天冬氨酸蛋白酶

华支睾吸虫组织蛋白酶D样天冬氨酸蛋白酶全长基因的生物信息学分析在三羧酸循环中天冬氨酸可以被分解。

Bioinformatics Analysis of the Full-length Cathepsin D-like Aspartic Protease Gene from Clonorchis Sinensis Aspartic acid can be broken down in the KREBS CYCLE .

酸性蛋白酶，又叫天冬氨酸蛋白酶，是一种在酸性环境下可以将蛋白质分解成多肽或氨基酸的酶类。

The acid protease , also known as aspartic protease , is a sort of enzyme which can break down protein into polypeptide or amino acid .

细胞色素c介导的半胱天冬氨酸蛋白酶-3活性改变与人卵巢癌顺铂耐药的关系

Relationship between cytochrome c-mediated caspase-3 activity and chemoresistance in cisplatin-resistant human ovarian cancer cell lines

各组大鼠肠上皮细胞半胱氨酸天冬氨酸蛋白酶-3及Bcl-2基因的表达。

The expression of caspase-3 and Bcl-2 gene in rat intestinal epithelium .

目的研究半胱氨酸天冬氨酸蛋白酶3（caspase-3）表达在老年贲门癌发生发展中的作用。

Objective To study the role of caspase-3 expression in carcinogenesis and progression of cardia cancer .

半胱氨酸-天冬氨酸蛋白酶（Caspase）及其在细胞凋亡中的作用

Caspase and its effects on apoptosis

兔耳慢性缺血性溃疡愈合过程中增殖细胞核抗原、半胱氨酸天冬氨酸蛋白酶3和c-myc的表达

Expression of proliferating cell nuclear antigen , caspase-3 and c-myc in the healing of chronic ischemic ulcer in rabbits ' ears

westernblot及激酶活性测定法检测海马内半胱天冬氨酸蛋白酶-3（Caspase-3）的表达和活性，琼脂糖凝胶电泳观察海马神经元凋亡；

Western blot and kinase activity assays were used to determine the expression and activity of Caspase-3 in the hippocampus . The hippocampal neuronal apoptosis was observed by DNA electrophoresis .

脂蟾毒配基引起细胞线粒体膜电位下降，释放入胞质中的细胞色素C增多，促进半胱氨酸天冬氨酸蛋白酶3蛋白活化，抑制Bcl-2蛋白表达，诱导细胞凋亡。

Resibufogenin could induce the decrease of cell mitochondria membrane potential , increase cytochrome C in kytoplasm , enhance Caspase 3 activation , inhibit the expression of Bcl-2 protein and result in cell apoptosis .

目的探讨细胞凋亡因子Caspases（半胱天冬氨酸蛋白酶）增加是否与妊娠期肝内胆汁淤积症（ICP）的发病具有相关性。

Objective : To explore whether the up-regulation of Caspases is correlated with the mechanism of Intrahepatic Cholestasis of Pregnancy ( ICP ) .

采用免疫组化法测定灯盏花素干预大鼠脑缺血24h后对Bcl-2蛋白、c-Fos蛋白、半胱氨酸天冬氨酸蛋白酶3蛋白表达的变化。

The expressions of Bcl 2 , c Fos and Caspase 3 proteins were detected by using immunohistochemical method 24 hours after the treatment of cerebral ischemia reperfusion injury with breviscapine .

胃蛋白酶（Pepsin）是胃中最重要的消化性蛋白酶，属于天冬氨酸蛋白酶家族，主要负责食物蛋白质的初步水解。

Pepsins , with responsibility for the preliminary digestion of proteins in the stomach , are important gastric digestive proteinases belonging to a family of aspartic proteinases .

目的：探讨灯盏花素干预脑缺血再灌注损伤后对Bcl-2蛋白、c-Fos蛋白、半胱氨酸天冬氨酸蛋白酶3蛋白的表达影响及其对大脑损伤的保护作用。

AIM : To study the effect of breviscapine on the expression of Bcl 2 , c Fos and Caspase 3 proteins in rats with cerebral ischemia reperfusion injury and the protective role in brain .

本文综述了常用的细胞凋亡检测技术与方法的基本原理，如形态学观察、荧光素染色、DNA阶梯、半胱氨酸天冬氨酸蛋白酶活性的检测等，并对各种方法的优点及局限性做一简要比较。

This review focuses on the techniques and methods that are currently used for the detection of apoptosis , such as morphological observation , fluorescence staining , DNA ladder , caspase activity , etc , and on the evaluation of the advantages and limitations of these methods .

结论：肺癌A549细胞对肿瘤坏死因子相关凋亡诱导配体细胞耐受，姜黄素可能通过调整bcl-2/bax的表达，进而激活半胱氨酸天冬氨酸蛋白酶家族，增加肿瘤坏死因子相关凋亡诱导配体的敏感性。

CONCLUSION : Lung adenocarcinoma A549 cells are resistance to TRAIL ; the curcumin can activate the caspase family to improve the sensibility of TRAIL by modulating the expression of bcl-2 / bax .

细胞凋亡（apoptosis）失衡与许多疾病密切相关，而半胱天冬氨酸蛋白酶（caspase）是执行细胞凋亡的蛋白酶家族，在凋亡过程中发挥关键作用，它可通过多种途径发生级联激活。

Apoptosis is involved in a variety of diseases . Cysteine aspartate specific protease ( caspase ), a protease family which executes apoptosis , plays a crucial role in course of apoptosis . It can be activated through various pathways .

目的评估分泌型天冬氨酸蛋白酶（Sap）抑制药胃酶抑素A（PepstatinA）在播散性白念珠菌感染中的治疗作用，并探讨Sap在小鼠播散性白念珠菌感染过程中的作用。

Objective To evaluate the therapeutic effect of the Sap inhibitor pepstatin A and explore the role of secreted aspartyl protainase ( Sap ) in disseminated Candida albicans infection in mice .

目的探讨半胱氨酸天冬氨酸蛋白酶-3（caspase-3）抑制药Ac-DEVD-CHO与钙拮抗药尼莫地平对神经元缺血性损害的协同保护作用。

Objective To test the synergetic protective effects of combined cysteine asparate pro-tease-3 ( caspase-3 ) inhibitor Ac-DEVD-CHO and calcium antagonist nimodipine on ischemic neuronal injury in vitro model .

目的：观察中药蟾酥主要成分之一&脂蟾毒配基对体外培养人胃癌BGC-823细胞系细胞生长的干预及其与细胞色素C和半胱氨酸天冬氨酸蛋白酶3活化的关系。

AIM : To observe the intervention of resibufogenin , one of main components of Chinese herb venenum bufonis , on the growth of human gastric cancer BGC-823 cell line cell cultured in vitro , and the relationship with cytochrome C and Caspase-3 activation .

米黑毛霉（M.miehei）天冬氨酸蛋白酶的研究

Studies on Aspartate Proteinase From M.miehei

TUNEL标记及计数的各组大鼠半胱氨酸天冬氨酸蛋白酶3表达的结果：对照组及4h组仅见偶染细胞，8h后开始出现阳性细胞，主要位于灰质中；

Caspase-3 expression with TUNEL and counting in rats of every group : In the control and 4 hours group , stained cell was seen occasionally and positive cell appeared 8 hours later , mainly localized in gray matter .

用免疫组化染色检测半胱氨酸天冬氨酸蛋白酶3阳性细胞。

The caspase - 3 positive cells were detected with immunohistochemistry .

高糖通过活化半胱氨酸天冬氨酸蛋白酶3途径诱导人腹膜间皮细胞凋亡

High glucose induces apoptosis of human peritoneal mesothelial cells by caspase-3 activation

婴幼儿皮肤血管瘤组织中半胱氨酸天冬氨酸蛋白酶-3和内皮抑素的表达

Association of caspase-3 and endostatin expression in infantile dermal hemangiomas

双后肢腰椎退行性变大鼠椎间盘半胱氨酸天冬氨酸蛋白酶3的表达

Expression of caspase-3 in degenerative lumbar intervertebral disc of bipedal rat models

缺氧缺血性脑损伤鼠半胱氨酸天冬氨酸蛋白酶-1的表达及其意义

Expression of caspase-1 after hypoxic - ischemic brain damage

凋亡相关基因和半胱天冬氨酸蛋白酶-3在卵巢癌顺铂耐药细胞株中的表达

Role of apoptosis-associated genes and caspase-3 in cisplatin-resistant human ovarian cancer cell lines

辛伐他汀对大鼠系膜细胞增殖、凋亡及细胞内半胱氨酸天冬氨酸蛋白酶3表达的影响

Effects of simvastatin on proliferation , apoptosis and caspase-3 expression of rat mesangial cell

高分子聚乙烯和氧化铝陶瓷磨损颗粒诱导细胞凋亡及与半胱氨酸天冬氨酸蛋白酶3信号传导的相关性

Correlation between apoptosis induced by alumina and high-molecular-weight polyethylene particles and the signal conduction of caspase-3

采用流式细胞仪检测骨巨细胞瘤细胞凋亡率，同时检测半胱氨酸天冬氨酸蛋白酶3蛋白活性的表达情况。

The GCT cell apoptosis rate and the activation of caspase-3 were detected with flow cytometer .