氨苄西林

HPLC法测定注射用氟氯西林钠氨苄西林钠的含量及有关物质

Determination of flucloxacillin sodium and ampicillin for injection by HPLC

HPLC法测定氨苄西林钠可溶性粉中氨苄西林的含量

Determination of Ampicillin Content in Ampicillin Sodium Soluble Powder by HPLC Method

注射用氨氯青霉素钠中氨苄西林和氯唑西林含量的HPLC测定

Determination of Ampicillin and Cloxacillin in Ampicloxacillin Sodium for Injection by HPLC

反相HPLC法测定注射用氨苄西林钠的含量

Determination of Content in Ampicillin Sodium Injection by RP-HPLC

氨苄西林丙磺舒胶囊的HPLC测定

Determination of Ampicillin and Probenecid Capsules by HPLC

HPLC法同时测定注射用氨苄西林钠/氯唑西林钠的含量

Simultaneous content determination of ampicillin and cloxacillin in a pharmaceutical formulation for injection by HPLC

本文用HPLC法分离测定注射用舒巴坦钠氨苄西林钠中的降解产物、含量。

A HPLC method is developed for the determination of sterile ampicillin sodium and sulbactam sodium .

建立了HPLC法测定复方氨苄西林-氟氯西林胶囊含量及有关物质。

HPLC method was established for the determination of ampicillin , flucloxacillin and related substances in co-fluampicil capsules .

目的建立注射用氟氯西林钠氨苄西林钠含量的HPLC测定方法。

Objective To establish a method for the determination of flucloxacillin sodium and ampicillin sodium for injection by HPLC .

氨苄西林对羊膜腔白介素-6和前列腺素E2释放的抑制作用

Inhibition of amniotic interleukin-6 and prostaglandin E2 release by ampicillin

对氨苄西林-舒巴坦也有一定的耐药，TEM基因阳性志贺菌、TEM基因阴性志贺菌的耐药率分别为41.2%、20.6%。

About 41.2 % of TEM-gene positive S.flexneri and 20.6 % of TEM-gene negative S.flexneri were resistant to ampicillin-sulbactam .

用阳离子交换柱的HPLC法同时测定注射用氨苄西林钠/氯唑西林钠中氨苄西林和氯唑西林的含量。

A newly proposed HPLC method for simultaneous content determination of ampicillin and cloxacillin in a pharmaceutical formulation for injection was developed .

目的建立HPLC测定舒他西林颗粒剂中氨苄西林血药浓度的方法，并研究其在健康人体内的药物动力学。

OBJECTIVE To establish an HPLC-FLU method to measure the plasma concentration of ampicillin in sultamicillin granules and study the pharmacokinetics in healthy volunteers .

用梯度平皿法测定诺氟沙星、四环素、氯霉素和氨苄西林的MIC；

Gradient plates method was used to determine the MIC of norfloxacin , tetracycline , chloramphenicol and ampicillin .

副溶血性弧菌对痢特灵（FR）的耐药率为66.3%，其次是氨苄西林（AMP），为61%。

Drug resistance of V.parahaemolyticus to FR and AMP were 66.3 % , 61 % respectively .

目的评价氨苄西林-舒巴坦组（A组）、头孢哌酮组（B组）、左氧氟沙星组（C组）三种方案对治疗社区获得性肺炎药物经济学成本与效果。

OBJECTIVE To evaluate the cost-effectiveness of three therapeutic schemes , ampicillin-sulbactam injection ( A ), cefoperazone injection ( B ) and levofloxacin injection ( C ) in treatment of the community acquired pneumonia infections .

结果本地区儿童感染Hi对氨苄西林的耐药率为41.77%。β-内酰胺酶阳性率为40.51%。

Results The rate of ampicillin resistance was 41 . 77 % in Hi isolated from children in Nanjing , 40.51 % was found to be bata-lactamase production .

应用国产舒氨西林与氨苄西林随机对照治疗血液病合并感染患者48例，结果舒氨西林临床有效率83.4%，明显优于氨苄西林50.0%（P＜0.05），不良反应轻微。

A randomized comparative study on efficacy of sulbactam / ampicillin in treatment of infections was carried out in 48 patients with blood diseases with a better response rate ( 83.4 % ) in comparison with those obtained by ampicillin alone .

志贺菌对氨苄西林的耐药率高，其中TEM基因阳性志贺菌的耐药率为88.2%、TEM基因阴性志贺菌的耐药率为82.4%；

The S.flexneri isolates were highly resistant to ampicillin . The resistance rate of TEM-gene positive S.flexneri was 88.2 % , and that of TEM-gene negative S.flexneri was 82.4 % .

Hib是儿童呼吸道感染重要血清型，产β内酰胺酶是Hi对氨苄西林耐药的重要机制。

Hib is the important serotype causing respiratory tract infections in children . Beta-lactamase production is the important mechanism of Hi resistant to ampicillin .

结果：青霉素类口服制剂所致过敏性休克20例，其中青霉素V钾片引起8例，阿莫西林引起8例，氨苄西林4例。

Result : 20 cases of anaphylactic shock were attributed to oral penicillins agents , of which , 8 cases were caused by penicillin V potassium tablet , 8 cases by amoxicillin , 4 cases by ampicillin .

方法对鲍曼不动杆菌感染的71例ICU病人进行前瞻性观察，分析泰能和氨苄西林/舒巴坦治疗鲍曼不动杆菌感染病人的临床效果和费用消耗。

Methods A prospective investigation was performed on 71 ICU A. baumannii infection patients treated with imipenem cilastatin and ampicillin sulbactam . The treatment outcomes and antibiotic related costs were also analyzed .

流感嗜血杆菌氨苄西林耐药基因TEM-1、ROB-1的检测

Detection of ampicillin-resistant genes TEM-1 and ROB-1 in Haemophilus influenzae

方法E-test法测定头孢克肟对流感嗜血杆菌（HI）等5种共200株细菌的最低抑菌浓度（MIC），并分别与氨苄西林、头孢克洛、青霉素等作对比研究。

Methods MIC values of Cefixime against 200 strains of five common pathogens were determined with E-test method and compared with those of Ampicillin , Cefaclor and Penicillin respectively .

检测产ESBLs大肠埃希菌时，除氨苄西林双纸片协同法（8/26）检出率低以外，其他4种方法的检出率无明显差异（P>0.05），5种方法有较好的一致性。

Except one kind of double disc synergy test ( 8 / 26 ), other methods showed no difference for the detected ESBLs in E. coli ( P > 0.05 ) .

AuCl4~&鲁米诺体系测定氨苄西林钠

Determination of ampicillin sodium by AuCl_4 ~ & Luminol system

检出株对头孢他啶、氯霉素和阿米卡星等抗生素敏感，对氨苄西林等青霉素耐药性较高，有15.3%（36/236）对弧菌抑制剂O/129纸片（10μg、150μg）有抗性，涉及11个血清型。

Detected strains were sensitive to ceftazidime , chloramphenicol and amikacin , relatively high resistant to ampicillin etc. 15.3 % ( 36 / 236 ) belonged to 11 serotypes and were resistant to the drug O / 129 ( 10 μ g and 150 μ g ) .

金黄色葡萄球菌和大肠埃希菌对萘啶酸和诺氟沙星的耐药升至50%以上，甲型副伤寒沙门菌则高达96%～97%，对氨苄西林、头孢唑林也都有明显升高（P0.01）；

Staphylococcus aureus and Escherichia coli resistant to nalidixic acid and norfloxacin were above 50 % , while Salmonella paratyphi A was 96 97 % , whose drug resistance to ampicillin and cefazolin had an obvious rise also ( P0.01 );

bro1阳性菌株对氨苄西林、头孢克洛的MIC90值与bro2阳性菌株相比，有不同程度的升高。

Compared with bro-2 positive strains , the MIC value of ampicillin and cefaclor for bro-1 positive strains were higher .

ESBLs产生株对氨苄西林、哌拉西林、奥格门丁及三代头孢菌素高度耐药，除头孢他啶以外，耐药率均在80%以上；

ESBLs-producing strains were much higher resistant to ampicillin , piperacillin , the combination of amoxicillin with clavulanic acid and third-generation cephalosporins , except ceftazidime , the resistant rates were more than 80 % ;