美沙芬

目的：验证复方右美沙芬颗粒剂镇咳、祛痰及改善鼻塞的疗效。

AIM : To testify the clinical effect of compound dextromethorphan granule ( CoDMG ) on cough , sputum and nasal obstruction .

右美沙芬对甲基汞致大鼠神经损伤作用的影响液相色谱-串联质谱联用测定人血浆中伪麻黄碱、O-去甲基右美沙芬和苯海拉明的浓度

Effect of dextromethorphan on the neurotoxicity of methyl mercury in rats Simultaneous Determination of Pseudoephedrine , Dextrorphan and Diphenhydramine in Human Plasma by LC-MS / MS

血浆中去甲右美沙芬和愈创木酚甘油醚的HPLC测定

Simultaneous determination of dextrorphan and guaifenesin in human plasma by HPLC

右美沙芬对局灶脑缺血所致的c－fos蛋白表达的抑制作用

Inhibitory effects of dextromethorphan on c fos protein

柱切换HPLC法测定血浆中氢溴酸右美沙芬的代谢物去甲右美沙芬

Column switching HPLC method for determination of dextrorphan , an active metabolite of dextromethorphan , in plasma

乳酸菌奶片加工工艺HPLC法测定氢溴酸右美沙芬口嚼片的含量

Research on Production of the Milk Slice ' of Lactic Acid Bacteria Determination of Dextromethorphan Hydrobromide by HPLC

右美沙芬对大鼠局灶性脑缺血再灌注后神经元损伤及Bcl-2表达的影响

Effects of Dextromethorphan on Neuronal Injury and Expression of Bcl-2 Induced by Focal Ischemia-Reperfusion in Rats

报道了反相高效液相色谱法测定血浆中氢溴酸右美沙芬（DM）方法。

The HPLC method for the determination of dextromethorphan hydrobromide in plasma has been reported .

右美沙芬对培养海马神经元缺氧损伤的保护作用及对Bcl-2表达的研究

The protective action of dextromethorphan against anoxic damage of cultured hippocampal neurons and study on the changes of Bcl-2 expression

右美沙芬对家兔急性脑外伤后脑组织c-fos蛋白和神经元的影响

Changes of C-fos expression and neurocyte necrosis after dextromethorphan therapy for rabbits with acute brain injury

槲皮素竞争性抑制CYP3A2右美沙芬N脱甲基反应，非竞争性抑制CYP2E1氯唑沙宗6羟化反应。

QU exhibited competitive inhibition of CYP3A2 dextromethorphan N-demethylation reaction and expressed noncompetitive inhibition of CYP2E1 chlorzoxazone-6-hydroxylation reaction .

实际上，按照发表在十二月份《儿科学》（Pediatrics）杂志上的另一篇研究，蜂蜜都比右美沙芬（咳嗽糖浆的一种成分）有效。

Indeed , honey is more effective than dextromethorphan , a cough syrup ingredient , according to another study published in the December issue of Pediatrics .

结果右美沙芬组VAS评分在术后8、12、24、48点显著低于对照组（P<0·01），曲马多组在12、24、48h亦显著低于对照组（P<0·05）。

Results After operation , VAS score in group of dextromethorphan was lower than that in control group significantly ( P < 0.01 ) in 8,12,24,48 hours . VAS score in group of tramadol was also lower than that in control group ( P < 0.05 ) .

结果①大鼠给予奥扎格雷钠（37mg·kg-1），其尿样中右美沙芬的代谢率明显高于对照组（P<0·01）；

Results ① In vivo , the DM metabolic rate of treated group ( sodium ozagrel , 37 mg · kg ~ - 1 ) in rat urine was obviously higher than that of control ( P < 0.01 ) .

正交设计法优化复方氢溴酸右美沙芬糖浆的处方工艺

Studies on the Preparation of Compound Dextromethorphan Syrup by Orthogonal Design

右美沙芬代谢多态性分型中的混杂样本剖析法

Dissection of mixed sample for phenotyping of dextromethorphan metabolic polymorphism

氢溴酸右美沙芬片含量分析方法研究

Study on Content analysis method of Dextromethorphan Hydrobromide tablets

人血浆中右美沙芬及去甲右美沙芬的HPLC-荧光法测定

Determination of Dextromethorphan and Dextrorphan in Human Plasma by HPLC with Fluorescence Detection

氢溴酸右美沙芬片人体药代动力学及生物等效性研究

Study on the pharmacokinetics and bioequivalence of dextromethorphan tablet in Chinese healthy volunteers

右美沙芬对兔急性脑外伤后脑血流速度的影响

Effects of dextromethorphan on brain flow velocity in rabbits with acute traumatic brain injury

二溴荧光素-N-氯代丁二酰亚胺化学发光体系测定片剂及人血浆中的氢溴酸右美沙芬

Determination of Dextromethorphan Hydrobromide in Pharmaceutical Preparations and Human Plasma with Dibromofluorescein-NCS Chemiluminescence System

紫外分光光度法测定氢溴酸右美沙芬缓释胶囊的含量及溶出度

Determining the Content and Release Rate of Dextromethorphan Hydrobromide from Sustained Capsule with UV

液相色谱-串联质谱联用测定人血浆中伪麻黄碱、O-去甲基右美沙芬和苯海拉明的浓度

Simultaneous Determination of Pseudoephedrine , Dextrorphan and Diphenhydramine in Human Plasma by LC-MS / MS

右美沙芬对视网膜缺血保护作用的实验研究

Protection of Dextromethorphan in Retinal Ischemia

复方甲氧那明联合右美沙芬治疗上呼吸道感染后咳嗽的疗效观察

The view of effects of compound methoxyphenamine and dextromethorphan for cough Following acute upper respiratory tract infection

目的：建立氢溴酸右美沙芬愈创甘油醚干混悬剂的含量测定方法。

Objective : To establish a method for assay determination of Dextromethorphan Hydrobromide and Guaifenesin for Suspension .

年幼儿童服用右美沙芬存在的潜在副作用包括异常反应、不随意肌严重收缩和痉挛。

Potentially dangerous effects of DM in young children include dystonic reactions , severe involuntary muscle contractions and spasms .

第二晚，孩子们在睡前一小时分别接受了蜂蜜，人工蜂蜜味的右美沙芬，还有一部分则未接受治疗。家长在第二天早上回答了同样的五个问题。

Parents of children who received honey or artificial honey-flavored DM in a measured syringe were blinded to their treatment group .

建立了灵敏度高、选择性好、可同时测定人血浆中右美沙芬活性代谢物去甲右美沙芬及愈创木酚甘油醚的HPLC-荧光检测法。

A new HPLC method with fluorescence detector was developed and validated for the simultaneous determination of dextrorphan and guaifenesin in human plasma .

对双酚伪麻干混悬剂中氢溴酸右美沙芬、盐酸伪麻黄碱测定回收率分别为1000%～1018%和957%～98.7%。

The recoveries of pseudoephedrine hydrochloride and dextromethorphan hydrobromide were ( 95.7 % - 98.7 % ) and 100.0 % - 101.8 % , respectively .