二氢杨梅素

黄酮及二氢杨梅素都能不同程度降低小鼠血清TC、TG、LDL-C、MDA含量，提高血清HDL-C含量及SOD活性，降低肝系数。

Tengcha flavones and DMY decreased serum TC , TG , LDL-C , malondiadehyde ( MDA ) contents and Liver coefficient , increased HDL-C levels and the activities of SOD distinctly .

进一步利用SephadexLH-20层析柱进行分离纯化，制得的黄酮纯度达74.40%，二氢杨梅素含量达67.12%。

The purity of flavones with further purification by Sephadex LH-20 was 74.40 % and the content of DMY was 67.12 % .

在此基础上，建立了高效液相色谱法测定二氢杨梅素的操作条件。色谱柱为Symmetry300~（TM）C（18）3.5×150mm；

At the base of that , the operation condition of HPLC method to determine DMY are immobile phase was Symmetry 300 ~ ( TM ) C_ ( 18 ) 3.5 × 150mm ;

二氢杨梅素酯化物在极性溶剂中清除DPPH自由基和H2O2的能力比二氢杨梅素低，酯化物的抗氧化活性随着酯化程度的增加呈下降趋势；

The scavenging effects of DMYL on DPPH free radicals and H2O2 in polar solvents were both weaker than those of DMY , decreasing with the increase of esterification degree .

二氢杨梅素在水中的溶解度随温度变化非常大，100℃溶解度为1.5900g/100g水，25℃下溶解度为0.0691g/100g水。

The solubility of DMY in water changed large with the changes of temperature , 1.5900g/100g water at 100 ℃ and 0.0691g/100g water at 25 ℃ respectively .

最佳提取工艺条件参数为：乙醇预处理时间为15h，茶与乙醇的料液比为1∶8，加热时间为30min，在此条件下二氢杨梅素的提取率为34.23%。

The most suitable conditions for the extraction was that the soaking time of ethanol was 15 h , the duration of extraction was 1:8 , and the heating time was 30 min. The extracting rate of MAE was 34.23 % in this conditons .

分别研究了影响二氢杨梅素提取收率的几个因素。

Some factors related to the extract rate of dihydromyricetin are investigated .

二氢杨梅素铜配合物的合成及其与牛血清白蛋白的相互作用

Synthesis and Interaction of DMY-Copper Complex with BSA

目的：研究二氢杨梅素对糖耐量异常大鼠氧化和非酶糖基化的影响。

To study the influence of dihydromyricetin on the oxidation and non-enzymatic glycosylation in impaired glucose tolerance rats .

结果表明：与高脂模型组比较，二氢杨梅素对高脂血症小鼠体重有明显减轻作用；

The results showed , compared with the hyperlipidemia control group , DMY reduced the weights of mice significantly ;

用月桂酰氯对二氢杨梅素的羟基进行酯化，合成了二氢杨梅素月桂酸酯。

Hydroxy in dihydromyricetin ( DMY ) was esterified with lauroyl chloride and dihydromyricetin laurate ( DMYL ) was synthesized in this investigation .

采用“增温溶解，保温过柱，温水解吸”的方法对显齿蛇葡萄中的二氢杨梅素进行提制研究。

The method of " dissolve with heat , flow with the same temperature , elute with warm water " was used in this paper .

为了进一步提高二氢杨梅素功效和应用范围，对其进行化学结构修饰已成为当前研究热点。

In order to further improve the efficacy and application scope , People has modified the chemical constitution of DMY , which has become the focus of present research .

二氢杨梅素在乙醇、甲醇、正丙醇、异丙醇、乙二醇、丙二醇、丙酮、乙酸乙酯、乙酸以及正己烷等常用有机溶剂中的溶解度较高；

Thesolubility of DMY in water , ethanol , methanol , propanol , 2-propanol , ethylene glycol , propanediol , acetone , ethyl acetate , acetic acid and n-hexane are high .