地黄饮子

目的：观察地黄饮子对脑血管性痴呆的临床疗效。

OBJECTIVE : To observe the clinical effect of Rehmannia Decoction in treating cerebrovascular dementia .

地黄饮子对海马神经元损伤即早基因c-jun和c-fos表达的影响

Effect of Decoction of Rehmanniae on Immediate Early Gene c-jun and c-fos of Hippocampal Neurons Model injury

地黄饮子可以通过增强痴呆鼠脑CAT抗氧化酶的活性、降低MAO活性以抑制过氧化反应，进而提高对自由基清除能力，减少自由基对海马神经元损伤。

DR pretects hippocampal neurons from the damage of free radicals by improving the activity of antioxidative enzyme CAT and decreasing MAO in rats brain .

与模型组比较，BMSCs组、维甲酸组和地黄饮子组脑组织病理损伤程度减轻。

Compared with the model group , pathological destruction of brain tissue in BMSCs group , ATRA group and Di Huang Yin Zi group are reduced .

地黄饮子能通过改善鼠脑神经元胆碱能损害，来上调海马和皮层神经元SYN蛋白的表达，使突触传递功能恢复。

DR increases the expression of SYN of cortical and hippocampal neurons by improving the injury of cholinergic neuron to recovery the function of synaptic transmission .

目的：探讨古方地黄饮子对β淀粉蛋白（Aβ25～35）所致离体海马神经元损伤时即早基因CJUN和CFos表达的调控作用。

Objective : To investigate repressive effects on the expression of IEG c jun and c fos of Decoction of Rehmanniae on cultured hippocampal neurons injury induced by β amyloid 25 ~ 35 protein ( A β 25 ~ 35 ) .

地黄饮子近20年的研究

Study of Radix Rehmanniae Decoction in the Recent Two Decades

方法：采用地黄饮子加减配合针刺治疗。

Method : Modified Dihuang decoction and acupuncture were used for treatment .

以含2%和4%地黄饮子培养基饲养果蝇观察其对果蝇寿命的影响。

Effect Of Dihuang Yinzi decoction on lifespan of fruit fly were studied .

加减地黄饮子提取工艺的研究

Study on Extraction Process for Decoction of Rehmanniae

地黄饮子对犬心肌缺血模型心血管血液动力学的影响

The Effect of Di Huang Yin Zi on Hemodynamics in the Myocardial Ischemia Dog

地黄饮子对阿尔茨海默病模型鼠脑神经元细胞凋亡及超微结构的影响

Effect of rehmanniae decoction on the neuron apoptosis and ultrastructure in rat models of Alzheimer disease

地黄饮子对Aβ致海马神经元损伤影响的实验研究

Experimental Research of Effect of Decoction of Rehmanniae on the Injury of Hippocampal Neurons Induced by Amyloid β - Protein

结果：地黄饮子能缩短模型大鼠避暗学习、记忆潜伏期，减少错误次数；

Result : To AD model Rats , DYD can contract latency of learning and memorizing and decrease mistakes in step-through methods ;

结果显示：一、地黄饮子能有效改善海马神经元生存状态，提高细胞生存活力。

The results show : 1 , Decotion of Rehamanniae can significantly ameliorate the existent state of hippocampal neurons and increase the activity of neurons .

目的：观察地黄饮子煎剂对改善男性高血压患者性功能障碍的影响。

Objective : To observe the curative effect of Uihuang Yinzi Decoction ( DYD ) for sexual disorder ( SD ) in hypertension of male .

以氯化铝诱导痴呆小鼠模型，观察地黄饮子对小鼠在跳台实验、水迷宫实验中学习记忆能力及脑组织中乙酰胆碱酯酶活性的影响。

METHODS By the way of one trial passive avoidance response ( step down , step through ) and water maze methods to test the ability of learning and memory in mice .