紧密连接

LN有利于细胞之间形成紧密连接，使胶原纤维集结成束，从而产生致密结缔组织促进肌腱再生。

LN is propitious to formation of intercellular tight junction , bundle the collagen fibrils to come into being tendon .

博莱霉素对大鼠肺微血管内皮细胞紧密连接改变及Cx43表达变化的影响

Changes of tight junction and Cx43 expression in microvessel endothelial cells of mouse lung induced by bleomycin

从本质上说，它们可以相互公开它们的Web服务而不必把每个服务紧密连接到某个类型。

Essentially , they would like to expose their web services to each other without tightly coupling each service to a particular type .

Web服务是以Internet为载体，通过将紧密连接的高效的n层计算技术与面向消息、松散连接的Web概念相结合来实现的。

Web Service is based on Internet and realizes itself by combining efficient n-tiers computation technology and the notions of Web that is message-oriented and LC .

通过免疫荧光和荧光染色观察铜对紧密连接蛋白ZO1和F微丝的影响；

Distribution of tight junctional protein ZO 1 was measured by immunofluorescent staining ; F actin was measured by fluorescence staining ;

该系统与供电企业内的MIS系统紧密连接，实现信息资源共享。

This system and MIS system in the power supply enterprise are close-connected , has realized information sharing .

柯萨奇B3病毒对血管内皮细胞骨架、紧密连接和通透性的影响及p38MAPK的调控作用

P38 MAPK Regulates Vascular Endothelial Actin Cytoskeleton and Associated Tight Junction as Well as Permeability in Response to Coxsackievirus B_3

SOA构建于开放计算之上，它允许系统由与所支持的商业过程紧密连接的一组松散耦合的服务动态组成。

SOA builds on open computing , which allows systems to be dynamically composed by a set of loosely coupled services closely linked to the business processes they are supporting .

电镜下观察见到高切变应力作用48h后，在A和B区紧密连接构造明显增多。

Electron microscopic studies revealed that frequency of tight junctions between endothelial cells in areas A and B was increased by exposure to high shear stress for over than 48 hrs .

有学者通过透射电镜观察发现PR真皮浅层毛细血管的内皮细胞连接处间隙扩大，紧密连接消失或破坏。

By transmission electron microscope , the scholar discovers the junction in endothelial cell of superficial lamella in dermis in PR expands ; tight junction disappears and is ruined .

我们其它的客户经常使用的GDD解决方案包括模块化团队开发以及紧密连接的联合开发。

Other GDD approaches that our customers frequently employ include componentized team development and tightly coupled co-development .

并就细胞分化程度与膜内微粒（IMP）密度的关系以及上皮细胞间紧密连接（TJ）的发育变化两方面进行分析。

The relationship between the density of intramembranous particals ( IMP ) and the developing degree of membrane was analysised .

通过影响actin和ZO-1的细胞膜分布的作用机制打开细胞紧密连接。

The mechanism of opening of tight junctions by SMES might be the change of distribution of ZO-1 and actin .

氧糖剥夺预处理可使脑微血管内皮细胞紧密连接相关蛋白ZO-1和细胞骨架蛋白F-actin的位置改变减轻。

OGD preconditioning could lighten the changes of tight junction proteins ZO-1 and F-actin location . 3 .

血脑屏障的基本结构包括：脑毛细血管内皮细胞及其间紧密连接（TJ），内皮基膜及星形胶质细胞终足。

The blood-brain barrier is composed of a microvascular endothelium and intercellular tight junction , astrocytes , basement membrane .

采用伊文思兰（EvansBlue，EB）和透射电镜技术，检测应用缓激肽前后荷瘤鼠血脑屏障渗透性及紧密连接改变。

Detection of blood-brain barrier permeability as well as the changes of tight junction , using evans blue and electron microscope on tumor-bearing rat before and after bradykinin treatment . 3 .

肝细胞间隙和毛细胆管紧密连接区可见TPPase反应物。

TPPase reaction product in some bile canaliculi decreased .

实验并未发现PAF引起明显的细胞凋亡增加，但透射电镜下出现了紧密连接的断裂和细胞超微结构的破坏。

There was no positive result of apoptosis even given high dose of PAF , but tight junction fracture and cell ultra structure damage appeared under transmission electron microscopy .

结果（1）硝酸镧示踪电镜结果：再灌注0.5h和2h，镧颗粒出现在紧密连接处；

Results ( 1 ) The lanthanum nitrate tracing electron microscope showed that the lanthanum granule ap-peared at the place of close joint at 0.5 h and 2h ;

与细胞增殖相关的分子通路主要包括局部粘附、缝隙连接、紧密连接、细胞骨架调节、p53信号通路、细胞周期、细胞因子与受体相互作用、细胞粘附分子、MAPK信号途径等。

Cell proliferation related pathways including focal adhesion , tight junction , gap junction , regulation of actin cytoskeleton , p53 signaling pathway , cell cycle , MAPK signaling pathway et al were activated in the phase of mesangial proliferation .

ZO-1是组织紧密连接的重要组成成分，其表达上调可调节组织的通透性。

ZO-1 is the important organizational component of tight junctions , and its expression increases the permeability of the organization can be adjusted .

大豆寡糖对免疫功能与肠道紧密连接的影响：测定血浆中免疫球蛋白和细胞因子的浓度；采集脾脏、回肠和结肠组织，分析免疫相关基因和肠道紧密连接基因的mRNA表达。

Effects of SBOS on the immune function and intestinal barrier : the spleen , ileum and colon were collected to determine the expression levels in mRNA of cytokines and tight junctions-associated proteins , as well as the concentrations of immune globulin and cytokines in the plasma .

目的研究缓激肽（BK）对脑胶质瘤大鼠血肿瘤屏障紧密连接的影响。

Objective To investigate the effect of bradykinin ( BK ) on tight junction ( TJ ) of the blood-tumor barrier ( BTB ) and interendothelial TJ of capillaries in brain glioma rats .

结论伤后24h内血脑屏障通透性增高以内皮细胞吞饮活跃为主，伤后24h后以紧密连接开放为主；

Conclusions Within 24h after trauma active pinocytosis of endotheliocyte takes more important role in inducing high permeability of BBB . Then , its chief station is replaced gradually by opening of tight junction of endotheliocyte after 24h after trauma .

采用免疫荧光法评价两种自微乳化系统不同稀释倍数对细胞紧密连接蛋白ZO-1和细胞骨架肌动蛋白（actin）的影响。

Changes in subcellular localization of the tight junction protein zona occludens 1 ( ZO-1 ) and cytoskeleton protein actin by immunofluorescence were also assessed after treatment of two SMESs in different dilutions .

背景和目的：肠粘膜屏障主要由机械屏障、免疫屏障和生物屏障屏障构成，其中以机械屏障最为重要，它包括肠上皮细胞和细胞间的紧密连接（tightjunction，TJ）。

Objective : The intestinal mucosal barrier ( IMB ) is primarily composed of mechanical , biological and immunologic barriers , and the mechanical barrier is the most important component , which including the intestinal epithelial cells and the intercellular tight junction .

细胞接种后4～5d即长成单层，紧密连接，细胞形态多为多边形，部分细胞显示类啤酒杯外观。

The cells grew in single layer after incubation for 4 ~ 5 days , linked closely . Most cells were polymorphic and a part of them were similar in shape to beer glass .

采用Millipore-ERS系统检测内皮细胞紧密连接的功能状态；

The function of tight junctions of in vitro BBB was studied by Millipore-ERS system ;

目的：探讨侧脑室微血管基膜和紧密连接的发育与早产儿脑室内出血的相关性。方法：20例早产儿分为死于脑室内出血（IVH）组和死于非脑室内出血组；

To study correlation between the development of the microvessel basement membrane and tight junction in lateral ventricles and intraventricular hemorrhage ( IVH ) in preterm neonates .

诱导后6d，细胞间出现紧密连接和中间连接，细胞质增多，部分细胞表面出现突起，突起内可见微丝。

On day 6 , plasma and organelle in cells increased , tight junction and intermediate junction were found and there was ( apophysis ) in cell surface and microfilament in apophysis .