生物碱

双链DNA与生物碱类化合物非共价作用的电喷雾质谱研究

Study on Non-covalent Complexes between Double-stranded DNA and Alkaloid Compounds by Electrospray Ionization Mass Spectrometry

A、C组无异常。结论：可食用植物生物碱无成瘾性，对动物及人体依赖性的戒断作用有重要参考价值。

Conclusion : Alkaloid has no addition and it has important value for withdrawal effect of dependence of creature .

天然C（19）-二萜生物碱的核磁共振谱（Ⅱ）

The natural c_ ( 19 ) - diterpenoid alkaloids and their NMR (ⅱ)

白毛茛中生物碱的提取和HPLC分析

Extraction and HPLC Analysis of Alkaloids in Goldenseal

结论：III是新生物碱。

CONCLUSION : III is a new alkaloid .

钩藤煎煮过程的HPLC研究仿生合成单萜吲哚生物碱

Studies on the Mechanism of Put in Later of Uncaria Hook by HPLC Biomimetic Synthesis of Monoterpenoid Indole Alkaloids

方法：采用改性PVA作为分离膜分离生物碱。

Method s : Modified PVA was used as separating membrane and separated alkaloids .

水溶性生物碱、苦参碱、N－氧化苦参碱、槐定碱，野靛碱、苦豆碱均对松毛虫有不同程度的抑食作用和毒性。

The water solvable alkaloids , matrine , N-oxymatrine , sophoridine , cytisine , aloperine showed feeding inhibition and toxicity to caterpillars at different levels .

目的建立HPLC法测定口服制川乌提取物后大鼠体内乌头类生物碱的方法。

Aim To develop an HPLC method for the determination of Aconitum alkaloids extracted from Radix aconiti preparata in rats .

黄连总生物碱各剂量组均能显著降低大鼠红细胞中AR活性，提示黄连总生物碱可能通过降低大鼠红细胞中AR活性从而保护肾小球的结构和功能。

All doses of Total Alkaloids of Rhizoma Coptidis can decrease the AR activity in rat red blood cells .

与磷酸缓冲体系相比，这种高浓度低pH值的酒石酸缓冲体系能更有效地分离和检测烟草生物碱。

It was found that the tartaric buffer solution at low pH provided higher separation efficiency and detection sensitivity comparing with those of phosphate buffer solution .

目的：研制一种由苦参生物碱和茶皂苷复配而成的创新ST植物杀虫剂。

Objective : To develop a innovative botanical insecticides of TS , which comprises Theasaponin and alkaloid of Radix sophorae flavescentis .

因此，紫堇总生物碱具有降低血压和抑制NA引起的血管的收缩效应。

Therefore , general alkaloid of Corydalis can cause decrease of blood pressure and cause relaxation of aortic muscle precontracted by NA .

昆明山海棠总生物碱对肺腺癌A549细胞株增殖抑制作用的实验研究

Inhibition on proliferation of human lung adenocarcinoma cell line A549 by alkaloids from tripterygium hypoglaucum hutch

目的研究咔唑生物碱HY1对人慢性骨髓性红白血病K562细胞的增殖抑制和凋亡诱导作用，并探讨其作用机制。

Objective To investigate apoptosis-inducing effect and its mechanisms of HY-1 , a carbazole alkaloid , on human erythroleukemia K562 cells .

烟碱（Nicotine），俗名尼古丁，是一种存在于茄科植物中的生物碱，也是烟草的重要成分。

Nicotine is present in the Solanaceae ( Solanum ) of the alkaloid , is also an important component of tobacco .

方法：以TLC法和HPLC法双重鉴定各药材及未知品中酯型生物碱的存在并测定其含量。

METHOD : The existance and contents of double ester alkaloids in every medicinal materials and unknowing materials were carried out by TLC and HPLC .

CONE电压升高后，3个生物碱均发生主要裂解，其中咖啡因和茶碱较可可碱易发生裂解。

In the high cone voltage analysis , three alkaloids take place main fragmentation . The fragmentation of caffeine and theophylline is easier than that of theobromine .

苦马豆素（Swainsonine，SW）属吲哚里西啶生物碱，是疯草（Locoweed）的主要有毒成分。

The indolizidine alkaloid swainsonine is the main toxic composition of Locoweed .

气相色谱/质谱（GC-MS）联用分析食用仙人掌中生物碱类物质基于同步荧光光谱和GC-MS指纹特征的溢油鉴别方法研究

Analysis of the alkaloids in edible cactus by GC-MS Characterization and Identification of Spilled Oils Using Synchronous Fluorescence Spectroscopy and Gas Chromatography-Mass Spectrometry

与对照组相比，博落回生物碱使胸肌在冷藏后MDA含量极显著降低（P0.01）。

Comparing to control group , malondialdehyde ( MDA ) content during cold storage were decreased ( P0.01 ) in breast muscle from chicks fed macleaya alkaloids .

虽然这两种生物碱都含环外乙烯基，Nb-甲基及可能具环醚结构，但是其脂环部分的构造按推断亦不相同。

Although gelsemine and koumine both contain an exo-vinyl , an Nb-methyl and most likely a cyclic ether linkage , the structures of the alicyclic parts of these two alkaloids appear also different from each other .

结果①P-gp检测显示，54.5%的病例对阿霉素、丝裂霉素、长春新碱等抗生素类和生物碱类抗癌药高耐药。

RESULTS ① P-gp detection shew that 54.5 % cases express a high resistance to doxorubicin , mitomycin , vinblastine .

有报道表明TDC酶是长春花生物碱代谢途径的一个限速酶；

It has been reported that TDC is the key enzyme in biosynthesis of alkaloid from Catharanthus Roseus ;

该部分未完成的工作，加深了我们对Schmidt反应和百部生物碱氮杂并环反应性质的认识。

This unfinished work deepened our understanding of the intramolecular Schmidt reaction and reaction properties of the stemona alkaloids ' skeleton .

小檗胺（Berbamine，BER）是从我国中草药小檗属（Berberis）植物中提取的一种双苄基异喹啉类生物碱。

Berbamine ( BER ) is a kind of bis-benzylisoquinoline alkaloids that was extracted from Chinese herb .

狗舌草总生物碱LD（50）测定通过改良寇氏法、腹腔注射给药测定总生物碱对KM雌性小鼠的LD（50）。

LD50 Determination of Alkaloids from I Kirilowii The LD50 of total alkaloids was determined using female KM mice by intraperitoneal injection according to improved Karber 's method .

高分蘖期前用GA3和6BA进行浸根处理，分析GA3和6BA对金钗石斛生长发育及生物碱含量的影响。

, the roots were soaked in different concentrations of GA_ ( 3 ) and 6-BA before the peak tillering stage .

用不同浓度的乙醇和阳离子交换树脂对苦参（Sophoraflavescens）总生物碱进行提取和纯化，并对不同的苦参生物碱纯化工艺进行比较和研究。

Total alkaloid in Sophora flavescens was extracted by different concentration alcohol and resin cation and the purifying technology was studied .

Mannich反应是一类重要的有机合成反应，在医药和生物碱的合成中有广泛的应用价值。

Mannich reaction is an important organic synthesis reaction . It has an abroad application in the synthesis of medicine and alkaloid .