神经酰胺酶

果蝇碱性神经酰胺酶（DaCER）特征化及其在发育、存活和繁殖中的作用

Characterization of the Drosophila Alkaline Ceramidase ( DaCER ) and Its Role in the Fly Development , Survival and Reproduction

醛糖还原酶相似蛋白与肝癌发生相关性的初步研究2.高尔基碱性神经酰胺酶调控细胞增殖与存活的研究

The Study in the Relationship between Aldose Reductase-Like Protein and Hepatocarcinogenesis 2 . The Study of Golgi Alkaline Ceramidase Regulating Cell Proliferation and Survival

线粒体神经酰胺酶转染K562细胞，通过其下游代谢产物1-磷酸鞘氨醇，上调抗凋亡蛋白Bcl-2表达水平

Mitochondrial Ceramidase Overexpression Up-regulates Bcl-2 Protein Level in K562 Cells , Probably Through Its Metabolic Product Sphingosine-1-phosphate

方法：1、MTT法检测三种葡萄糖苷神经酰胺合酶抑制剂对人神经胶质瘤细胞增殖的影响。

Method : 1 、 The effect of three different inhibitors of glycosphingolipid biosynthesis on SHG cells growth was measured by MTT assay .

本研究旨在观察葡萄糖神经酰胺合酶（glucosylceramidesynthase，GCS）基因及其蛋白在人白血病细胞的表达及其与肿瘤多药耐药的关系。

This study was purposed to explore the expression of glucosylceramide synthase ( GCS ) in human leukemia cells and its relationship with multidrug resistance .

葡萄糖神经酰胺合酶基因在多药耐药肿瘤细胞株KBV（200）的表达及其与肿瘤多药耐药性的关系

Expression of glucosylceramide synthase mRNA in vincristine-resistant KBV_ ( 200 ) cell line in association with multidrug resistance

目的：1、以人神经胶质瘤SHG细胞为研究对象，观察三种不同的葡萄糖苷神经酰胺合酶抑制剂D-PDMP、NB-DNJ、D-PPMP对SHG细胞增殖的影响。

Objective : 1 , To study the effect of three different inhibitors of glycosphingolipid biosynthesis D-PDMP , D-PPMP and NB-DNJ on SHG cells growth .

糖尿病大鼠神经功能、形态和半乳糖神经酰胺转移酶的变化

Function , Morphology and the Expression of UDP-Galactose : Ceramide Galactosyltransferase in the Diabetic Neuropathy Rats

神经酰胺通过神经酰胺酶水解生成脂肪酸和长链基团，它是以神经酰胺为中心的鞘脂代谢途径的重要组成部分。

Ceramidase hydrolyze ceramide into fatty acid and chain base , which is an important part in metabolic pathway of sphingolipids .

神经酰胺的代谢受多种酶的调控，一些与神经酰胺相关的酶已经报道。

Ceramide metabolism in intracellular was regulated many kinds of enzymes , and has reported several enzymes correlate with ceramide .