生物标志

作者解释道，升高的皮肤晚期糖基化终末产物（AGE）是糖尿病的生物标志物。

An elevated level of skin advanced glycation end products ( AGE ) is a biomarker of diabetes , the authors explain .

结论：sRAGE是一种新型生物标志物，也冠状动脉粥样硬化呈负相关。

CONCLUSIONS sRAGE is a novel biomarker that is inversely associated with coronary atherosclerosis .

P物质&甲醛急性刺激效应的分子生物标志物

Substance P & the biomarker of acute irritation by formaldehyde

DNA损伤可作为监测海洋石油污染的生物标志物。

DNA damage can be a biomarker to marine oli pollution .

DNA加合物是最重要的化学暴露生物标志物之一。

DNA adduct is one of the most important biomarkers .

鄂尔多斯盆地奥陶系碳酸盐岩沥青A和沥青C的生物标志物特征

Biomarker characteristics of bitumen A and bitumen C of Ordovician carbonate rocks in Ordos Basin

以DNA加合物为生物标志物研究钱塘江水系致癌物水平

DNA adducts as biomarker of carcinogen exposure in wild crucian from Qiantang Valley

醛类化合物DNA化学损伤机制及生物标志物的研究

A Study on DNA Damage and Biomarkers of Aldehydes

DNA加合物作为氯乙烯接触生物标志物的研究

Study on DNA adduct as the exposure biomarker to vinyl chloride monomer in workers

8-羟基脱氧鸟苷是DNA损伤生物标志物中最有代表性的一种。

8-Hydroxy-2 ' - deoxyguanosine is one of the most representative biomarkers of oxidative DNA damage .

因此P物质可作为评价甲醛急性刺激效应的分子生物标志物。

So we can take the substance P as the molecular biomarker of acute irritation by formaldehyde to investigate the biologic effect of formaldehyde .

心电图ST段时值的延长具有独立地反映老龄者衰老程度的生物标志的价值。

The prolonged ST segment may be a independent biomark indicating advanced step of senescence .

可靠、灵敏、准确的分析检测技术是DNA加合物作为生物标志物得到广泛应用的关键。

The reliable , sensitive and accurate detection and identification of DNA adducts is a key to the wide application of DNA adducts as biomarkers .

雄性鱼类VTGmRNA是一种检测环境雌激素的新兴生物标志物。

VTG mRNA in male fish is a new kind of biomarker .

血清GST有可能作为PAHs暴露评价的生物标志；

Serum GST may be used as a biomarker for assessing the exposure of PAHs .

文章对分子生物标志物一生物大分子加合物（如DNA、RNA、蛋白质加合物等）的形成机理以及在环境风险评价中的应用进行了综述；

The formation mechanism and applications to risk assessment of environment of molecular biomarkers-bio-macromolecule adducts ( e.g. , DNA adduct , RNA adduct and protein adduct etc. )

L-1以下的溴氰菊酯对罗非鱼没有生化毒性影响，罗非鱼组织中的CAT和MAO可作为生物标志物来评价农药对鱼类的生化毒性。

The activities of CAT and MAO in fishes could be used as biomarkers to asses the biochemical toxicity of the pesticide to fishes .

以VTGmRNA为生物标志物的环境雌激素筛选方法主要包括实时定量PCR、Northern杂交、原位杂交等。

Environmental estrogens screening methods , with VTG mRNA as a biomarker , include real-time quantitative PCR , Northern blot , in situ hybridization .

服用维生素D的患者，内皮功能障碍的生物标志物如：血清内皮素1、E-选择和MMP-9，水平也较低。

The biomarkers of endothelial dysfunction , serum endothelin-1 , E-Selectin and MMP-9 , levels were also lower for the patients taking vitamin D.

海洋双壳类金属硫蛋白（MTs）即是重金属毒性监测中常用的一类生物标志物。

Metallothioneins ( MTs ) of marine bivalves are common biomarkers which are used in monitoring heavy metal toxicity .

结论T-2毒素能诱导人体HeLa细胞染色质产生凋亡DNA碎片，其损伤特征的存在可作为生物标志，具有在病因流行病学研究中使用的可能。

Conclusions HeLa cell apoptosis was induced by T 2 toxin , and the damage feature might be used in epidemiology study as a biomarker .

利用飞行质谱技术SELDI-TOF-MS从肝癌患者血清中筛选特异的生物标志物

Discovery of Biomarkers from Serum in Liver Cancer by SELDI-TOF Mass Spectrometry

生物标志物组合与苏北金湖凹陷阜二段（Ef2）沉积环境研究

Biomarker Assemblage and Study on Sedimentary Environments of Member 2 of Funing Formation , Lower Tertiary , Jinhu Sag , Subei Basin

目的探求T-2毒素在体内的毒作用靶器官以及对T-2毒素中毒的敏感监测方法和生物标志。

Objective To explore the sensitive organ of T-2 poisoning in rat , and the effective biomonitoring method .

近年来，SERS技术作为一种灵敏的分析手段被初步用于蛋白质的吸附构型研究和细菌芽孢中生物标志物的检测。

Recently , SERS technique has been used as highly-sensitive technique for the detection of structural conformation adsorbed proteins and biomarkers in bacterial spores .

原油生物标志化合物研究发现，西部原油Pr／Ph比值较低，含丰富的伽玛蜡烷、＞C（30）藿烷和硫芴，反映了它们形成于强还原超咸水&咸水环境；

Biomarkers compounds studies show that there are low Pr / Ph ratios , abundant gammacerane and > C30 hopanes and dibenzothiophenes for the western Qaidam oils , reflecting an anoxic and saline-hypersaline environment for their source-rocks .

扇贝消化盲囊和鳃组织中的SOD和CAT活性对壬基酚的反应变化趋势相似，二者结合，可以作为壬基酚污染的生物标志物。

The SOD and CAT activities in the digestive gland and gills showed a similar correlation to NP concentrations , which indicated that the antioxide enzymes in Chlamys farreri were suitable biomarkers of NP pollution .

鉴定了与AMI密切相关的27个生物标志物，主要涉及氧化损伤、能量代谢异常、氨基酸代谢异常及炎症等四个病理过程。

Twenty seven biomarkers have been identified . These biomarkers mainly involved in oxidative injury , dysfunction of energy metabolism , dysfunction of amino acid metabolism and inflammation induced by AMI .

结论尿NAG活性似可作为铅致肾损害的早期生物标志物。

Conclusion The activity of urinary NAG might be used as an earlier biomarker of renal injury for workers with occupational lead exposure .

虽然血清PSA用于前列腺癌筛检虽然有争议，但是在出现更好的生物标志物前，仍然是前列腺癌早期诊断的最佳指标。

Although serum PSA for prostate cancer screening is controversial , but before a better biomarker appears , it is still the best index for early diagnosis of prostate cancer .