恶性高热
- 网络malignant hyperthermia;malignant hyperthermia,MH;Malignant Hyperpyrexia
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一例恶性高热病人在ICU急救的护理报告
Nursing report of one malignant hyperthermia patient in ICU emergency
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恶性高热症(MalignantHyperthermia,MH)是一种罕见的常染色体显性疾患,此病的易感个体在接触某些麻醉药物时可发生危及生命的高代谢状态。
Malignant Hyperthermia ( MH ) is a rare autosomal dominant disorder in which susceptible individuals may develop a potentially life threatening hypermetabolism when they were exposed to certain anesthetic agents .
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恶性高热(MH)是一种致命的生理反应,可能是由某种麻醉剂或肌肉松弛剂引起的,免疫力地的病人更加危险,这可以通过使用无刺激性的麻醉剂而避免。
MH is a potentially fatal reaction to certain anesthetic agents and muscle relaxants in susceptible patients that can be avoided by using alternative non-triggering agents .
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结论:恶性高热是一个独立性疾病,麻醉用药是诱因,血清Ca2+、CK显著升高是其重要指标;
Conclusions : MH is a kind of disease that can be brought out by anesthetics . High levels of serum Ca 2 + and creatine kinase are the major marks of MH .
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已发现恶性高热症与ryanodine受体基因(RYR1)缺陷相关。
It was realized that MH is associated with defects of the ryanodine receptor ( RYR1 ) gene .
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目的应用咖啡因-氟烷骨骼肌收缩试验(CHCT)明确恶性高热(MH)的诊断。
Objective To explore the application of caffeine-halothane contracture test ( CHCT ) in the confirmation of malignant hyperthermia ( MH ) .
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结论:发现中国人种恶性高热患者RYR1基因新的突变位点,且均为无义突变,可以引起蛋白质结构和功能的改变,其机制尚需进一步研究。
All of the mutations are nonsense mutation . These can induce the structure of protein change which needs further studies .
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中央轴空病患者畸形矫正术中的恶性高热风险
Morbidity of Malignant Hyperthermia in Central Core Disease Patients Undergoing Orthopedics
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恶性高热的早期诊断及丹曲洛林缺乏条件下的治疗方案
Early diagnosis of malignant hyperthermia and its treatment regimen without dantrolene
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恶性高热症的研究进展
Research Advances in Malignant Hyperthermia
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血清钙及肌酸激酶显著升高是恶性高热的重要指标。
High levels of serum Ca 2 + and creatine kinase were the important signs of MH .
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第一部分恶性高热的临床研究目的:通过对湖南地区临床确诊为恶性高热患者的病例资料进行分析,了解恶性高热病人的诱发因素、临床表现及特点。
Part 1 Analysis of Clinical Features for Malignant HyperthermiaObjective : Through the analysis of clinical data of malignant hyperthermia patients in Hunan , to investigate the precipitating factors 、 clinical manifestations and characteristic .
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方法:总结和归纳4例临床诊断为恶性高热病例的麻醉方式、麻醉药物、临床表现、化验检查、抢救措施及临床转归等临床资料。
The characteristics of the four cases , including drugs and methods of anesthesia , clinical manifestations , and results of lab examination , emergency treatment methods and prognosis were reported . Results : MH is highly occurs in young people , more frequently in males than females .