亲核反应

并且发现，氯氰菊酯在水溶液中的水解速率远比马拉硫磷慢，但pH和温度对二者的水解效应相似，证明氯氰菊酯的水解机制与马拉硫磷相同，属于亲核反应。

AS the hydrolysis rate of cypermethrin was increased with the raising of pH and temperature as that of malathion , it proved that the hydrolysis mechanism of cypermethrin , the same as that of malathion , was nucleophilic reaction .

计算结果表明：DMB分子容易得到电子，且醛基上的碳原子是亲核反应的作用点。

The calculated results show that DMB is activity to get electron , and the carbon in the aldehyde group is the nucleophilic reaction site .

最后通过分子内SN2亲核反应法找到了一条高效构建N-糖链核心三糖的新路线，这也是迄今已报道的最简洁高效的路线。

A new highly convenient route for the core trisaccharide of N-glycans construction was found by the SN2 inversion method . And it is the most convenient route which has been reported until now .

进一步通过亲核反应速率的不同，又可以将半光氨酸、高半胱氨酸和谷胱甘肽区别开来。这样一个识别含巯醇基氨基酸反应型OFF-ON荧光探针，在医疗生物领域具有应用潜力。

Identification of three amino acids , and further by the type of the nucleophilic reaction rate , and can be open cysteine , homocysteine and glutathione distinction , such a reaction type OFF-ON fluorescent probe in the medical biological field has a very good application potential .

丹参酮ⅡA与乙胺的亲核反应

The Nucleophilic Reaction of Tanshinone ⅱ A with Ethylamine

主要研究内容如下：1、以氯甲基化聚苯乙烯为母体，与含氮的配体发生亲核反应制备了六种螯合树脂，并根据配体的性质分成杂环和直链配体树脂两个系列。

In this thesis , six kinds of chelating resins with heterocyclic and straight-chain ligands were prepared .

综述了近几年钌亚乙烯基络合物中间体α-碳的亲核反应。

This article reviews recent progress in nucleophilic reactions of the a - carbon in vinylidene ruthenium complexes .

经亲核反应、过滤、稀释、萃取和减压蒸馏等后处理手段，将2-（2，2，2-三氟乙氧基）硝基苯从粗品中分离出来。

Through the steps such as nucleophilic reaction , filtration , dilution , extraction and vacuum distillation , the 2 - ( 2,2,2-trifluoroethoxy ) nitrobenzene is separated from crude product .

β-过氧醇类化合物是一种多官能团化合物，具有非常活泼的过氧羟基和羟基基团，它们可以和许多缺电子基团发生亲核反应。

β - Hydroperoxy alcohols are a multi-functional group compounds , and have a very lively hydroxy peroxy and hydroxyl groups . They can react with many nucleophilic reagents having electron-deficient groups .

而当R为吸电子基团-CHO、-COCH3时，主要发生分子内氮原子上的亲核取代反应，产物为含氮的五员杂环化合物。

In contrast , electro-withdrawing groups CHO and COCH_ 3 on the attacking site will favor the intramolecular nucleophilic substitution of nitrogen and form 5-membered heterocyclic compounds .

卤代烷亲核取代反应的一种新机理&S（RN）1

A New Mechanism of Nucleophilic Substitution Reactions for Alkyl Halides & S_ ( RN ) 1

Vicarious亲核取代反应研究进展

Recent progress on Vicarious nucleophilic substitution reaction

提出自由基IPSO亲核取代反应机理。

A radical IPSO substitution mechanism is proposed .

芳香族硝基化合物与苯硫酚钠盐的亲核取代反应&自由基IPSO取代机理

Studies on the Reaction of Aromatic Nitro Compounds with Sodium Phenylthiolate & Radical IPSO Substitution Mechanism

在亲核取代反应中；无论按SN1历程还是SN2历程，烯丙式卤代烃的反应速度都是最快的。

In the substitution reaction of nucleophilic , whatever we use S_N1 or S_N2 reaction course , the rate of reaction is the most rapid .

最终产物的ee值与中间体α-羟基酮十分接近，表明在所发生的亲核取代反应中基本没有消旋化得现象发生。

The ee values of the final products were very close to those of α - hydroxy ketones , which indicated that no racemization occurred in the substitution .

方法应用小型回旋加速器，通过18O（p，n）18F核反应生产出18F离子，由亲核取代反应制备18F-FDG，并对所制备的18F-FDG注射液进行质量控制。

METHODS 18F-FDG was synthesized via nuclear reaction 18O ( p , n ) 18F on 18O-enriched water and nucleophilic substitution reaction by Tracerlab Mx FDG synthesis system .

这套客观的取代基常数用之于芳香亲核取代反应不比Miller从该反应系中求出的数值差。

This set of objective substituent constants can also be applied to aromatic nucleophilic substitution not any less adequately than that derived by J. Miller right from this very type of reactions .

水解反应的可能机理是SNl和SN2.双分子亲核取代反应立体化学问题释疑

The mechanisms of the hydrolysis were proposed to be unimolecular nucleophilic substitution and bimolecular nucleophilic substitution ( SN2 ) . On the Problem of Bimolecular Nucleophilic Substitution Reaction Sterochemistry

氢的替代亲核取代反应（VNS）是与硝基芳环的亲电反应、亲核反应不同的一种新反应。

Vicarious nucleophilic substitution ( VNS ) of hydrogen is a new type of reaction which is differ-ent from the usual electrophilic and nucleophilic reactions of the nitro arenes .

以磷酰氯为原料通过与手性仲胺的亲核取代反应高产率地合成了手性HMPA类似物。

The chiral HMPA analogues 1 and 2 were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride .

然后F-AQN-OPEG-OMe与奎尼丁的锂盐再进行亲核取代反应，以91.7%的产率得到新型手性配体QD-AQN-OPEG-OMe。

Then , QD-AQN-OPEG-OMe was synthesized in 91.7 % yield by reaction of F-AQN-OPEG-OMe with the lithium salt of quinidine .

核磁跟踪测试表明，HCCP和BPS进行的是双分子亲核取代反应（SN2），三乙胺（TEA）在反应中不仅作为缚酸剂，而且还起着活化BPS、促进亲核进攻的作用。

1H NMR monitor of the polycondensation showed that TEA acted as not only acid-acceptor but also catalyst to activate BPS for nucleophilic substitution . And condensation between HCCP and BPS followed a bimolecular nucleophilic substitution ( S_N2 ) pattern .

由于单分子亲核取代反应（SN1）经过了碳正离子中间体的历程，所以得到的产物是外消旋的。

In the reaction mechanism of unimolecular nucleophilic substitution ( SN1 ), it can produce carbocations which can easily lead to the racemization of the products .

进行了动力学研究，获得了反应活化能和各反应温度下的反应速率常数，同时研究结果表明烯丙基化反应级数为2，反应机理为SN2亲核取代反应。

The activation energy and rate constant of the allylation reaction was calculated in virtue of kinetic study . The kinetics study indicated that the allylation reaction of polyether was second order and its reaction mechanism was SN2 nucleophilic substitution .

氢键活化的苯环上C-F键的亲核取代反应研究亲核取代法制备壳聚糖6-OH固载环糊精衍生物

Study of Nucleophilic Substitution Reaction of C-F Bond on a Benzene Ring under Activation of Hydrogen Bond PREPARATION OF CHITOSAN IMMOBILIZED WITH β - CD AT C_6 POSITION BY A NUCLEOPHILIC DISPLACEMENT REACTION

苯甲酰氯亲核取代反应的热动力学研究

Study on the thermokinetics for nucleophilic substitution reactions of benzoyl chloride

离去基的电子效应在芳香族双分子亲核取代反应中的作用

The action of electronic effect of leaving groups on S _NA_r reactions

离子液体在亲核取代反应中的应用

The Use of Ionic Liquids in the Nucleophilic Displacement Reactions

四氢叶酸辅酶模型的合成及与氨类亲核试剂反应性能的研究

Synthesis of a tetrahydrofolate model and its reaction with nucleophiles