肝气

目的利用正电子发射成像（PET）脑功能成像技术探讨肝气郁结证在特定脑区功能的改变。

Objective To explore the characteristics of patients with stagnation of liver-qi syndrome using brain functional imaging techniques .

结论：束缚盒慢性应激法可造成小鼠肝气郁结证ED，加强因素可增强ED的程度。

Conclusion : The stressing box can induce and intensify ED associated with liver-qi stasis .

经前期综合征肝气郁证模型大鼠中枢不同脑区ERα和ERβmRNA表达

The Expression of Estrogen Receptor α and β mRNA in Different Brain Regions of Pre-Menstrual Syndrome Model Rats with Liver-qi Depression

经前期综合征（PMS）肝气逆证代谢组学研究

Metabonomics Study on Premenstrual Syndrome with Liver-qi Invasion

利用MMPI临床子量表对20例肝气郁结证患者测试结果分析

Analysis Clinical Sub - scale of MMPI Results for 20 Liver-qi Stagnation Syndrome Persons

偏头痛肝气郁结证、肝火上炎证与健康人MMPI的对照研究

A Control MMPI Study of Migraine On the Liver-Qi , the Liver-Fire and the Liver-Wind

肝气郁结证指甲炭化灰无机元素特征谱只有一个Ca呈正态分布趋势的高峰。

There is only one peak of normal distribution tendency of calcium ( Ca ) in the inorganic elemental characteristic spectrum in charring ash of the fingernails of the patients with liver-qi depression .

经前舒颗粒对PMS肝气郁证模型大鼠不同脑区雌激素受体表达的影响

Experimental Study on Estrogen Receptor Expression Levels in Different Brain Regions of Model Rats with Premenstrual Syndrome Liver-qi Depression

结果：治疗前PMS肝气逆证患者CA总量明显增加，Ad降低，NA含量显著升高，治疗后CA、Ad、NA均得到改善，接近正常水平。

Results : The gross CA increased significantly , Ad decreased , increased greatly in the patients before therapy , CA , Ad , NA were improved or approached natural level .

结论肝气郁证与下丘脑中E、DA、5-HT关系密切，可以部分解释肝气郁证形成原因。

Conclusions depression of liver-qi is in close relation to the increase of some substance such as E , DA and 5-HT , which can partly explain some symptom of liver-qi depression .

目的：探索经前期综合征（PMS）肝气郁证猕猴模型评价指标。

Objective : To probe into indexes of evaluating rhesus monkey model of stagnation of liver-Qi of premenstrual syndrome ( PMS ) .

PMS肝气逆证大鼠含药血清对体外原代培养大鼠大脑皮层神经元活力及5-HT1A受体影响

Effects of PMS Liver-qi Invasion Rat Serum Contained Drugs on Primary Cultured Nerve Energy and Its Serotonin 1A Receptor of Rat Pallium

肝气郁结证、肝火上炎证患者情绪测量及与5-HTT，TPH，ACE基因多态性相关研究

Association Study for Serotonin Transporter and Tryptophan Hydroxylase Gene Polymorphisms and Hepatic Depression Syndrome and Hyperpyrexia of Liver Syndrome Disorder

结果表明，造模后猕猴表情行为变化基本符合临床PMS肝气逆证病证表现；

The result showed that after made model the macaques ' expression and behavior changes generally conform to clinic manifestation of liver-qi invasion of PMS ;

结论：E2、P卵泡期分泌高峰的低平与黄体期分泌峰的阙如是PMS肝气逆证微观机理之一。

Conclusion : Low E_2 and P secretive peak at the follicular phase and lack of secretive peak at the luteal phase is one of the micro-mechanisms of PMS with invasion of the hyperactive liver-qi .

结果发现：肝血虚证上述Hb、血浆NE、E含量及红细胞膜ATP酶活性4项指标均显著低于健康人组及肝气虚证、肝阴虚证组；

The results showed that Hb , NE , E and erythrocyte membrance ATP enzyme activity were obviously lower than those of syndrome of the liver-qi deficiency , syndrone of the liver-yin deficiency and normal persons ;

目的：建立肝气郁结证小鼠勃起功能障碍（ED）模型，检测小鼠性器官的变化，揭示ED发生的可能机制。

Objective : To establish a mouse model of erectile dysfunction ( ED ) induced by liver-qi stasis for observing the changes in the mouse 's sex organs and investigating the possible mechanism of ED.

结果脾虚组患者胃粘膜SOD活性为2.7±1.1U/mg湿重，明显低于肝气犯胃组的4.2±1.7U/mg湿重（P<0.01）；

RESULTS The mucosal SOD activity was 2.7 ± 1.1 U / mg wet weight in SD group , significantly lower than that in LQAS group ( 4.2 ± 1.7 U / mg wet weight , P < 0.01 ) .

基于DRSP的经前期综合征肝气逆证疗效评价参考标准的建立

Establishment of Curative Effect Evaluation Criterion of PMS Liver-Qi Invasion Based on DRSP

在实验研究中，根据导师提出的假说，采用非人灵长类动物猕猴，运用情志刺激，采用择时挤压造模的方法，对经前期综合征（PMS）肝气逆证进行了造模研究。

During the experimental study , according to the hypothesis suggested by tutor , adopt the method of selecting time to make PMS model by emotion stimulus with macaque .

目的：通过对脑卒中后抑郁（PSD）中西医文献的系统性分析，本课题从临床角度观察加味逍遥散对脑卒中后抑郁（肝气郁结型）患者的治疗作用。

Objective : On post-stroke depression ( PSD ) in the systematic analysis of Western literature , the subject of observation from a clinical point of view Xiaoyao post-stroke depression ( qi stagnation ) the treatment of patients .

方法：采用束缚法、居住-入侵法制备PMS肝气郁证大鼠模型，以调肝方药经前舒颗粒进行药物干预。

Methods : Model rats with PMS liver-qi depression were introduced by bondaging the limbs and using the method of resident-intruder respectively , and some of them were treated with Jingqianshu granule .

方法：PMS肝气逆症大鼠模型分别给予不同药物，连续4个月经周期，免疫组化法检测海马5-HT1A受体、5-HT2受体阳性细胞。

Methods : give PMS model rats with liver-qi invasion different medicine for four menstrual periods , and check the positive cell of 5-HT_ ( 1A ) and 5-HT_2 receptor in the rat hippocampi by immunohistochemistry method .

结论：WPD胶囊能通过增强大鼠大脑皮层神经元活力及5-HT1A受体表达以纠正PMS肝气逆证大鼠5-HT1A受体降低趋势，可能是该药治疗PMS肝气逆证的中枢作用机制之一。

Conclusion : WPD capsule can rectify the decrease trend of PMS liver-qi invasion rat nerve serotonin 1A receptor level . Maybe it is just the central mechanism of the new drug curing this syndrome .

目的：探讨肝气郁结证、肝火上炎证与五羟色胺转运体（5HTT）、色氨酸羟化酶（TPH）基因三种多态性的相关性。

Objective : To explore the relationship between the hepatic depression syndrome and hyperpyrexia of liver syndrome disorder and polymorphisms in the serotonin transporter ( 5 HTT ) and tryptophan hydroxylase ( TPH ) .

PSD的发生同时受到中西医易患因素的影响，阴虚证、痰证、瘀证、肝气郁结证、NIHSS积分是主要的中西医易患因素组合。

The occurrence of PSD was influenced by both TCM and Western medicine risk factors . Yin deficiency , phlegm , stasis , liver Qi stagnation and NIHSS points were the main risk factors in the combination with TCM and Western medicine .

结论：从微观角度证实猕猴月经周期与人类的相似性，进一步表明雌性猕猴为经前期综合征（PMS）肝气逆证动物模型的极佳造模对象。

Conclusion : From the microcosmic angle confirming the nature resembling between the macaque menstrual cycle and human being 's , indicating even more that the female macaque is the extremely good object of the animal model of premenstrual syndrome ( PMS ) .

发现肝血瘀阻是肝硬化不同发展阶段的共同病理基础，在肝硬化代偿期，Pugh分级平均3.3分，以肝气郁结为主，以脾虚为辅；

The results showed that Liver - Blood - Stasis was a common pathological basis for cirrhosis in any developing stage ; during compensated stage of cirrhosis , average Pugh Grading was 3.3 , depression of Liver - energy was dominant and Spleen - insufficiency was inferior in this stage ;

推拿治疗肝气郁结型乳腺增生病30例

30 cases with hyperplasia of mammary glands patients treated by Tuina therapy

从临床流行病学调查探讨肝气郁结病机特点

Study of Pathogenic Characteristics of Hepatic Depression Syndrome through Clinical Epidemiologic Survey