硬癌

Wnt信号传导通路在胃硬癌形成中的作用

The Role of Wnt Signaling Pathway in Pathogenesy of Scirrhous Gastric Carcinoma

单纯癌大、小细胞型之间、浸润性小叶癌与硬癌之间的Ag&NOR均数有显著性差异（P0.05）；

There was significant difference ( P0.05 ) between large cell type and small cell type of carcinoma simplex or invasive lobular carcinoma and scirrhous carcinoma ;

结果表明：单纯癌、浸润性导管癌、硬癌等癌组织中，CEA阳性率及平均CEA强度均明显高于乳头状癌、髓样癌、髓样癌伴大量淋巴细胞浸润。

The positive rate and density of CEA in carcinomas of simplex , invasive ductal , and scirrhus types were significantly higher than those in papillary , medullary and medullary with abundant lymphoid infiltration carcinomas .

方法：对140例女性原发乳腺硬癌进行回顾性研究。

Methods : One hundred and forty cases of scirrhous carcinoma of breast were discussed in this study .

硬癌X线检出率为71.9%，细针吸细胞学检出率为57.1%。

The detectable rate of X-ray examination of this diease was 71.9 % and that of fine-needle biopsy was 57.1 % .

目的探讨硬癌、不典型髓样癌和典型髓样癌细胞凋亡非基因调控机制与预后关系。

Objective To study the relationship between mechanism of non-gene regulation apoptosis and prognosis of typical medullary carcinoma , atypical medullary carcinoma and scirrhous carcinoma .

目前胃硬癌的发病机制尚未完全阐明，但是越来越多的研究表明大量的细胞因子参与了胃硬癌的发生、发展过程。

At present , the pathogenesy of scirrhous gastric carcinoma has not been clarified completely , but more and more researches show that a large number of cytokines take part in the pathogenesy of scirrhous gastric carcinoma .

结果病理诊断乳腺良性肿瘤229例，乳腺恶性肿瘤29例，其中浸润性导管癌19例，髓样癌7例，硬癌2例，炎性癌1例。

Results Pathological examination showed that of the 258 cases , there were 229 cases of benign mammary tumor , 29 malignant mammary tumor ( 19 invasive and intraductal carcinoma , 2 scirrhus and one inflammatory carcinoma ) .

该方法所获得的人胃成纤维细胞可在体外稳定培养、传代、冻存，为在细胞水平上研究胃硬癌形成机制提供了充足、可靠的细胞模型。

The primary-cultured human gastric fibroblast can be stably cultured in vitro , stored in liquid nitrogen and has stable passage , which provides sufficient and reliable cell models for the research on the pathogenesy of scirrhous gastric carcinoma .

目的通过研究P-钙粘蛋白在乳腺癌及硬化性腺病中表达的不同、淋巴结转移与P-钙粘蛋白表达的关系，探讨P-钙粘蛋白在硬癌和硬化性腺病鉴别诊断中的意义。

Objective To investigate the possible role of p-cadherin ( p-cd ) in the differential diagnosis between scirrhous carcinoma and sclerosing adenosis of breast by measuring the expression of p-cadherin in different breast lesions , and to explore the relationship between the expression of p-cd and lymph node metastasis .