珠蛋白基因

人Aγ-珠蛋白基因-173T→C突变对启动子功能的影响

Functional Analysis of Human A γ globin Gene Promoter with - 173 T → C Mutation

α&珠蛋白基因的PCR检测

Diagnosis of the α - globin gene by PCR technique

北京鸭核DNA中β-珠蛋白基因的初步鉴定

Identification of β - globin Gene in Peking Duck 's Genomic DNA

对α链和β珠蛋白基因进行DNA测序。

DNA sequencing on alpha and beta globin chain gene . 3 .

应用长片段PCR技术检测α珠蛋白基因组织的异常

Identification of α globin gene organization using long PCR

5种鲤形目鱼的β珠蛋白基因cDNA的克隆

Cloning of cDNA of β Globin in five species of Cypriniformes

K562细胞7种珠蛋白基因mRNA水平的研究

Comparative study of the mRNA levels of 7 globins in K562 cells

采用PCR结合反向点杂交法检测β-珠蛋白基因17个位点的18种突变；

The mutations of β - thalassemia were identified by using PCR with reverse dot blot hybridization .

用β-珠蛋白基因监测泌尿生殖道标本PCR检测质量

Amplification of β - globin gene to assess the quality of genitourinary tract samples for PCR detection

应用实时定量RT-PCR技术检测β地中海贫血珠蛋白基因的表达

Quantitative Analysis of Human Globin Gene Expression in β - thalassemia Using Real-Time RT-PCR

黄芪多糖诱导K562细胞γ-珠蛋白基因表达

Astragalus polysaccharides-induced γ - globin mRNA expression in K562 cells

β-地中海贫血基因治疗研究&Ⅰ.以逆转录病毒作载体将人β-珠蛋白基因转移至Friend细胞

A Study of Gene Therapy for β - thalassemia & ⅰ . Retroviral-mediated Transfer of Human β - globin Gene into Friend Cells

结论：长片段PCR技术为α珠蛋白基因组织异常的快速检测提供了一个新的方法。

Conclusion : Long PCR provides a new method for the rapid detection of the abnormalities of α globin gene organization .

方法采用PCR-RFLP技术对35例日本人Aγ-珠蛋白基因领域DNA多态性进行了检测。

Methods The PCR-RFLP was adopted to study 35 Japanese DNA-polymorphism of A γ - globin .

荧光定量RT-PCR技术分析人地中海贫血β~（654）珠蛋白基因转基因小鼠mRNA的表达

Analysis of mRNA Expression in Human β ~ ( 654 ) Globin Gene Transgenic Mice by Fluorescent Quantitive RT-PCR

HMG蛋白质与人ε-珠蛋白基因5′旁侧调控元件DNA相互作用

Interactions Between HMG Proteins and 5 ′ Flanking cis Acting Elements of Human ε Globin Gene

方法应用聚合酶链反应（PCR）、Southern印迹杂交和双链DNA循环测序等技术，对在韩国首次发现的中间型β地中海贫血家系的α和β珠蛋白基因进行分析。

Methods Polymerase chain reaction ( PCR ), Southern blot hybridization and double strand DNA cycle sequencing were used to analyse α、β and γ globin gene organization .

氯化高铁血红素诱导K562细胞中β-珠蛋白基因表达的研究

A Study of Inductive Effect of Hemin on Expression of the β - globin Genes in K562 Cells

BAC介导的含97kb人β类珠蛋白基因簇转基因鼠模型的建立

Establishment of BAC Mediated Transgenic Mice Containing 97 kb β - globin Gene Cluster

插入增强子后人β－珠蛋白基因在MEL细胞中的表达

Retroviral-mediated Transfer of Human β - globin Gene and Its Enhancer into MEL Cells

含人β-珠蛋白基因簇的细菌人工染色体（BAC）介导的转基因鼠研究

Transgenic Mice Research Based on BAC Containing the Entire Human β - Globin Gene Cluster

小片段红系特异增强子对MEL细胞中外源β珠蛋白基因表达调控的作用

Small Erythroid Enhancer Fragment on the Expression of Transferred β - globin Gene in MEL Cells

本文分析了四川省10个p地中海贫血家系中β珠蛋白基因簇的限制性内切酶位点多态性和单体型，发现在20条携带β地中海贫血基因的染色体中存在11种单体型。

The restriction endonuclease site polymorphism and haplotype of the β globin gene cluster in 10 β thalassemia families in Sichuan province were analysed . Eleven haplotypes were revealed in 20 chromosomes carrying the β thalassemia gene .

在8只受试BALB/C裸鼠中，RT-PCR在2只BALB/C裸鼠骨髓中检测到β珠蛋白基因的表达。

In 8 recipient BALB / C nude mice , the β - globin gene expression were detected in the 2 mice marrow by RT-PCR .

中国人群β珠蛋白基因簇RFLP连锁不平衡及其在产前诊断中的意义

Linkage Disequilibrium of RFLP on Beta-Globin Gene Cluster and Its Significance in Prenatal Diagnosis of Beta-Thalassemia

人δ珠蛋白基因启动子区CAAT盒C→T突变对其转录的影响

The Transcriptional Regulation Study on Human δ Globin Gene with CAAT Box C → T Point Mutation in Its Promoter

根据α-珠蛋白基因起始密码子上游及终止密码子下游的保守序列设计引物，以牦牛基因组DNA为模板克隆并测定了α-珠蛋白基因序列。

The α - globin gene of yak was amplified and cloned by using the primers based on the conserved region of the upstream from the initiation codon and the downstream from the termination codon .

经Southernblot和Northern－blot分析证实在小鼠BMMC中具有β－珠蛋白基因的整合与表达。

Southern blot analysis and Northern-blot analysis showed that human β - globin gene was integrated and expressed in BMMC .

IL-3对人红白血病细胞株珠蛋白基因表达的影响

Effect of IL 3 on Globin Gene Expression in a Human Erythroleukemia Cell Line

α-珠蛋白基因簇上游亦存在类似的一系列高敏位点（PositiveControlElement，PCE），参与调控α样珠蛋白基因的表达。

In addition , a series of hypersensitive sites ( Positive Control Element , PCE ) located at the upstream of ζ - globin gene , are somewhat like LCR to regulate the a-like globin gene expression .