中性粒细胞减少

结论SAA患者是并发感染的高危人群，影响感染的主要因素是中性粒细胞减少；

Conclusion SAA patients were at high risk of infection which was significantly associated with severe neutropenia .

侵袭性真菌感染（IFI）是恶性血液病、长时间中性粒细胞减少或造血干细胞移植后患者重要的发病和死亡原因之一。

Invasive fungal infection ( IFI ) is an important cause of morbidity and mortality in patients with hematologic malignancy , prolonged neutropenia , or after hematopoietic stem cell transplant .

P患者的资料。药物性中性粒细胞减少症患者病因分析及对策

P were analyzed retrospectively . The causes of medicine-induced neutrophilic granulocytopenia and the countermeasures

C组中性粒细胞减少的发生率高于B组，两组间差异有显著性（P<005）。

Neutropenia was more common with C than with B ( P < 0.05 ) .

慢性特发性中性粒细胞减少症患者血清G-CSF水平测定及其意义

Determination of Serum Granulocyte Colony-Stimulating Factor Level in Patients with Chronic Idiopathic Neutropenia and Its Significance

两组主要不良反应均为中性粒细胞减少，A组和B组Ⅲ、Ⅳ度中性粒细胞减少发生率分别为53.1%和44.4%，差异无显著性（P>0.05）。

The incidence of grade ⅲ - ⅳ neutropenia in group A and group B was 53.1 % and 44.4 % respectively . The difference between the two groups was not significant ( P > 0.05 ) .

国产rhG-CSF预防乳腺癌化疗后中性粒细胞减少症的应用策略

Study on the strategies of domestic rhG-CSF in preventing neutropenia caused by breast cancer chemotherapy

联合应用抗生素对中性粒细胞减少期感染的经验性治疗结论：在ICU院内感染流行病学监测指导下，头孢吡肟可作为经验性治疗院内细菌感染的首选抗生素之一。

Antibiotic Combined Therapy as an Empirical Treatment for Febrile Patients with Neutropenia CONCLUSION : Cefepime is an effective antibacterial agent for nosocomial infection .

与P组对比，制模后2hT组肾组织中中性粒细胞减少（P<0001），12h后肾组织中性粒细胞浸润明显减少（P<0001），2h及12h肾组织学损害均明显减轻（P<005）。

Contrast with group P , the renal pathological changes and neutrophils infiltration were alleviated significantly ( P < 0.05 ) at 2 h and 12 h in group T.

检测慢性特发性中性粒细胞减少症（CIN）患者血清粒细胞集落刺激因子（G-CSP）水平并探讨其意义。

To investigate the serum granulocyte colony-stimulating factor ( G-CSF ) level in patients with chronic idiopathic neutropenia ( CIN ) and analyze its clinical significance .

泊沙康唑在体外具有广谱抗真菌活性，对于高危HSCT受者以及持续中性粒细胞减少患者侵袭性真菌感染的预防可能有重要作用。

Posaconazole has a broad spectrum of activity in vitro and a potentially key role in antifungal prophylaxis in high-risk HSCT recipients and during prolonged neutropenia .

背景与目的：重组人粒细胞集落刺激因子（rhG-CSF）是防治肿瘤化放疗引起的中性粒细胞减少症的有效药物，但半衰期短，需每日给药。

BACKGROUND & OBJECTIVE : Recombinant human granulocyte colony-stimulating factor ( rhG-CSF ) is effective in the prophylaxis and management of chemotherapy-induced neutropenia , but requires daily administration because of its short half-life .

其剂量限制毒性（DLT）为中性粒细胞减少和腹泻，肝肾功能下降会降低最大耐受剂量（MTD）。

The dose limiting toxicity ( DLT ) o f it was neutropenia and diarrhea . Its maximum tolerance dose ( MTD ) may be reduced by elevated liver or kidney function .

全组共化疗152周期，无化疗相关死亡患者，主要不良反应为消化道反应和骨髓抑制，III-IV度呕吐12.5%，III-IV度腹泻5.0%，III-IV度中性粒细胞减少17.5%。

A total of 152 cycles were administered . There was no death associated with chemotherapy . Major toxicities were gastrointestinal toxicity and myelosuppression with grade III-IV vomiting in 12.5 % , grade III-IV diarrhea in 5.0 % , grade III-IV neutropenia in 17.5 % .

感染和中性粒细胞减少症都没有增加。

There was no increase in infections or neutropenia with rituximab .

发热性中性粒细胞减少患者细菌谱及药敏分析

Bacterial spectrum and antimicrobial susceptibility pattern in in febrile neutropenic patients

不良反应主要为中性粒细胞减少、恶心、呕吐等。

The main toxicity was neutropenia , nausea and vomiting .

成人慢性特发性中性粒细胞减少症的病因探讨

Analyze on 61 patients with adult chronic idiopathic neutropenia syndrome

最常见的严重不良反应包括中性粒细胞减少和肺炎。

The most common serious adverse reactions included febrile neutropenia and pneumonia .

恶性肿瘤患者中性粒细胞减少并感染的临床分析

Clinical analysis on neutropenic malignent tumor patients with infection

抗生素用于治疗发烧和中性粒细胞减少症；

Antibiotics are used to treat fever and neutropenia ;

不同病毒和细菌感染儿童中发现的一过性和慢性中性粒细胞减少症

Transient and chronic neutropenias detected in children with different viral and bacterial infections

哌拉西林-三唑巴坦治疗中性粒细胞减少症发热的疗效观察

Efficacy of piperacillin-tazobactam in the treatment of febrile neutropenia

小儿白细胞及中性粒细胞减少症331例相关因素分析与探讨

Study on analysis of related factors of leukocytopenia and neutropenia in 331 childish patients

最主要的副反应包括：血小板减少症、中性粒细胞减少症、胃肠道反应及甲状腺功能减低症。

The main side effects include thrombopenia , neutropenia , gastrointestinal tract response , and hypothyroidism .

结果：一般出现2～3级中性粒细胞减少，1～3级的粘膜毒性。

Results : There were grade 2 ~ 3 neutropenia , grade 1 ~ 3 mucositis .

“嗜中性粒细胞减少症”是指一种中性粒细胞浓度低于正常值的疾病。

" Neutropenia " is the term for a decrease below normal in the concentration of neutrophils .

国产与进口重组人粒细胞集落刺激因子治疗化疗后中性粒细胞减少比较

Comparison between effects of domestic and imported recombinant human granulocyte colony_stimulating factor in treating neutropenia after chemotherapy

抗菌药物联用治疗发热性中性粒细胞减少症血液肿瘤患儿的临床研究

Ceftazidime Alone or with Vancomycin in Treatment of Febrile Neutropenia in Children with Cancers : A Clinical Study

两组在贫血、中性粒细胞减少、神经毒性和肾毒性方面差异均无显著性。

There was no apparent difference between both groups in terms of anemia , neutropenia , neurotoxicity and nephrotoxicity .