肝脏纤维化

结果表明，PLD能较好地反映肝脏纤维化的程度，对慢性轻度肝炎与慢性重度肝炎及慢性肝炎是否存在硬化的鉴别诊断有一定参考意义。

It was suggested that PLD can clearly indicate the extent of hepatic fibrosis , and it had an important reference significance on diagnosing whether severe or mild chronic hepatitis had cirrhosis .

方法2000年～2003年收治的56例慢性乙型肝炎患者接受IFNα1b治疗6个月，于治疗前及治疗3个月时分别检测外周血T淋巴细胞亚群及血清肝脏纤维化指标。

Methods 56 patients with hepatitis B hospitalized from 2000 ~ 2003 were treated with interferon α for 6 months , the peripheral blood T lymphocyte subsets and hepatic fibrosis indexes were checked before interferon α treatment and in the 3rd month of treatment .

目的：高脂饮食可诱导非酒精性脂肪肝病，其病程包括脂肪肝、非酒精性脂肪性肝炎（NASH）、肝脏纤维化和肝硬化。

PURPOSE : NASH including simple fat accumulation to nonalcoholic steatohepatitis and hepatocirrhosis .

磁共振弥散加权成像ADC值诊断兔肝脏纤维化模型病理变化

Diagnosis of liver pathologies based on apparent diffusion coefficient of magnetic resonance diffusion-weighted imaging in a rabbit model of liver fibrosis

为自动获取肝脏纤维化定量分析指数&计算机形态学评分（CM评分），提出一种肝脏病理切片图像的分割方法。

To automatically obtain the quantitative index of the liver tissue fibrosis , or computer morphometry ( CM ) score , an approach is proposed to segment liver pathological sections .

用四氯化碳诱发大鼠出现肝脏纤维化，采用ELISA方法检测大鼠血清和肝组织匀浆中透明质酸（Hyaluronate，HA）的含量，并分析HA与肝组织病理改变之间的关系。

Liver cirrhosis was induced in rats with carbon tetrachloride . Hyaluronate ( HA ) levels were measured in both serum and liver homogenate using ELISA .

结论血清PⅢP、CⅣ和HA水平均是反映肝脏纤维化程度的良好指标，有较好的诊断价值，三者联合检测更能准确地判断肝纤维化。

Conclusions Serum P ⅲ P 、 C ⅳ and HA are valuable in assessing the extent of fibrosis in liver , and it will be a better way of diagnosing liver fibrosis to detect them together .

然后用共轭梯度算法改进BP神经网络，基于该网络与纹理特征计算肝脏纤维化的程度，并利用形状特征计算肝左叶钝化的程度；

Then , the degree of liver fibrosis is calculated according to its texture and the improved BP neural network by conjugate gradient algorithm , and the passivation of left liver leaf is calculated according to its shape characteristics .

结论在大鼠CCl4肝纤维化形成过程中，功能性瘦素受体的表达在肝损伤早期即明显增加，并随纤维化程度加重而逐步升高，从而促进肝脏纤维化的发生。

Conclusion In the process of the hepatic fibrosis induced by CCl_ ( 4 ) in rats , expression of OB-Rb was elevated from the early stage and correlated with fibrosis stage positively , aggravating the fibrosis .

目的研究IFNα治疗慢性乙型肝炎患者早期阶段外周血T淋巴细胞亚群及血清肝脏纤维化指标的变化，判断这些指标早期预测IFNα疗效的价值。

Objective To study the change of peripheral blood T lymphocyte subsets and hepatic fibrosis indexes in the early stage of interferon α treatment in patients with chronic hepatitis B , and to detect the value of these indexes in predicting the curative effect of interferon α treatment early .

超声背向散射积分对肝脏纤维化诊断价值的初步研究

Study of Ultrasonic Integrated Backscatter in Patients with Hepatic Fibrosis

肝脏纤维化血清标志物与肝脏病理的对照研究

Comparative studies of serum marker substances of liver fibrosis and liver pathology

目的：研究实验性大鼠肝脏纤维化进程中瘦素表达的变化。

Objective : To study the leptin expression in rat hepatic fibrosis .

超声波检查对肝脏纤维化分期的诊断价值

Diagnostic value of ultrasonic examination in patients with different stages of liver fibrosis

视黄醇脂对慢性酒精性肝病患者肝脏纤维化的抑制作用

Effect of vitamin A on hepatic cirrhosis in patients with chronic alcoholic liver disease

实验性肝脏纤维化瘦素表达的变化

Expression of Leptin in Liver Fibrosis of Rats

肝脏纤维化指标的检测与分析

The test and analysis of liver fibroid indexes

大剂量活血化瘀中药治疗肝脏纤维化的临床观察

Clinical observation on high-dose Herbs for Promoting Blood Circulation to Remove Blood Stasis in treatment of liver fibrositis

因此，乙型肝炎病毒慢性感染导致的肝脏纤维化、肝硬化甚至肝细胞肝癌仍然是基础和临床研究的热点。

Therefore , liver fibrosis , liver cirrhosis and hepatocellular carcinoma are the hot points of basic and clinical research .

背景各种病因所致的慢性肝实质炎症、坏死可引起持续性纤维结缔组织增生，一旦超过纤维的降解即可导致肝脏纤维化，弥漫性肝纤维化同时伴有肝小叶结构的被破坏和肝再生结节则形成肝硬化。

Background : The chronic inflammation and necrosis of liver parenchyma caused by any kind of pathogeny can arouse durative hyperplasia of fibril connective tissue , once the hyperplasia exceeds the degradation liver fibrosis will occur .

超声诊断除了受主观性和诊断经验等人为因素影响外，检测频率、机器参数的设置等成像条件的变化也会对图像产生很大的影响，因而使肝脏纤维化的量化分析受到很大限制。

Ultrasound diagnosis has a lot of restricted application in liver fibrosis quantitative analysis , because ultrasound image conditions such as scanning frequency , machine settings can influence the ultrasound images besides its subjective and experience-based characteristic .

随放疗剂量增加，肝静脉闭塞、肝脏纤维化及胆管损伤逐渐加重；同一肝脏放疗后，照射高剂量区较低剂量区及非照射区放射性肝损伤改变略重。

Because of the radiation dose increased , the venous occlusive disease , hepatic fibrosis and bile duct injury more serious . The high dose area and low dose area are serious than non-radiation area in the same liver after radiotherapy .

原发性肝癌与乙型病毒性肝炎（viralhepatitistypeB，简称乙肝）关系密切，特别是转为慢性肝炎后肝脏的纤维化是原发性肝癌的发病基础。

There is a close relationship between the primary hepatic cancer and the viral hepatitis type B. Especially the liver fibrosis is the foundation of PHC after it turn to chronic hepatitis .

合并症AIH影响肝脏的纤维化水平；

The complication-AIH would influence over Ishak fibrosis score .

小鼠肝脏局部纤维化的实验性研究

Experimental study of the local fibrosis on the mouse liver

肝脏的纤维化是各种慢性肝脏疾病向肝硬化发展的主要中间环节。

Hepatic fibrosis is the meddle stage of hepatic cirrhosis developed from varied kinds of chronic hepatic disease .

电镜检查显示模型组大鼠肝脏有纤维化性变化，海马脑片的神经元有趋向死亡性变化。

Moreover , ultrastructural examination by electron microscopy showed that the pathological changes of hepatic fibrosis in liver , the dying signs of neurons in hippocampus of rats in model group were observed .

患者发病后会导致胆管阻塞和胆汁淤积，造成特异性的胆管上皮细胞损伤，从而引发肝脏的纤维化，最后演变为肝硬化和肝功能衰竭，严重威胁患者的生命。

After onset , the following symptoms show up : biliary obstruction and cholestasis , biliary epithelial cells injury , liver fibrosis , and ultimately , cirrhosis and liver failure , which seriously threaten patients ' lives .

目的探讨活化CD4+淋巴细胞及HBeAg与慢性乙型肝炎肝脏损伤及纤维化的关系。

Objective It is to discuss the relationship between activation CD4 + lymphocyte and HBeAg with hepatic injury and fibrosis in chronic type B hepatitis .

慢性肝脏疾病肝纤维化非创伤性诊断模型的研究

Research of non-invasive diagnosis model of fibrosis in chronic liver disease