副肿瘤综合征

目的探讨特异性抗神经元抗体对神经系统副肿瘤综合征（paraneoplasticsyndromeofnervoussystem，PNSNS）早期诊断的意义。

Objective To study the significance of anti-neuronal antibodies in the early diagnosis of paraneoplastic syndrome of nervous system ( PNSNS ) .

现已证实，HuD的低表达与视神经发育障碍、先天性巨结肠等疾病相关，其多克隆抗体anti-Hu抗体在副肿瘤综合征、假性肠梗阻等多种疾病的发病机制中扮演一定角色。

It is proved that there is some certain relationship between HuD low expression and Hirschsprung disease . The polyclonal antibody , anti-Hu antibody , plays a role in pathogenesis of paraneoplastic syndrome and pseudo-intestinal obstruction .

目的研究副肿瘤综合征（PNS）自身抗体（抗Hu抗体）对培养神经细胞的直接影响。

Objective To examine the direct effects of the autoantibody ( anti-Hu antibody ) of paraneoplastic neurological syndrome on primary-cultured neurons .

FDG-PET可提高神经系统副肿瘤综合征患者的肿瘤检出率

FDG-PET improves tumour detection in patients with paraneoplastic neurological syndromes

自身抗体对副肿瘤综合征诊断价值的探讨

The Role of the Autoantibodies in Diagnosis of Neurological Paraneoplastic Syndrome

副肿瘤综合征，神经系统；肺肿瘤；诊断。

Paraneoplastic syndrome , nervous system ; Lung neoplasms ; Diagnosis .

抗-Hu抗体相关神经系统副肿瘤综合征的免疫学和电生理学的实验研究

Immunological and Electrophysiological Study of Anti-Hu-Associated Paraneoplastic Syndromes of Nervous System

神经系统副肿瘤综合征的临床表现分析

Analysing the Clinical Characteristics of Paraneoplastic Syndrome of Nervous System

19例副肿瘤综合征患者临床分析

The Clinical Analysis of Paraneoplastic Syndrome : 19 Cases

抗神经元抗体对副肿瘤综合征早期诊断的临床意义

Clinical Significance of Anti-neuronal Antibodies in the Early Diagnosis of Paraneoplastic Neurological Syndromes

转移至肝脏，很少引起副肿瘤综合征。

Metastatic carcinoid to the liver can rarely result in the carcinoid syndrome .

探讨副肿瘤综合征患者的临床特征及诊断方法。

To discuss the clinical characteristics and diagnosis of paraneoplastic syndromes ( PS ) .

目的：了解神经系统副肿瘤综合征患者的临床表现特点。

Objective : To investigate the clinical characteristics of4 cases with paraneoplastic neurological syndromes .

目的探索肺癌所致神经系统副肿瘤综合征的护理特点。

Objective To study the nursing method of paraneoplastic neurological syndromes caused by lung cancer .

特异性神经元抗体对神经系统副肿瘤综合征筛检价值的研究

Study on the value of specific neuronal antibody in screening for paraneoplastic syndromes of nervous system

方法回顾性分析1990～2000年北京协和医院副肿瘤综合征患者的临床资料并加以总结。

Methods The clinical data of patients with paraneoplastic neurological syndromes from 1990 to 2000 were retrospectively analyzed .

目的探讨以运动神经元病为表现的副肿瘤综合征的临床、电生理学、病理学特点。

Objective To investigate the clinic , electrophysiological , pathological characters of paraneoplastic syndrome which manifested with motor neurone disease-like .

结论神经系统副肿瘤综合征的护理在注意原发病护理的同时，更要注意到副肿瘤综合征症状及体征的护理。

Conclusion The nursing of original disease as well as the symptom and sign of paraneoplastic neurological syndromes are both important .

方法18例病人采用了基础护理与心理护理，及针对副肿瘤综合征症状及体征的护理。

Methods Basic nursing , psychological nursing and the nursing aiming at the symptom and sign of paraneoplastic neurological syndromes were taken among18cases .

结论：副肿瘤综合征可出现在实体肿瘤或白血病患者，它的出现几乎均预示着预后不良。

Conclusion : Paraneoplastic neurological syndromes may appear in the patients with tumor or acute granular cell leukemia , and commonly signifies a poor prognosis .

诊断出副肿瘤综合征时，26.9%肿瘤已出现转移。

When the cancer was founded , 26.9 % had already metastasized and the time from onset to tumor diagnosis was about 18 ± 6 months .

结果副肿瘤综合征平均发病年龄48.6±26岁，男性占69.2%，女性占30.8%。

Results The mean onset ages of patients with paraneoplastic neurological syndromes were 48.6 ± 26 years old . 69.2 % of the patients were male , 30.8 % were female .

报告15例神经系统副肿瘤综合征患者血清和脑脊液中存在特异性神经元抗核抗体。

The presence of neuronal antinuclear antibodies ( NAA ) in sera and CSF of 15 patients with paraneoplastic sydromes of the nervous system ( PNSNS ) were identified with immunohistochemistry ( ABC method ) and Western blot analysis .

神经系统副肿瘤综合征和肿瘤浸润、转移或致代谢异常等所致神经系统损害，在临床表现上与其他原发神经系统疾病不易区分，容易误诊，应当提高警惕，注意鉴别。

The nervous system damages caused by the tumor infiltration , metastasis and paraneoplastic neurological syndrome are difficult to distinguish from the other nervous system disease in clinical manifestations and are easily misdiagnosed , the doctor should be vigilant .

神经系统副肿瘤性综合征患者体内特异性神经元抗体的研究

Study on Specific Neuron-antibody in Patients With Paraneoplastic Syndrome of Nervous System

Hu抗体测定在副肿瘤性神经综合征随访中的价值

Value of Hu antibody determinations in the follow-up of paraneoplastic neurologic syndromes

目的探讨肺癌的副肿瘤性神经综合征（PNS）的临床特点以防止肺癌诊断的延误。

Objective To discuss the clinical features of paraneoplastic neurological syndromes ( PNS ) of lung cancer in order to prevent misdiagnosis of lung caner .

一项利妥昔单抗治疗副肿瘤性神经系统综合征相关抗体的非对照试验

An uncontrolled trial of rituximab for antibody associated paraneoplastic neurological syndromes

副肿瘤性神经系统综合征的临床分型、相关肿瘤及免疫学研究

An immunological study of paraneoplastic neurological syndromes associated with malignant tumors and clinical types