杂环化合物

含氮杂环化合物环境参数及生物活性的QSAR研究

QSAR study on environment properties and biological activities of nitrogen-containing heterocyclic compound

Pd催化的C-C键和C-N键的生成，是合成具有生物活性杂环化合物一种重要手段。

The formation of C-C bond and C-N bond using Pd-catalyzed methods is an important means to synthesize bioactive heterocyclic compound .

某些氚标记杂环化合物的~3HNMR研究

~ 3H NMR Analysis of Some Labeling Heterocyclic Compounds

碘杂环化合物的~1HNMR谱研究一种新型碘杂环化合物（Ⅳ）的合成

Study on ~ ( 1 ) H NMR Spectra of Heterocyclic Compounds Containing Iodine

四氮唑及2（1H）-喹啉酮类含氮稠杂环化合物及其衍生物是重要的医药中间体，其药物广泛应用于心血管类疾病的治疗。

Tetrazole and carbostyril and their derivatives are widely applied as cardiovascular drugs .

含硒杂环化合物的合成和对超氧阴离子作用的ESR研究

Studies on the syntheses of selenium heterocycle compounds and their effect on superoxide radicals by ESR

若干芳香杂环化合物在DMSO溶液中pKa值的密度泛函计算

DFT calculation of pKa for some aromatic heterocyclics in DMSO Solution

而当R为吸电子基团-CHO、-COCH3时，主要发生分子内氮原子上的亲核取代反应，产物为含氮的五员杂环化合物。

In contrast , electro-withdrawing groups CHO and COCH_ 3 on the attacking site will favor the intramolecular nucleophilic substitution of nitrogen and form 5-membered heterocyclic compounds .

此外，它还可以通过杂Diels-Alder反应合成六元杂环化合物。

And it can synthesize six-member heterocyclic compounds by aza-Diels-Alder reaction .

用杂原子DielsAlder反应合成六元含氟杂环化合物。

The hetero Diels Alder reactions to six membered fluorinated heterocycles .

多环吡啶、多环吲哚等天然杂环化合物具有优良的抗菌、抗肿瘤、抗HIV等生物活性。

Natural heterocyclic products such as polycyclic pyridines and polycyclic indoles exhibit a broad range of biological activities , such as antibacterial , antitumor , anti-HIV , and so on .

本文主要研究了通过Pd催化，实现C-H键的活化，生成含氮氧的杂环化合物。

This thesis was concerned with the study on the synthesis of heterocyclic compounds containing nitrogen and oxygen via Pd-catalyzed C-H activation .

抗疟新药的研究&具有对-氨基酚双Mannich碱的杂环化合物的合成

Studies on new antimalarials & synthesis of heterocyclic compounds carrying double Mannich basic chains of p-aminophenol

本论文以荧光和紫外-可见光谱为研究手段，研究了几类含氮杂环化合物与牛血清白蛋白（BSA）的相互作用。

In the thesis , we study the interaction of nitrogenous heterocyclic compounds and bovine serum albumin ( BSA ) by fluorescence and UV-vis spectroscopy .

PEG-400中某些杂环化合物的合成研究

Study on the Synthesis of Some Heterocyclic Compounds in PEG-400

苯并噻唑类及咪唑类杂环化合物具有独特的生物活性，在农药、医药等领域有着广泛的应用，例如用于抗HIV病毒、抗癌、抗菌以及植物病毒等。

Benzothiazoles and imidazoles derivatives have unique physiological and biological activities and have a wide range of applications in medicine , pesticide and other fields , such as anti-HIV-1 , anticancer , antimicrobial and plant virus .

含N-O键的双环杂环化合物和海洋Butenolides的合成

Synthesis of Bicyclic Heterocycles Containing an N-O Bond and Marine Butenolides

应用有机物结构－活性定量关系方法（QSAR）对杂环化合物的好氧生物降解性能与其化学结构间的关系进行定性、定量分析。

The quantitative and qualitative analysis were conducted on relativity between aerobic biodegradability and chemical structure of heterocyclic compounds by applying organics quantitative structure activity relativity ( QSAR ) .

除了脂肪胺外，多种异芳基溴代物甚至氯代物也能很好地与含N-H杂环化合物进行偶联。

Apart from alkyl amines , many aryl bromides , even heterochorides could be efficiently coupled by N-H heterocycles .

表面增强拉曼散射光谱（SERS）分析证实了含氮或含硫的芳杂环化合物化学吸附在银的表面，并形成了平躺取向的自组装膜结构。

The surface-enhanced Raman scattering spectroscopy ( SERS ) analysis verifies that two nitrogen-containing or sulphur-containing aromatic heterocyclic compounds were chemisorbed onto the Ag-plated carbon fibers and formed a lie-down phase .

第二部分：3（2H）-呋喃酮类衍生物是一类重要的杂环化合物，它具有较高的药理活性，是一类在天然产物合成中具有重要作用的合成砌块。

2 ) The 3 ( 2H ) - furanones are an important class of heterocyclic compounds , which are of pharmacological significance and represent useful building blocks for natural products syntheses .

炒籽30min后氮杂环化合物含量随炒籽时间迅速增加，取代非杂环类化合物成为花生油中主要风味物质。

N-heterocyclic comounds increased significantly and replaced non-heterocyclic compounds to be the major flavor components of peanut oil after 30 min-roasting .

Ugi反应作为多组分反应中最重要的反应之一，在合成多肽及其类似化合物和杂环化合物领域中有着广泛的应用。

Multicomponent Ugi reaction is one of the most important reactions in the synthesis of similar compounds and heterocyclic compounds .

发展了一种新的杂环化合物2-巯基苯并咪唑（MBI）修饰金电极用于含有表面活性剂的溶液中铜的直接伏安检测的方法。

A novel method for the direct determination of copper containing surfactant on a heteroaromatic compound MBI modified gold electrode was proposed .

碘杂环化合物IHC-72、利多卡因及维拉帕米抗心律失常作用的比较

Comparison of antiarrhythmic effects of ihc-72 ( an iodonium-72 ), lidocaine and verapamil

第一章综述了PEG在有机合成方法学上的优势及其在有机合成方面的主要成就：包括生物大分子的合成，有机小分子的合成，杂环化合物的合成与PEG支载的催化剂和试剂。

Chapter one The superiority of PEG in organic synthetic methodology and the main achievements in organic synthesis are reviewed , including the synthesis of biological macromolecules , organic small molecules and heterocyclic compounds and the PEG bound catalysts and reagents .

含氮、含硫和含氧杂环化合物会通过抑制细胞色素P450酶的氧化反应而对微生物产生毒性，致使生化法难以处理该类化合物废水。

Heterocyclic compounds containing nitrogen , sulfur , or oxygen atom were highly toxic to microorganism through inhibiting cytochrome P450s mediated oxidation , resulting in that biodegradation is unsatisfactory for effective abatement of these compounds in wastewater .

本文阐述了羰基通过叠氮化物和三价膦形成的亚胺基膦的作用，以氮杂wittig反应的方式，合成含氮杂环化合物的进展。

This Paper focus on recent synthetic development of aza-Wittig reaction in nitrogen heterocyclic and explains some mechanism of the reaction of carbonyl compounds with organic azides and tertiary phosphines .

根据GC-MS分析，亚、超临界醇解产物的组成很复杂，可检测出数十种化合物，主要是糠醛（纤维素和半纤维素的主要醇解产物）、含氧有机物、含苯环化合物和杂环化合物。

Dozens of organic compounds were detected by GC-MS analysis from supercritical alcoholysis products , and most of the species detected are furfural which is the main product of the cellulose and the hemicellulose and oxygen-containing organic chemicals , especially the methoxy compounds .

随着科技的发展，又出现了分子内的Diels-Alder反应以及杂Diels-Alder反应，它们是有机化学中合成六元环状化合物、六元杂环化合物的重要手段。

Alder . Along with the development of the science and technology , Intramolecular Diels-Alder reactions and Hetero-Diels-Alder reactions appear . They are important methods of synthesis of hexatomic ring and hexabasic heterocyclic compound .