硫氧还蛋白还原酶

目的：探讨大鼠脊髓损伤模型中硫氧还蛋白还原酶（Thioredoxinreductase，TR）的动态表达及其作用。

Objective To study the expression and role of thioredoxin reductase ( TR ) in spinal cord injury model in rats .

目的：观察运动对大鼠心肌、骨骼肌硫氧还蛋白还原酶（TR）的影响。

Objective The present study aimed at investigating the influences of exercise on thioredoxin reductase ( TR ) of myocardium and skeletal muscle in rats .

其它含硒蛋白（如硒蛋白P和硫氧还蛋白还原酶）也具有抗氧化特性。

Moreover , other selenoproteins ( e.g. selenoprotein P and thioredoxin reductase ) also have been shown to possess antioxidant properties .

人硫氧还蛋白还原酶cDNA的克隆及在大肠杆菌中的表达

Cloning of Human Thioredoxin Reductase cDNA and Its Expression in E. coli

灯盏花素对UL补硒大鼠谷胱甘肽过氧化物酶和硫氧还蛋白还原酶基因表达和活性的影响

Effects of Scutellarin on glutathione peroxidase and thioredoxin reductase gene expression and activities in rats supplemented with upper limit Selenium

人脑硫氧还蛋白还原酶的光谱学研究目的：克隆人硫氧还蛋白还原酶（TR）基因并构建原核表达载体，获得TR蛋白。

Spectroscopy Study on Thioredoxin Reductase From Human Brain Objective : To clone thioredoxin reductase ( TR ) gene and express in E. coli .

硫氧还蛋白还原酶是一种NADPH依赖的包含FAD结构域的二聚体硒酶，属于吡啶核苷酸-二硫化物氧化还原酶家族成员。它和硫氧还蛋白、NADPH共同构成了硫氧还蛋白系统。

The mammalian thioredoxin reductases are a family of selenium containing pyridine nucleotide-disulphide oxido - reductases which catalyze the NADPH-dependent reduction of the redox protein thioredoxin .

吉西他滨诱导胰腺癌细胞株SW1990的耐药作用与硫氧还蛋白还原酶活性改变的观察

Induced Drug Resistance and Explored the Changes of the Activity of Thioredoxin Reductase in Pancreatic Cancer Cell Line

目的探讨低硒状态下大鼠心肌线粒体型硫氧还蛋白还原酶（TR2）的活性和表达变化，分析体内硒水平改变对TR2活性的影响及其可能的机制。

Objective To study the changes of activity and expression of mitochondrial thioredoxin reductase ( TR2 ) in activity and possible mechanism .

目的建立对吉西他宾耐药的胰腺癌细胞株，探讨硫氧还蛋白还原酶（TrxR）在耐药过程中的作用。

Objective To establish gemcitabine-resistant pancreatic cancer cell strain and study the role of thioredoxin reductase ( TrxR ) in drug-resistant process .

猪脑硫氧还蛋白还原酶基因片断的序列分析

Thioredoxin reductase gene fragments in porcine brain : sequence study

低硒心肌损伤与硫氧还蛋白还原酶的关系研究

Study of relationship between cardiomyocytes injury induced by selenium-deficiency and thioredoxin reductase

大鼠脊髓损伤模型中硫氧还蛋白还原酶的表达及其作用

Expression and role of thioredoxin reductase in spinal cord injury model in rats

硫氧还蛋白还原酶在大鼠阿尔茨海默病模型海马结构中的表达

Expression of thioredoxin reductase in hippocampus of Alzheimer ′ s disease model in rats

人脑硫氧还蛋白还原酶基因的克隆及测序

Cloning and sequencing of human brain thioredoxin reductase

低硒大鼠心肌线粒体型硫氧还蛋白还原酶的活性和表达

Effect of selenium deficiency on activity and expression of mitochondrial thioredoxin reductase of rat myocardium

硫氧还蛋白还原酶缺陷的大肠杆菌宿主促进含半胱氨酸残基的重组蛋白可溶性表达

The Thioredoxin Reductase-deficient E.coli Mutant Enhances Expression into Solution of Recombinant Proteins Containing Cys Residues

硫氧还蛋白还原酶表达上调治疗非酒精性脂肪性肝病的实验研究

The Experimental Study of the Treatment of Non-alcoholic Fatty Liver Disease Through Thioredoxin Reductase Up-regulated

目的：从人脑组织中克隆硫氧还蛋白还原酶基因。

Objective : To clone the thioredoxin reductase ( TR ) gene from human fatal brain .

结论线粒体型硫氧还蛋白还原酶基因和蛋白表达的增加有利于大鼠心肌抗氧化损伤。

Conclusions The increased expression of mitochondria thioredoxin reductase may protect the heart against oxidative stress injury .

耐力训练和一次性力竭运动对大鼠心肌和骨骼肌硫氧还蛋白还原酶的影响

The Influences of Endurance Training and Single Bout of Exhaustive Exercise on Thioredoxin Reductase of Myocardium and Skeletal Muscle in Rats

目的：探讨补充大剂量硒对谷胱甘肽过氧化物酶和硫氧还蛋白还原酶基因表达和酶活性的影响、以及对大鼠肝组织的作用。

Objective : To study the effects of sodium selenite at large doses on selenoenzyme gene expression and activity in rat livers .

结果应激组大鼠心肌中线粒体型硫氧还蛋白还原酶基因和蛋白表达均高于非应激组。

Results The expressions of the protein and gene of mitochondrial thioredoxin reductase in stress group were higher than those of control group .

本研究进一步比较了纳米硒与硒蛋氨酸的生物利用。研究结果显示，与硒蛋氨酸相比，纳米硒具有相等的效能提高各组织谷胱甘肽过氧化物酶和硫氧还蛋白还原酶的活力。

In this study , the bioavailability of Nano-Se and SeMet was compared , and it was found that , as compared with SeMet , Nano-Se possesses equal efficacy in increasing the activities of glutathione peroxidase and thioredoxin reductase .

硫氧还蛋白、硫氧还蛋白还原酶和NADPH组成硫氧还蛋白系统发挥着抗氧化，抗凋亡及促进细胞增殖等作用。

Thioredoxin system is comprised of thioredoxin , thioredoxin reductase and NADPH , playing multiple biological functions , such as anti-oxidation , anti-apoptosis and promoting cell proliferation .