前列地尔

为评价经尿道使用前列地尔（PGE1）对ED的治疗作用。

Transurethral delivery system of alprostadil ( PGE 1 ) was used to 40 men with erectile dysfunction .

前列地尔治疗重型病毒性肝炎42例

Alprostadil in the Treatment of 42 Patients with Severe Viral Hepatitis

方法将108例因肾毒性药物所致急性肾损害患者为三组，A组36例，用前列地尔10μg，静脉推注，1次/d；

Methods 108 patients with drug-induced acute renal damage were divided into three groups at random .

治疗后两组血小板聚集率均较治疗前有明显改善（P值均<0.01），且前列地尔组较丹参组下降更为明显（P<0.01）。

Concomitantly , inhibition of platelet aggregation of the alprostadil group also improved more significantly ( P < 0 . 01 ) .

ADR发生频率最高的为前列地尔注射液（凯时），占9.02%；

Alprostadil Injection accounted for 9.02 % of the total , the highest .

目的：观察前列地尔注射液（前列地尔脂微球载体靶向制剂）对脑梗死病人血小板P选择素的影响及临床疗效，探讨其治疗脑梗死的作用机制。

Objective : To observe the effect of Alprostadil on the P-selection of platelet and clinical curative effect of Alprostadil in patients with cerebral infarction . To explore the treatment mechanism of it .

结论：前列地尔对D-氨基半乳糖致急性肝损伤大鼠有肝脏保护作用，其机制可能与降低肝脏IL-18水平有关。

Conclusion : Alprostadil prevented the rats from D-Gal-induced hepatic injury by inhibition of IL-18 levels .

前列地尔对体循环压力和心率影响不明显，而酚妥拉明使体循环压力下降，并明显加快心率（P均<0.01），对患者血流动力学影响较大。

Lipo-PGE1 showed no significant effect on systemic circulation pressure and heart rate . Regitine showed significant effect on hemodynamics which decreased the pressure of systemic circulation and increase heart rate significantly ( P < 0.01 ) .

目的观察前列地尔（prostaglandinE1，PGE1）对大鼠乙酸性结肠炎的影响。

Objective To study the effect of prostaglandin E1 ( PGE1 ) on rats colitis induced by acetic acid .

目的观察前列地尔（注射用前列腺素E1，PGE1）治疗重症心力衰竭的疗效。

Objective To observe the effects of prostaglandin E_1 ( PGE_1 ) on patients with severe heart failure .

目的探讨中药足浴和前列地尔脂微球载体（商品名为凯时）联合治疗糖尿病足（DF）的有效性和安全性。

Objective To explore the efficacy and safety of combination of foot bath of Chinese medicine and Kaishi on diabetic foot ( DF ) .

目的：评价前列地尔在造血干细胞移植中预防肝静脉闭塞病（hepaticveno-occlusivedisease，HVOD）的作用。

Objective : To evaluate the effect of alprostadil for the prevention of hepatic veno occlusive disease ( HVOD ) after hematopoietic stem cell transplantation .

目的探讨前列地尔（凯时）治疗下肢动脉硬化症（LEASD）的疗效观察及相关护理。

Objective To investigate the effect of prostaglandin E and the associated nursing on patients with lower extremity atherosclerosis disease ( LEASD ) .

目的：观察前列地尔对D-氨基半乳糖致急性肝损伤大鼠肝匀浆IL-18水平升高的抑制作用。

Objective : To evaluate if and how alprostadil for injection inhibits IL-18 levels in rats with D-galactosamine ( D-Gal ) - induced acute hepatic injury .

目的：研究前列地尔脂微球载体注射液（Lipo-PGE1）对大鼠小肠淤血性损伤的保护作用。

Objective : To study protective effect of Lipo-PGE_1 for injection on intestinal congestion in rats .

结论：前列地尔降低大鼠血管球囊损伤术后血浆中ET及血清中IL-1β，IL-6，TNF-α水平的作用，是其干预血管再狭窄形成的重要机制。

CONCLUSION : The reduction of the plasma levels of ET and the serum levels of IL-1 β, IL-6 and TNF - α plays an important role in the protective mechanisms against vascular restenosis of alprostadil .

目的观察前列地尔脂微球载体注射液（Lipo-PGE1）对慢性重型肝炎患者血清肿瘤坏死因子-α（TNF-α）、白细胞介素-8（IL-8）水平的影响。

Objective To assess the effects of lipo-PGE_1 injection on the serum levels of INF - α and IL-8 in patients with chronic severe hepatitis .

结论IL-1β、HCY与2型糖尿病周围神经病变的发生、发展有密切关系，而前列地尔能降低DPN患者血浆IL-1β、HCY水平。

Conclusion The serum levels of IL-1 β、 HCY were associated with the development of DPN , PGE1 can reduce serum levels of IL-1 β and HCY of DPN group .

方法对确诊的10例脑出血后PTE的患者，给予前列地尔注射液10μg/d静脉滴注，连续14d为1个疗程。

Methods 10 patients with PTE after cerebral hemorrhage were given Lipo-PGE_1 injection 10 μ g / d by intravenous drip . 14d was one course of treatment .

治疗组在给予治疗冠心病药物的基础上加用前列地尔注射液（凯时）10μg加20mL生理盐水静脉注射，1次/d，2周为一疗程；

The routine treatment was used in both groups , alprostadil injection 10 μ g in normal saline 20 mL was added in the treatment group by intravenous injection once a day for two weeks .

目的比较口服西地那非（SIL）与静脉应用前列地尔（PGE1）治疗先天性心脏病（先心病）术后肺动脉高压（PH）的早期疗效。

Objective To compare the effects of oral Sildenafil ( SIL ) and intravenous prostaglandin E_1 ( Alprostadil , PGE_1 ) in treatment of postoperative pulmonary hypertension ( PH ) associated with congenital heart defects ( CHD ) .

目的观察前列地尔（PGE-1）联合奥扎格雷治疗急性脑梗死的疗效。

Objective To observe the clinical efficacy of PGE-1 combined with Ozagrel in treating acute cerebral infarction .

结果：8例患者中1例发生HVOD且合并肾功能衰竭，经加大前列地尔用量，联合血液透析、丹参等治疗后痊愈。

Results Of eight patients , only one developed HVOD ( 14.3 % ), and HVOD was rapidly cured by hemodialysis one time in combination with double - dose alprostadil .

方法对30例重症急性胰腺炎患者给予前列地尔（lipoPGE1）40μg/d治疗，观察临床症状及体征，肝、肾功能，动脉血气分析及血清TNFα水平的变化。

Methods Lipo PGE1 ( 40 μ g / d ) was given to 30 severe acute pancreatitis patients . The clinical symptoms and signs , hepatic / renal function , arterial blood gas analyses and TNF - α were observed .

前列地尔对肾移植后早期肾功能恢复的影响

Effect of Alprostadil on Recovery of Early Graft Function After Renal Transplantation

前列地尔治疗慢性肾衰竭20例临床观察

Clinical Study of Lipo PGE1 in Treating Chronic Renal Failure

前列地尔联合弥可保治疗糖尿病周围神经病变疗效观察

Clinic Effect of Alprostadil Combined with Methycobal in Treating Diabetic Peripheral Neuropathy

目的探讨前列地尔注射剂对慢性肾功能不全的疗效。

Objective To study efficiency of prostaglandin EI for chronic renal disfunction .

结论：前列地尔是治疗突发性耳聋的有效药物。

CONCLUSION : Alprostadil injection is an effective drug for sudden deafness .

前列地尔联合腺苷钴胺治疗2型糖尿病周围神经病变疗效观察

Treatment effect of alprostadil combined cobamamide on diabetic peripheral neuropathy