先天性尿道下裂

目的了解雄激素受体基因（CAG）n重复多态性与先天性尿道下裂的形成的关系。

Objective To comprehend the relationship between ( CAG ) n polymorphism in androgen receptor gene and the formation of congenital hypospadias .

目的探讨不同术式对445例不同类型先天性尿道下裂患儿的手术治疗效果。

Objective To evaluate the choice of different operative procedures and how to improve the success rate by review the treatment for 445 cases of different congenital hypospadias .

先天性尿道下裂患者SRY基因的检测

A Study on Detection of SRY Gene in Hypospadias Patients

方法采用PCR方法对42例先天性尿道下裂患者外周血白细胞进行SRY基因检测。

Methods SRY gene of peripheral blood leukocytes was detected by means of PCR in 42 cases of hypospadias in children .

方法：通过受体的放射配基结合分析，对28例不同程度的先天性尿道下裂患儿外生殖器皮肤细胞内的AR、ER的表达及细胞内的分布进行了测定。

Methods : AR and ER expression and its distribution in the preputial cells of 28 cases with different types of hypospadias were examined by radioligand binding assay ( RBA ) .

提高Duckett术式治疗尿道下裂治愈率的相关因素分析先天性尿道下裂与SRY基因关系的探讨

Factors related to successful repair of hypospadias with Duckett procedure Detection of SRY gene in hypospadias patients

成功建立了兔先天性尿道下裂模型。

We succeeded in establishing the rabbit model of congenital hypospadias .

横行岛状包皮瓣修复先天性尿道下裂20例临床分析

One-stage repair for 20 cases of boy hypospadias with horizontal preputial island flap

结论：使用非那雄胺可以诱导出稳定的雄性新西兰幼兔先天性尿道下裂模型。

Conclusion : The experimental model of hypospadias induced by finasteride is stable .

445例先天性尿道下裂的治疗

Treatment for 445 Cases of Congenital Hypospadias

目的探讨小儿先天性尿道下裂行尿道成形术术后的护理问题和措施。

Objective To review and introduce the postoperative care for children with congenital hypospadias after urethroplasty .

结果：先天性尿道下裂合并泌尿系统畸形的发生率高达21。

Results : The morbidity of associated anomalies in cases of hypospadias was as high as21.1 % .

游离包皮内板一期尿道成形术修复先天性尿道下裂&附54例分析

Analysis of one stage urethroplasty using free inner plate of prepuce for the treatment of geneogenous hypospadias

结论：各种类型先天性尿道下裂尿道成形失败后，可用膀胱粘膜移植尿道成形，效果良好。

Conclusions : Bladder mucosa graft urethroplasty is a feasible procedure in patients who had unsuccessful urethroplasty previously .

1988年6月至1994年6月对20例18个月以下先天性尿道下裂患儿施行一期成形术。

From June 1988 to June 1994,20 infants less than 18 months old underwent one stage urethroplasty for hypospadias .

方法：先天性尿道下裂患者28例，采用包皮腹侧转移纵形带蒂皮管一期尿道下裂成形术治疗。

Method : 28 cases of hypospadias received one stage repair by tubularized longitudinal flap ventrally transferred from hood foreskin .

目的：总结双皮瓣法尿道成形一期手术治疗先天性尿道下裂的体会。

Objective : To summarize the experience in treatment of hypospadias using diplo ( preputial ) flaps technique by one-stage urethroplasty .

结论：帽状包皮腹侧转移纵形带蒂皮管一期尿道下裂成形术是治疗先天性尿道下裂简单、有效、可靠的手术方式。

Conclusion : One stage operation by tubularized longitudinal flap ventrally transferred from hood foreskin is a simple , effective and credible surgical method for hypospadias .

第一部分不同外科皮瓣修复尿道下裂的临床疗效评价目的：探讨先天性尿道下裂不同外科皮瓣的特点，评价其修复尿道下裂的临床疗效。

PART ONE ASSESSMENT OF CLINICAL EFFICACY OF DIFFERENT SURGICAL FLAPS FOR HYPOSPADIASObjective : To investigate the different characteristics and clinical efficacy of various surgical flaps for congenital hypospadias .

目的通过人工干预怀孕母鼠体内雄激素受体，造成雄性幼鼠先天性尿道下裂模型，探索造模所需的最佳给药时间及剂量。

Objective Through artificially interfering the pregnant mice 's androgen receptors to make their male whelps suffer congenital hypospadias , and to optimize the conditions for medication time and dosage .

先天性阴囊畸形合并尿道下裂分型的探讨

Investigation on classification of congenital scrotum malformation with hypospadias