硫唑嘌呤

贝那普利联合硫唑嘌呤对IgA肾病的疗效观察

The treatment of Benazepril combined with Azathioprine for the IgA nephropathy

硫唑嘌呤及其有效代谢物抑制腺苷激酶（AK），使Ado转变AMP减少，从而增加Ado浓度。

Azathioprine and its potential metabolite inhibits adenosine kinase , diminish AMP formation by adenosine .

C组为CsA、硫唑嘌呤（Aza）和Pred；

Group C receiving CsA , Aza and Pred ;

对不同地区灵芝特性的激光拉曼光谱表征硫唑嘌呤在银电极表面吸附的SERS光谱表征

Raman Spectra and PL Spectra of Ganoderma lucidum SERS for Adsorption Behaviors of Azathioprine Molecules at Silver Surface

经过统计学分析，发现使用普乐可复（FK506）的受者，急性排斥反应的发生率较使用环孢素A和硫唑嘌呤组为低。

The incidence of rejection in the group of patients who received FK506 treatment was lower than that in cyclosporine A and azathioprine-treated group .

肾移植术后均接受环孢素（CsA）、硫唑嘌呤（Aza）和泼尼松三联免疫抑制治疗方案。分别于肾移植后35、34、43个月妊娠。

They all received triple immunosuppressive therapy ( CSA + AZA + prednisone ) for the prevention of acute rejection after renal transplantation .

目的客观评价肾移植术后骁悉（mycohpenolatemofetil，MMF）与硫唑嘌呤（azathioprine，AZA）抗排斥反应效果的差别。

Objective To evaluate the efficacy of mycophenolate Mofetil ( MMF ) and azathioprine ( AZA ) after renal transplantation .

目前治疗SLE的药物包括：非甾体抗炎药、糖皮质激素、抗疟药、免疫抑制剂（包括环磷酰胺、甲氨蝶呤、霉酚酸酯、来氟米特、硫唑嘌呤等）。

There are nonsteroidal antiinflammatory drugs , glucocorticoids , antimalarial agents , and immunosuppressive drugs , including cyclophosphamide , methotrexate and mycophenolate mofetil , azathioprine , which used to treat SLE .

[目的]探讨硫唑嘌呤（AZA）诱导小鼠制作急性肝组织损伤模型的最佳条件。

OBJECTIVE To investigate the optimal condition to induce acute hepatic injury model in mice by azathioprine ( AZA ) .

方法选择尸肾移植患者112例，随机分成两组：MMF（2.0g/d）组和硫唑嘌呤（AZA）组，两组患者均同时接受相似剂量的环孢霉素A（CsA）和类固醇激素治疗。

[ WT5,5HZ ] Methods 112 cases of renal transplant recipients were random divided into two groups : group MMF ( 2.0 g / d ) and group azathioprine A ( AZA ) .

接受硫唑嘌呤治疗的克罗恩患者的红细胞6-TGN水平和血液学参数

RBC 6-TGN and hematological parameters in patients with Crohn 's disease treated by azathioprine

方法将1196例肾移植患者根据其初始的免疫抑制用药方案分为A、B、C三组。A组：环孢素A（CsA）+硫唑嘌呤（Aza）+泼尼松（Pred）；

Methods 1 196 cases of cadaver renal transplant performed in our center were divided into the following groups in terms of the initial immunosuppressant regimen used : Group A : cyclosporin A ( CsA ), azathioprine ( Aza ) and prednisone ( Pred );

而激素、硫唑嘌呤和甲氨蝶呤等西药疗效不肯定，且有较严重的不良反应，临床上常与UDCA联合使用。

But efficacy of western medicines such as the hormone , azathioprine and methotrexate etc. is not sure , and there are more severe adverse reactions , it often used with UDCA .

目的通过对硫唑嘌呤中间代谢物6-巯基嘌呤（6-mercaptopurine，6-MP）药动学的研究，初步探讨巯嘌呤甲基转移酶（thiopurinemethyltransferase，TPMT）活性对6-MP药动学的影响。

OBJECTIVE To study the influence of thiopurine methyltransferase ( TPMT ) activity on the pharmacokinetics ( PK ) of 6-mercaptopurine , which is the intermediate metabolite of azathioprine .

硫唑嘌呤（AZA）/6-巯嘌呤（6-MP）是治疗炎性肠病（IBD）的重要药物，治疗过程中最严重的不良反应是骨髓抑制。

Azathioprine ( AZA ) and 6-mercaptopurine ( 6-MP ) have a well-established effect as an immunosuppressive agent for inflammatory bowel disease ( IBD ), Myelosuppression is the most serious side effect during treatment .

硫唑嘌呤活性代谢产物在炎症性肠病中的临床意义

Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease

肾移植患者术后应用硫唑嘌呤致单纯红细胞再生障碍性贫血

Pure red cell anemia caused by Azathioprine in renal transplant recipients

硫唑嘌呤致血液系统危象的临床特征与酶学基础

Clinical characteristics and enzymology basis of hematological crisis caused by azathioprine

免疫抑制剂硫唑嘌呤对慢性脑血管痉挛的防治作用

Experimental study of the preventive effect of azathioprine on chronic cerebral vasospasm

硫唑嘌呤对环孢素A家兔药动学的影响

The influence of azathioprine on the pharmacokinetics of cyclosporine A in rabbits

肾移植术后吗替麦考酚酯替换硫唑嘌呤的临床分析

Clinical efficacy of azathioprine replaced with mycophenolate mofetil in renal transplant recipients

肾移植后硫唑嘌呤的毒性反应及其治疗

Toxic reaction and management of azathioprine in kidney transplantation recipients

硫唑嘌呤治疗重症肌无力副作用的研究

Side Effect of Azathioprine on the Treatment of Myasthenia Gravis

目的：研究维拉帕米对硫唑嘌呤代谢物6巯嘌呤药动学的影响。

OBJECTIVE : To study effects of verapamil on 6 mercaptopurine pharmacokinetics .

自身免疫性肝炎患者对硫唑嘌呤的耐受不良与硫代嘌呤甲基转移酶缺乏有关

Thiopurine methyltransferase deficiency and azathioprine intolerance in autoimmune hepatitis

维拉帕米对硫唑嘌呤代谢物6-巯嘌呤药动学的影响

Effect of verapamil on 6 mercaptopurine pharmacokinetics in rabbits

6-疏基嘌呤，硫唑嘌呤，8-氮杂鸟嘌呤的滤纸基质室温燐光法研究

The Paper Substrate Room Temperature Phosphorescence of 6-Mercapto Purine , Azathiopurine , 8-Azaguanine

结果术后常规给予环孢素A、硫唑嘌呤和甲基强的松龙三联免疫抑制剂。

Results Cyclosporine A , azathioprine and methylprednisolone were the baseline immunosuppression management .

雷公藤多甙与硫唑嘌呤的免疫抑制作用强度相似。

T_ ( 11 ) and Aza were similar in suppressing immune respone .

硫唑嘌呤氧化反应的荧光光谱法研究

Study on the Redox Reaction of Azathioprine by Spectrofluorimetry