化脓性链球菌

Ahmed青光眼阀门植入术后迟发性化脓性链球菌眼内炎

Delayed-onset Streptococcus pyogenes endophthalmitis following Ahmed glaucoma valve implantation

目的：A族链球菌（GAS，又称为化脓性链球菌）可以引起多种人类疾病，最常见的GAS感染是上呼吸道感染，引发咽炎。

Objective : The bacterial pathogen group A Streptococcus ( GAS ; Streptococcus pyogenes ) causes many distinct human diseases . The most common GAS infections are those of the upper respiratory tract , leading to development of pharyngitis ( strep throat ) .

化脓性链球菌感染患者给予青霉素G480万U，静脉滴注速率33滴/min，给药时间间隔12h。

The patient with infection of S.pyogenes was administered penicillin G in a dose of 480 ten thousand U twice daily by intravenous infusion , transfusion speed was 33 drops / min.

另外，还对江苏省送检的从患儿血培养基培养的细菌毒株进行了鉴定，对其16SRRNA基因进行了基因扩增及序列分析，序列测定和分析提示为A组M3型化脓性链球菌。

In addition , one bacteria strain cultured from the blood of a patient was identified belonging to A group type M3 pyogenic streptococcus using 16S rRNA gene amplification and sequencing analysis .

对点滴型银屑病患者咽部培养获得的化脓性链球菌进行PCR检测，经检测确认含有M6蛋白基因表达的菌株进行分离提纯M6蛋白。

M6 protein expression in the streptococus from pharynges patients with guttate psoriasis was examined by polymerase chain rection ( PCR ) and the protein was then purified from the becteria .

结果5年间共检出乙型溶血性链球菌58株，且以化脓性链球菌为主，其次是无乳链球菌、G群溶血性链球菌，而马链球菌、F群溶血性链球菌较少见；

Results : During five years , there have been 58 strains streptococci , beta-haem to be detected , S. pyogenes was in the majority , then was S. agalactiae and group G streptococci beta-haem , S. equi and group F streptococci beta-haem were scare .

结果：头孢硫脒对肺炎球菌、化脓性链球菌、MSSA、MSSE和卡他布汉氏菌有较强的抗茵活性。

Results : Cefathiamidine had a stronger antibacterial activity to S. pneumoniae , S. pyogenes , MSSA , MSSE and B. catarrhalis .

37%～41%化脓性链球菌耐大环内酯类；

Pyogenes to macrolides was 37 % ~ 41 % .

芯片已经被用来比较表现得到修改体外生长条件征收强调化脓性链球菌在快速增长。

Microarrays have been used to compare the expression profiles obtained by modifying in vitro growth conditions to impose stress on S.pyogenes during exponential growth .

虽然已知化脓性链球菌感染需要许多的致病因子参与其中，但是真正的细菌致病分子机转仍未被了解透彻。

Although there are many virulence factors that have shown to be involved in GAS infection , the actual molecular mechanism of bacterial pathogenesis in GAS is far from clear .

实验研究结果并结合此次疫情的流行病学和患儿的临床表现，证实腺病毒3型是引起此次儿童不明原因轻型呼吸道传染病暴发的病原体，部分病例伴有原发或继发化脓性链球菌感染。

In this paper , by comprehensive analysis of epidemiology , clinical symptoms and laboratory data , it indicated that adenovirus type 3 was the main etiologic agent of this unknown mild respiratory tract infectious disease outbreak , some patients may have original or secondary acquired pyogenic streptococcus infection .