乙酰甲胆碱

结果：乙酰甲胆碱激发后过敏组小鼠H较对照组显著增高。

Results : H was significantly higher in allergic mice than in control animals after methacholine challenge .

乙酰甲胆碱激发试验研究哮喘青春期自然缓解者的气道反应性

Study on bronchial responsiveness by methacholine challenge test in asthmatics with automatic remission during puberty

2a后复查了乙酰甲胆碱激发试验70%为阳性，乙酰甲胆碱浓度与气道高反应性呈负相关；

After 2 years , 70 % of the patients had positive results of the bronchial methacholine chloride provocation . Methacholine chloride concentration was negatively related to hyperresponsiveness of bronchus .

Acetamide-45抑制组胺和乙酰甲胆碱引起的豚鼠离体气管收缩

Acetamide-45 inhibits histamine - and methacholine-induced contraction of isolated guinea pig trachea

方法：在卵白蛋白（OA）致敏的大鼠，用1%OA气雾攻击后，以计算机辅助技术测定气道管壁面积、支气管周围嗜酸粒细胞数量以及对乙酰甲胆碱（MCh）的反应性。

METHODS : In ovalbumin ( OA ) - sensitized rats , bronchiole wall area , eosinophils around bronchi , and the responses to methacholine ( MCh ) aerosol were measured after 1 % OA aerosol challenge with computer-assisted techniques .

结果表明：梭曼对呼吸中枢作用最强、沙林次之、VX最弱且更似乙酰甲胆碱。

The results indicated that the inhibitory effect of Soman on the medullary respiratory centre was much stronger than that of Sarin , while VX was the weakest of three inhibitors .

肺Micro-CT影像和Hounsfield单位的直方图也显示乙酰甲胆碱激发后过敏小鼠与对照相比容积丢失增高。

Micro-CT images and histograms of Hounsfield units from the lungs also showed increased volume loss in the allergic mice compared with control animals after methacholine challenge .

急性哮喘小鼠模型的确认是通过评估行为变化，哮喘症状，用乙酰甲胆碱激发行肺功能测试，BALF的炎症细胞，IL-17水平变化和肺组织病理。

The acute asthma model was confirmed by evaluating the behavioral changes and asthmatic symptoms occurred in mice and through the pulmonary function test with methacholine provocation , level of inflammatory cells and IL-17 in BALF and lung tissue histology .

目的：探讨新型抗变态反应药N-对氟苄基-3-[（N-4-吡啶）-乙酸胺]-吲哚-45（acetamide-45）对组胺和乙酰甲胆碱引起的豚鼠离体气管收缩的影响。

To investigate the effects of the new antiallergic agent N - ( pyridin-4-yl ) - ( indol-3-yl ) acetamide-45 ( acetamide-45 ) on histamine - and methacholine-induced contraction of the isolated guinea pig trachea .

乙酰甲胆碱支气管激发试验安全性高，未见严重不良事件。

Methacholine bronchial provocation test has high safety , no severe adverse reaction is recorded .

结论（1）乙酰甲胆碱支气管激发试验是诊断不典型哮喘的有效手段；

Conclusions The methacholine provocation test is effective in diagnosing the asthmatic patients with atypical symptoms ;

白三烯受体拮抗剂对乙酰甲胆碱支气管激发试验剂量-反应曲线参数的影响

The Effect of Leukotriene Antagonist on the Parameters of Dose-response Curve Obtained after Methacholine Challenge Test

乙酰甲胆碱在婴幼儿支气管激发试验中的安全性分析

Safety of methacholine in bronchial provocation test for infants Fostering Innovation and Creativity among Employees in Workplace

不同浓度乙酰甲胆碱介导犬心房颤动的电生理标测和射频消融

Experimental study of electrophysiological mapping and radiofrequency ablation on atrial fibrillation mediated by different concentrations of methacholine in dogs

方法对临床肺功能、支气管扩张试验不能确诊的病人，用乙酰甲胆碱行支气管激发试验，明确诊断。

Methods The mechacholine provocation tests were applied to patients whom couldnt be diagnosed by lung function test and bronchiectasis test .

结果显示：大豆异黄酮灌胃给药，能显著抑制乙酰甲胆碱诱导的致敏小鼠气道高反应性。抑制灌洗液中的总的炎症细胞和嗜酸性粒细胞增加。

Oral administration of soy isoflavone significantly reduced ovalbumin-induced airway hyperresponsiveness to intravenous methacholine , and inhibited ovalbumin-induced increases in eosinophil counts .

结论短期应用白三烯受体拮抗剂可改善哮喘患者乙酰甲胆碱支气管激发试验剂量-反应曲线参数。

Conclusion Short term use of Zafirlucast in asthmatic patients could improve the parameters of dose response curve obtained after the methacholine challenge test .

方法：在为期3年的前瞻性研究中，对769名暴露于高分子量变应原的学徒工进行乙酰甲胆碱激发试验和系列的问卷调查。

Methods : A3 year prospective study involving methacholine challenge tests and serially administered questionnaires was undertaken in769 apprentices exposed to high molecular weight allergens .

目的探讨乙酰甲胆碱激发试验剂量-反应曲线参数的测定方法与临床意义。

Objective To investigate the clinical value in the measurement of parameters of the dose response curve ( DRC ) obtained after the methacholine challenge test .

本文对12例哮喘患者吸入氢溴酸山莨菪碱（654-2）后进行乙酰甲胆碱支气管激发试验，观察该药对支气管高反应性的影响，并与硫酸阿托品相比较。

Anisodamine ( 654-2 ) was administered by inhalation to 12 asthmatic patients , and bronchial hyper-reactivity was studied by methacholine provocation test . The results were compared with atropine sul-fate .

其激发机制与乙酰甲胆碱不同，因而在哮喘发病机理和治疗的研究中有不同的意义。

That the mechanism of propranolol challenge differs from that of methacholine challenge , so there is different significance between the two challenges in the mechanism and the research of treatment of asthma .

胆碱酯类（乙酰胆碱、氨甲酰胆碱和乙酰甲胆碱）及毒扁豆碱对肝片形吸虫呈抑制作用而对鸡蛔虫则呈兴奋作用。

The rhythmical activity of the liver fluke was inhibited and those of chicken roundworm was stimulated by choline esters ( acetylcholine , carbacholine and acetyl - β - methylcholine ) and eserine .