平衡易位携带者

16例平衡易位携带者的妊娠结局

The gestation results in 16 cases of chromosome balanced translocation carrier

染色体9；13平衡易位携带者引起的习惯性流产一例报告

One Case of Chromosome 9 ; 13 Balanced Translocation Carrier Causing Habitual Abortion

一位46，XY，t（11；18）平衡易位携带者的联会复合体分析

Analysis of Synaptonemal Complex from a Carrier with 46 , XY , t ( 11 ; 18 ) Balanced Translocation

另1例的父亲为平衡易位携带者（14q；21q）。

The father of the other case was a balanced carrier ( 14q ; 21q ) .

对染色体异常检出率、额外小染色体及平衡易位携带者进行了讨论。

Detective rate , small accessory chromosome and balanced translocation are discussed .

胚胎植入前遗传学诊断在平衡易位携带者中的作用

The role for preimplantation genetic diagnosis in balanced translocation carriers

目的研究染色体平衡易位携带者的生育能力及妊娠风险。

Objective To investigate the reproductive ability and pregnancy outcome of balanced translocation carriers .

平衡易位携带者的遗传性分析

A genetic analysis of balanced translocation carrier

平衡易位携带者怀孕时必须做产前诊断。

After becoming pregnant the carriers of balanced translocation must be examined by prenatal diagnosis .

染色体平衡易位携带者生育风险研究

Reproductive risk of balanced translocation carriers

t（14；21）平衡易位携带者体细胞和生殖细胞的细胞遗传学研究（英文）

Somatic Cell and Sperm Cell Cytogenetics in a Patient with t ( 14 ; 21 )

3例平衡易位携带者所致习惯性流产的遗传效应分析

Analysis of the genetic effect of 3 habitual abortion patients that they were carriers of balanced translocation

方法对1例t（11；22）平衡易位携带者的三孕进行分析。

Methods : Analysis three times of pregnancy in a t ( 11 ; 22 ) balance translocation carrier .

130例平衡易位携带者共有473次妊娠，流产占90.1%，死胎、分娩异常后代、分娩正常后代、分娩易位后代分别为4.7%、4.0%、1.1%、0.2%。

There were 473 pregnancies in 130 carriers of balanced translocations ; their spontaneous abortions rate was 90.1 % .

其父为罕见的2对平衡易位携带者，但表型正常。

His father was a carrier of two apparently unrelated balanced reciprocal translocations , but his phenotype was normal .

目的探讨t（11；22）平衡易位携带者对子代的影响。

Objective : To investigate the effect of t ( 11 ; 22 ) balance translocation carrier on filial generation .

通过遗传咨询门诊，对反复性流产患者夫妇双方或一方进行了染色体核型分析，共71例，检出平衡易位携带者3例。

The karyotypes cf71 cases of recurrent abortion , or their couples were examined in genetic definition clinic , 3 cases of anomalous karyotype were observed .

结果检出染色体平衡易位携带者35例：常染色体相互易位25例，罗伯逊易位9例，复杂易位1例。

Results 35 cases of balanced translocation were discovered ( 25 cases of reciprocal autosomal translocation ; 9 cases of robertsonian translocation ; 1 case of complex translocation ) .

染色体平衡易位携带者由于自身染色体是平衡的因此没有异常表型，但将导致不育、流产、死胎、畸胎、胎儿宫内和出生后生长缺陷。

Although the carriers of chromosomal balanced translocation have normal phenotypes they would lead to infertility , abortion of fetus , malformation of fetus and congenital defects after born .

结果871例孕妇中，发现唐氏综合征2例，X-三体综合征1例，平衡易位携带者3例，其它胎儿异常6例。

Results There were 2 cases of Down Syndrome , one case of trisomy X syndrome , 3 cases of balance translocation carrier and 6 cases of other abnormalities among the 871 cases .

6例异常包括：在9例夫妇一方为染色体平衡易位携带者对象中发现2例；结论染色体平衡易位携带者的异常孕产以孕早期自然流产为主要表现。

Abnormal karyotypes were detected in 6 cases ( 2.9 % ) . Conclusion Spontaneous abortion in the first trimester was the main mode of abnormal pregnancy in the carriers of balanced chromosomal translocation .

对13例平衡易位携带者进行产前诊断，正常核型7例，携带者核型5例，染色体异常胎儿1例，表型异常者7例，占12.5%。

Finally , the prenatal diagnosis has been performed in 13 balanced translocation carriers and the results showed that there were 7 fetuses with normal karyotype , 5 with abnormal karyotype and 1 with chromosomal abnormality .

作者在1988年10月至1992年4月间对16例非同源平衡易位携带者包括8例孕前和孕期中药治疗者的妊娠结局进行随访。

The authors reported the gestation results were followed up from Oct.1988 to Apr , 1992 in 16 cases of non-homologous chromosome balanced translocation carrier . The 8 cases of them were given by traditional Chinese medicine before and during gestaton .

平衡易位和倒位携带者对子代的影响

The effect on filial generation of patients balance translocation and inversion

目的研究平衡易位和倒位携带者对下一代的影响。

Objective : To study the effect on filial generation of patients with balance translocation and inversion .