nodes and spleen were damaged with lymph follicles depletion and splenic nodules atrophy .

脾淋巴细胞显著减少，异嗜性粒细胞增多，有多量肿瘤细胞浸润；

The lymphocyte of spleen had decreased , and the heterophilic granulocyte had increased , there was more tumour cell infiltrating .