氨基甙类抗生素

小诺霉素（MCR）是小儿常用的新型氨基甙类抗生素，其耳毒性迄今了解甚少。

Micronomicin ( MCR ) is a new aminoglycoside antibiotics of usual uses in pediatry , its ototoxicity has been known little up to now .

氨基甙类抗生素（AmAn）是一类有效抗革兰阴性菌抗生素，但由于耳毒性和肾毒性，临床应用受到限制。

Aminoglycoside antibiotics ( AmAn ) are effective drugs in therapy against gram-negative infections , but the ototoxicity and nephrotoxicity limit their use in clinic .

结论AAID属线粒体遗传，对具有AAID家族史的个体（尤其是母系亲属），应当避免使用氨基甙类抗生素。

Conclusion The inheritance mode of AAID is mitochondrial inheritance . Aminoglycoside antibiotic therapy should be avoided in those persons with a family history of AAID , especially their maternal relatives .

氨基甙类抗生素对家兔离体颈动脉窦压力感受器放电的抑制作用

Inhibitory effect of aminoglycoside antibiotics on rabbit carotid baroreceptor activity in vitro

氨基甙类抗生素致聋的遗传流行病学研究

A genetic epidemiological study of aminoglycoside antibiotic induced deafness

40例患儿中，22例有明确的氨基甙类抗生素应用史。

Among the 40 children 's examination , there are 22 children on whom the aminoglycoside antibiotic agent had been applied .

结论：该突变是氨基甙类抗生素耳毒性遗传易感性的分子生物学基础。

The relationship between the audiovestibular changes and genetic susceptibility to aminoglycoside ototoxicity and the pathogenetic mechanism of susceptible deafness are discussed .

氨基甙类及青霉素类抗生素在水牛体内代谢动力学的研究

Pharmacokinetics study of aminoglycosides and penicillins antibiotics in buffaloes