活性小肽

含亲水氨基酸Asp生物活性小肽的酶促合成

Enzymatic Synthesis of Containing Hydrophilic Amino Acids ASP of Small Bioactive Peptide

抗菌肽（AntimicrobialPeptides）是生物体内经诱导产生的生物界中广泛存在的一类生物活性小肽，是两性分子，常带正电荷。

Antimicrobial Peptides are a kind of bioactive little peptides which exist in biosphere widely . They are amphoteric molecules , produced by induction in organism always with positive charge .

特异性与KDR结合的活性小肽，有望在临床上作为放化疗药物的导向肽，以提高药物的选择性和降低其毒副作用。

The peptide binding to KDR specifically may be helpful for lead drug to improve selectivity and decrease the side effect of anti cancer drug in clinical treatment .

用噬菌体随机肽库筛选刺激细胞生长的活性小肽

Selection of small active peptides inducing proliferation of NFS-60 cells from phage-dis-played peptide library

结论：为活性小肽的体外表达提供了新的思路和方法。

Conclusion This work provides a method for the expression of active small peptide in vitro .

具有SOD和GPX活性的小肽设计及表达研究

Studies on Design and Expression of Small Peptide with SOD and GPX Activities

近几十年来，相继发现了许多有生理活性的小肽，存在于垂体、下丘脑、消化道、各种腺体甚至神经系统、循环系统中。

For decades , a number of physiological active polypeptides were discovered in pituitary , hypothalamic , enteron , all kinds of glands and neural and circulation system . However , these natural proteins were only present in low quantity in nature .

分子生物工程技术已能合成各种生物活性的小分子肽，在它们的分子结构中可引入螯合基团而又不影响它们与受体结合的特性，因而获得高比活度的产品。

Molecular engineering technique now permits synthesis of a wide range of biologically active peptides that carry chelating groups in their structure without their receptor binding properties , thus permitting a high specific activity product .

研究了由毕赤酵母胞内两步发酵法表达活性小分子阿片肽的条件。

The two-step fermentation conditions of opioid peptide expressed in Pichia pastoris were studied .

目的探讨大鼠三肽基肽酶Ⅰ（TPPⅠ）的生物学活性，特别是对具有生物学活性小肽降解的作用机制。

To investigate the bio-activity of TPP I from rat kidneys , especially the hydrolysis mechanism of small molecular peptides .