线粒体基因

用MATLAB生物信息学工具箱分析人类线粒体基因序列

Gene sequence analysis of homo mitochondrion using MATLAB bioinformatics toolbox

东方巴贝斯虫EST序列分析及其线粒体基因的测定

Analysis of Babesia Orientalis EST and Sequencing of the Mitochondria DNA

原虫中可能包含核基因、线粒体基因、质粒基因、RNA基因等。

Protozoa may contain nuclear genes , mitochondrial genes , plasmid genes , RNA genes and so on .

太平洋牡蛎核糖体DNA转录间隔子和线粒体基因片段序列测定（英文）马立克氏病毒DNA转录区和非转录区甲基化及脱甲基化的探讨

Sequencing of ribosomal internal transcribed spacer regions and mitochondrial gene fragments in Crassostrea gigas The Study of DNA Methylation and Demethylation on Marek ′ s Disease Virus Genome

该技术体系的建立不仅有助于促进对玉米线粒体基因的研究，而且对其它植物材料的线粒体基因文库的构建也有较大的参考价值，因为其它植物分离大量线粒体和线粒体DNA更不容易。

It is also helpful to those who try to clone mitochondrial genes from other plants because it is more different to isolate mitochondria and mtDNA than from maize .

改良PCR-RFLP法测定异质性线粒体基因的相对含量

Modified PCR-RFLP determination of relative content of heterogenous mitochondrial gene

为了水稻线粒体基因文库的构建和细胞质雄性不育分子机制的研究，用简化的方法提纯了水稻线粒体DNA，限制性内切酶酶切图谱显示了清晰的带型。

In order to construct rice mitochondrial genome library and to study the molecular mechanism of Cytoplasmic Male Sterility , we isolated and purified rice mitochondrial DNA with a simplified method .

提取肿瘤组织总DNA，利用聚合酶链反应（POLYMERASECHAINREACTION，PCR）对线粒体基因4977bp缺失进行检测。PCR产物直接测序。

The total DNA was amplified to identify the 4977 bp deletion of mitochondrial DNA by polymerase chain reaction ( PCR ), and PCR products were verified by direct sequencing .

线粒体基因D-Loop区单核苷酸变异与多囊卵巢综合征的相关性研究

Relationship between single nucleotide variation in mitochondrial DNA D-Loop region and PCOS

苎麻线粒体基因CoxⅡ和atpA与细胞质雄性不育相关性分析

Relationship of Mitochondrial Genes Cox ⅱ and atpA with Cytoplasmic Male Sterility in Ramie

应用LCR技术检测氨基糖甙类抗生素致聋家系线粒体基因的突变

Detection of Mitochondrial Gene Mutation in an Aminoglycoside Antibiotic ? Induced Deafness Family by Ligase Chain Reaction

目的了解优降糖继发失效的2型糖尿病患者对不同胰岛素刺激物的反应，探讨线粒体基因第3243位点A→G突变在优降糖继发失效病因学的作用。

Objective To evaluate the mechanism of secondary failure to glibenclamide in type 2 diabetic patients and the role of mitochondrial gene position 3243 point mutation ( A → G ) in the etiology of secondary failure .

这些微观的能量组拥有不同于细胞核中主基因组的自身的DNA，线粒体基因缺陷可能导致从肌肉无力、心衰竭到脑部疾病等多种疾病。

These microscopic power packs have their own DNA , separate from the main genome in the cellular nucleus , and genetic defects can cause a wide range of medical problems from muscle weakness to heart failure and brain disease .

线粒体基因13513G>A突变导致呼吸链酶复合物I缺陷Leigh综合征

A case of Leigh syndrome associated with respiratory chain complex I deficiency due to mitochondrial gene 13513G > A mutation

五子衍宗汤对Leber遗传性视神经病变患者线粒体基因突变比率的影响

Effect of Wuzi Yanzong Decoction of mitochondrial DNA mutation ratios in patients with Leber hereditary optic neuropathy

结论：增加PCR产物比例，扩大酶切体系，可提高线粒体基因异质性突变的检出率，尽量减少假阴性结果，可应用于临床检测。

Conclusion : The increase of the proportion of PCR products and enlargement of the enzymatic system can improve the detection rate of mtDNA heteroplasmy mutation , decrease false negative results , and can be used in clinic .

结论：本实验直接用PCR扩增乳腺癌血浆核酸中线粒体基因，并用DHPLC初步筛选突变并测序证实。

CONCLUSION : We first amplified mtDNA in circulating plasma from breast cancer patients by direct PCR , checked mutation by DHPLC and confirmed results by sequencing .

用10个线粒体基因为探针，对NCa不育系、保持系和可育F1的苗期叶片、幼蕾及未成熟种子的线粒体RNA进行了Northern分析。

Northern blot analysis was conducted with mitochondrial RNA from seedling leaves , floral buds , and developing seeds of NCa CMS , maintainer line and fertile F1 using ten mitochondrial genes as probes .

在花药败育高峰期（花粉母细胞减数分裂期），与CMS相关的线粒体基因在不育系花药中的表达量要显著低于保持系。

At the peak of anther abortion ( Pollen mother cell meiosis stage ), the expression level of CMS-associated mitochondrial gene in sterile anther was significantly lower than that in maintainer anther . 3 .

目的探讨一个5代遗传的具有独特表型的Leber遗传性视神经病（LHON）家系的线粒体基因突变。

Objective To preliminarily analyze mitochondrial gene mutations of a five generation LHON ( Leber hereditary optic neuropathy ) pedigree with peculiar expression .

结果表明：50个EST可以在Genbank中找到同源序列，其中12个为线粒体基因，12个为功能未知EST，21个为新EST。

The results suggested that 50 EST including 12 mitochondrial genes showed homology with previously identified genes in GenBank DNA database . 12 have uncharacteristic homology in EST database and 21 have no matching sequences .

目的通过了解耐/非耐苯妥英钠（PHT）癫痫鼠与人类同源线粒体基因的差异表达来探索难治性癫痫的分子病理机制。

Objective To explore the molecular mechanism of intractable epilepsy through the differential expression of mitochondrial genes in brains between the phenytoin resistant and non resistant epileptic rats .

目的：探讨1例MELAS患者的临床表现和线粒体基因突变的关系。

OBJECTIVE : To investigate the relationship between the clinical manifestations of a patient with MELAS and a novel mitochondrial DNA mutation .

利用RT-PCR和荧光定量RT-PCR方法研究上述与CMS相关的线粒体基因的表达时，发现在整个花药发育过程中，与CMS相关的线粒体基因在不育系中的表达量总体上要低于保持系。

Analyzing the CMS-associated gene expression with the method of RT-PCR and fluorescent quantitative RT-PCR , the CMS-associated gene expression level in cotton CMS line was lower than that in maintainer line as a whole during the anther developmental stages .

Prev-DAF试剂盒分析线粒体基因1555A-G突变

Mitochondrial DNA 1555A-G mutation analyzed by Prev-DAF testing kit

中国40岁以下发病的糖尿病患者线粒体基因tRNA~（Leu（UUR））A3243G突变的研究

Study on mitochondrial DNA gene tRNA ~ ( Leu ( UUR )) A3243G mutation in patients with below-40-year-old-onset diabetes mellitus in China

故推测小麦D2型光敏性细胞质雄性不育，在长光照条件下，雄蕊雌化与不育表型的表达可能与核基因、线粒体基因和叶绿体基因的表达阻遏调控有关。

So it can be infered from the facts above that on the long-day condition pistillody of stamens in D 2 PCMS line is probably relation to repression of genes expression in nuclei 、 chloroplast and mitochondria .

Leber遗传性视神经病是由于线粒体基因突变导致的母系遗传性常见致盲眼疾。

Leber 's hereditary optic neuropathy ( LHON ) , a common blinding disease , is a maternally inherited degeneration of the optic nerve caused by point mutations of mitochondrial DNA .

目前关于高血压病遗传基因的研究着重于核基因组中可疑致病基因及遗传标志的评估，线粒体基因（mtDNA）突变在高血压发病中的作用仍是一个新的研究领域。

Studies to identify " hypertension " genes have focused on the assessment of markers and candidate genes in the nuclear genome . What role that mitochondrial DNA ( mtDNA ) variations play in the pathogenesis of hypertension is still needed to search for .

目的评价时相温度梯度凝胶电泳技术（TTGE）在肿瘤患者线粒体基因同质性和异质性突变检测中的应用。

Objective To evaluate the potential utility of temporal temperature gradient gel electrophoresis ( TTGE ) in detecting homoplasmic and heteroplasmic mtDNA mutations in patients with cancers .