最大血药浓度
- 网络CMAX
最大血药浓度-
结果最大血药浓度时两个对映体在人体血浆中的浓度有不同程度的差异。
RESULTS The plasma concentrations of two enantiomer were different .
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利用聚乙二醇作为药物载体，往往会具有溶解性增强、半衰期加长、最大血药浓度降低、酶降解作用变少、免疫原性及抗原性更小等特点，是解决喜树碱临床应用限制最有效的方法之一。
The use of PEG as a drug carrier , often with a solubility enhanced , half-life prolonged , maximum plasma concentration decreased , enzymatic degradation lessen , immunogenicity and antigenicity of decreased , is one of the most effective methods to solve the problems of clinical application of camptothecin .
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产生50%最大药效的血药浓度C（50）亦有变异，个体间差异3.6&5.2倍。
The C_ ( 50 ) plasma concentration producing 50 % of maximal pharmacological effects , is also varied , ranging from 3 . 6-5 . 2 folds .