磷酸二酯酶

GM1激活环核苷酸磷酸二酯酶的作用

Effect of GM_1 on Cyclic Nucleotide Phosphodiesterase

日本血吸虫cAMP磷酸二酯酶的研究

Studies on cAMP Phosphodiesterase in Schistosoma Japonicum

猪嗜中性粒细胞cAMP磷酸二酯酶的提取与活性检测

Extraction and Activity Detection of cAMP-Phosphodiesterase from Porcine Neutrophils

黄酮类化合物对cAMP磷酸二酯酶抑制的动力学研究

The Inhibition Kinetic Study of Flavonoids on cAMP-PDE

胎儿、孕妇及乙型肝炎患者血清中5′&核苷酸磷酸二酯酶同工酶V的研究

A Research 5 ' - Nucleotide Phosphodiesterase-V in The Sera of Fetuses , Pregnant Women and Patients with Type B Hepatitis

磷酸二酯酶V抑制剂对肺循环血流增多大鼠模型离体肺动脉环的舒张作用

Effects of phosphodiesterase 5 inhibitor on the impaired relaxation of ex vivo pulmonic ring of rats with increased pulmonary blood flow

目的建立大鼠脑组织磷酸二酯酶（PDE）活性测定的HPLC法。

AIM To establish a HPLC method for determining phosphodiesterase activity in rats ' brain .

小鼠U（14）肿瘤组织环&磷酸腺苷磷酸二酯酶活力的初步研究

A Preliminary Study on Cyclic AMP Phosphodiesterase ( PDE ) Activity of Murine U_ ( 14 ) Tumor Tissue

promoterⅡ和promoterⅠ.磷酸二酯酶4D基因与缺血性卒中

Phosphodiesterase 4 D Gene and Ischemic Stroke

牛蒡子与牛蒡子苷对小鼠骨骼肌cAMP及其磷酸二酯酶活性和生长性能的影响

Effects of Fructus Arctii and Arctiin on cAMP and cAMP Phosphodiesterase Activity in Mouse Skeletal Muscle and on Growth Performance

API（0134）对钙调素及其依赖性环核苷酸磷酸二酯酶的作用

The effects of API_ ( 0134 ) extracted from andrographis paniculata on the activities of calmodulin / calmodulin dependent cyclic nucleotide phosphodiesterase

RP-HPLC测定苦木生物碱体外对磷酸二酯酶4的抑制活性

RP-HPLC Method to Assess the Inhibition of Alkaloids in Picrasma quassioides on Phosphodiesterase 4 in Vitro

巴基斯坦人群中磷酸二酯酶4D基因与缺血性卒中的关系

Association of phosphodiesterase 4D gene with ischemic stroke in a Pakistani population

观察到猪苓提取物对于腹水瘤细胞的增殖以及3′，5′cAMP磷酸二酯酶的活性具有平行的抑制效果。

Secondary , parallel inhibitory effects of the activity of 3 ′, 5 ′ cAMP-PDE and proliferation of ascites tumor cells were observed .

磷酸二酯酶（PDE）调节环核苷酸水平，继而影响到Ca2+。

Phosphodiesterase ( PDE ) regulates the levels of cylic nucleotides and then Ca2 + .

癌变过程中酪氨酸转氨酶（TAT）和5′-核苷磷酸二酯酶（5′-NPDase）的变化

Changes of tyrosine transaminase activity and nucleotide 5 ' - phosphodiesterase activity during carcinogenesis

人磷酸二酯酶同工酶3A在昆虫杆状病毒系统中的表达

Expression of human phosphodiesterase 3A gene using baculovirus expression system in insect cell

吗啡依赖小鼠脑组织cGMP水平、鸟苷酸环化酶及磷酸二酯酶活性的调节

Modulation of cGMP levels , soluble guanylate cyclase and phosphodiesterase activities in brain of morphine dependent mice

目的：用阴离子交换HPLC分析环核苷酸磷酸二酯酶反应体系。

Objective : Ion-exchange high-performance liquid chromatography ( HPLC ) was investigated for the analysis of cAMP hydrolysis catalyzed by rabbit liver cyclic nucleotide phosphodiesterase ( PDE ) .

本文报道腺苷酸环化酶（AC）和环腺苷酸磷酸二酯酶（PDE）比活力的放射性同位素测定法。

A method was developed for determination of adenylate cyclase ( AC ) and cAMP phosphodiesterase ( PDE ) specific activities by radioisotopic assay .

伐地那非是一种高选择性的新型磷酸二酯酶5抑制剂，是广泛ED人群的一线治疗药物。

Vardenafil , a novel and highly selective phosphodiesterase 5 inhibitor , is the first line therapy for the broad ED population .

磷酸二酯酶4D基因与缺血性卒中浅谈四冲程摩托车发动机排烟的原因及对策

Phosphodiesterase 4 D Gene and Ischemic Stroke Smoking of 4 - stroke Motorcycle and hs Countermeasures

传统的正性肌力药物&儿茶酚胺类、磷酸二酯酶抑制剂、洋地黄制剂均通过增加细胞内cAMP和Ca2+浓度来提高心肌收缩力。

Common positive inotropic drugs & catecholamines , phosphodiesterase - ⅲ inhibitors and digoxin increased intracellular cAMP of Ca 2 + to enhance the contractility of myocardium .

磷酸二酯酶抑制剂Rolipram对NOD小鼠免疫应答的影响

The role of Rolipram in immune response in NOD mice

咯利普兰对大鼠哮喘模型肺组织磷酸二酯酶及IL-4的影响

The effects of rolipram on PDE activity and IL-4 level in the lung tissue of ovalbumin sensitized and repeatedly challenged rats

浙江产蝮蛇（Agkistrodonhalyspallas）蛇毒的柱层析分离及磷酸二酯酶的大规模纯化

Chromatography fractionation of the venom of Agkistrodon halys Pallas and the purification of the phosphodiesterase

目前认为茶碱类药物毒副作用的产生与其非特异性地抑制磷酸二酯酶（PDE）同工酶有关。

It has been suggested that most of theophylline 's adverse effects are due to the drug 's nonselective PDE-inhibitory actions .

在研究中心进行的、固定剂量的伐地那非研究不能完全代表磷酸二酯酶（PDE）5抑制剂在临床实践中的应用情况。

Since fixed-dose vardenafil clinical trails don 't fully represent utilization of phosphodiesterase-5 ( PDE5 ) inhibitor in general clinical practice .

磷酸二酯酶（PDEs）催化cAMP和cGMP水解开环分别生成AMP和GMP，这是细胞内降解cAMP和cGMP的唯一途径。

Cyclic nucleotide phosphodiesterases ( PDEs ) provide the only route for catalyzing the hydrolysis of cAMP and cGMP into AMP and GMP .

环腺苷酸（cAMP）-特异性磷酸二酯酶4（PDE4）是目前最热门的药物靶点之一。

Type 4 cAMP-specific phosphodiesterase ( PDE4 ) is one of the most popular drug targets .