冰片

冰片开放血脑屏障及通过P糖蛋白介导的机制研究

Study on the Auxo-action of Borneol Accelerating the Penetration of BBB and P-glycoprotein-mediated Mechanism

采用气相色谱法（GC）测定冰片的含量。

Synthetic Borneol was determined by GC .

GC测定复方丹参口崩片中冰片的含量

Determination of Borneol in Compound Salvia Orally Disintegrating Tablet by GC

合成了降冰片二烯衍生物&2-萘胺甲酰基-2,5-[2.2.1]-双环庚二烯（B）。研究了它在太阳光直接照射下的光异构化反应。

The norbornadiene derivative-2-naphthyl-carbamoyl-2,5 - [ 2.2.1 ] - bi-cycloheptadiene ( B ) was synthesized and its photoisomerization under sunlight studied .

毛细管GC法测定烧伤喷雾剂中冰片的含量

Determination of Borneo Camphor in Empyrosis Spray by GC

二苯基冰片基甲醇经元素分析、MS、IR和~1H-NMR加以鉴定。

The diphenyl bornyl carbinol is identified by element analysis , MS , IR and 1H-NMR .

以伊文氏蓝（Evan'sblue）对脑组织的蓝染程度为判别指标，观察了家兔、大鼠灌服冰片后，伊文氏蓝对脑组织的着色。

After the rabbits and rats were fed with borneol , their brain tissue was stained with Evan 's blue .

冰片iv2.0mg·kg~（-1）能够减轻小鼠全血凝块重量（P＜0.01或P＜0.05）。

Kg ~ ( - 1 ) ( P0.01 or P0.05 ) . Whole blood clot of mice was cut down with Borneol iv 2.0 mg ?

冰片对大鼠缺血再灌注模型视网膜单链糖蛋白ICAM-1表达的影响

Effect of Borneol on ICAM-1 Expression in Retina of Ischemia-reperfusion Rat Model

复方丹参片中冰片的GC-MS法测定

Determination of Borneol in Compound Salvia Tablets by GC-MS

冰片对脑外伤脑血管内皮细胞iNOS表达的影响

The influence of borneol to the iNOS of brain microvascular endothelial cells

合成冰片对大鼠海马神经元GABAA受体介导电流的作用

Effect of Borneolum Syntheticum on GABA_A receptor-mediated current in rat hippocampal neurons

由降冰片二烯经化合物（4）制备15-甲基前列腺紊F（2α）已有报导。

Synthesis of 15-methyl PGF_ ( 2 α) from compound ( 4 ), which in turn , was prepared from norbornadiene is reported .

SPE-HPLC研究冰片对三七皂苷R1药代动力学影响

Investigation on the effect of borneol on the pharmacokinetics of notoginseng R_1 in rabbits by SPE-HPLC

Ca～（2+）、NO、ICAM-1对冰片促血脑屏障开放作用的影响

The influence of Ca ~( 2 + )、 NO 、 ICAM & 1 on the function of borneol promoting BBB s opening

以5-降冰片烯-2,3-二酸酐（NA）和甲醇为原料，正交试验法合成了5-降冰片烯-2,3-二羧酸单甲酯（NE），并对产物结构进行了表征。

5-norbornene-2,3-dicarboxylic acid monomethyl ester was prepared by using 5-norbornene-2,3 - ( dicarboxylic ) anhydride and methanol as raw materials and toluene as solvent .

α-蒎烯BPO催化法合成冰片的动力学研究

The method of synthesizing borneol with BPO catalyst

给药方式的研究表明：冰片通过ig和iv方式给药均能增加DDP在小鼠脑中的含量。

The administration study showed that the medication of ig & iv both increased the contents of DDP in mice brain .

目的观察不同浓度的川芎嗪、冰片在鼻腔灌流时，对鼻腔总蛋白（TP）和乳酸脱氢酶（LDH）释放，以及鼻黏膜形态的组织病理学影响。

OBJECTIVE To study the effects of the ligustrazine , synthetic borneol on the TP , LDH and mucosa morphous when perfusing nasal cavity .

产物的NMR分析证明所合成产物分子中降冰片烯环上双键未参与聚合反应。

NMR characterization of the synthesized products shows that the double bond in the norbornene rig of the product polymers is not affected by the ATRP conducted .

方法用ICPAES测量给药后KM小鼠和Wistar大鼠脑中Pt2+的浓度。结果冰片对DDP透过BBB具有促进作用。

METHODE The ICP-AES was used to detect the concentration of Pt 2 + in the brains of KM mice and Wistar rats .

同时应用小鼠骨髓嗜多染红细胞微核（MN）试验观察染色体畸变情况，对新来源天然冰片和合成冰片的致突变性在基因及染色体水平上进行综合判定与比较。

Relying on the above methods , the mutagenicity of new source Natural Borneol and Synthetic Borneol was comprehensively compared and analyzed in the genic and chromosomal level respectively .

合成冰片与松节油中■-蒎烯的GLC分析

GLC analysis of synthetic borneol and ■ - pinene in turpentine oil

冰片对三七皂苷R1和人参皂苷Rg1，Re家兔组织分布的影响

Effect of borneol on the tissue distribution of notoginseng R1 , ginsenoside Rg1 and Re in rabbits

合成冰片的比旋度α30D为-17.3°～-2.3°。

The specific rotation of synthetic borneol is - 17.3 °~ - 2.3 ° .

我们将带有聚乙二醇侧基的降冰片烯衍生物单体进行表面聚合，在硅片上得到了聚乙二醇（PEG）接枝的新型梳型聚合物功能薄膜，并考察了该材料的抗蛋白吸附性能。

Norbornene derivative monomers with polyethylene glycol ( PEG ) modified side chains were polymerized from silicon surface . The protein resistance of the PNb-PEG surface was studied .

经枕大池注入肺炎球菌悬液建立脑膜炎模型，以冰片作为开放BCB的制剂。

The experimental meningitis was infected by the injection of pneumococci into the cistern magna .

本文介绍了适用于RTM成形聚酰亚胺材料的研究进展，主要包括采用降冰片烯酸酐（NA）封端的PMR聚酰亚胺树脂和使用苯乙炔基封端剂合成的聚酰亚胺树脂。

RTM polyimide materials mainly including the PMR polyimides end-capped with nadic anhydride ( NA ) and phenylethynyl end-capped polyimides were reviewed in this paper .

随着冰片含量增加，丹参脂溶性成分的Papp明显增大；

With increasing dosages of borneol , the Papp increased obviously .

降冰片烯（Norbornene）及其衍生物具有同以上系统相似的自愈合功能。

Norbornene ( NB ) and its derivates have a similar self-healing function .