细胞毒素

IL-4细胞毒素对垂体腺瘤生长及其激素分泌的靶向治疗作用

IL-4 cytotoxin inhibits cell growth and hormone secretion of pituitary adenomas

目的了解广西眼镜蛇毒细胞毒素（CTX）的抗肿瘤作用。

Objective To study the antitumor effect of Guangxi cobra venom cytotoxin on malignant tumor .

Bcl-2对于由多种细胞毒素引起的细胞凋亡均有抑制作用。

Bcl-2 is able to inhibit apoptosis induced by variety of Cytotoxins .

斑点金免疫渗滤试验快速检测抗Hp细胞毒素相关蛋白A抗体

Dot immunogold filtration assay for anti Helicobacter pylori antibody

MTT法测定眼镜蛇毒细胞毒素的抗癌活性

MTT Assay for Determination of the Anticancer Activity of Cobra Venom Cytotoxin

有细胞毒素相关基因Hp与胃十二指肠疾病的关系初析

Preliminary investigation on the relationship between H Pylori strain with CagA gene and gastroduodenal diseases

坏死梭杆菌白细胞毒素基因SH片段的克隆与表达

Cloning and Expression of the Leukotoxin Gene SH from Fusobacterium necrophorum

眼镜蛇毒细胞毒素13诱导人脐静脉内皮细胞凋亡及对Bcl-2家族基因表达的影响

Cobra Cardiotoxin Induced Apoptosis in Human Umbilical Vein Endothelial Cells and Affected the Expression of Bcl-2 Family

眼镜蛇毒细胞毒素PLGA微球的制备及其抗肝癌作用研究

Preparation and Effect on Anti-hepatoma of PLGA Microspheres of Cobra Venom Cytotoxin

细胞毒素相关抗原（cagA）基因在中国人幽门螺杆菌中的分布及其临床意义

Distribution of H.pylori cagA gene among Chinese and its clinical significance

目的：在体外研究vero细胞毒素抗体的保护作用。

Objective : To study protection of antibody of vero cytotoxin in vitro .

目的从舟山眼镜蛇毒中分离纯化细胞毒素（CTX），并鉴定其理化性质。

Objective To isolate and purify cytotoxin isoforms from Naja atra and further appraise its properties .

目的建立定量检测幽门螺杆菌（Hp）细胞毒素相关蛋白基因A（cagA）的方法。

Objective To create a quantitative assay for cytotoxin associated gene A ( cagA ) positive Helicobacter pylori ( Hp ) .

制备眼镜蛇毒细胞毒素PLGA微球，研究其表征及体外释药性质；3。

To prepare PLGA microspheres of cobra venom cytotoxin and study its characterization and characteristics of in vitro release ; 3 .

TLRs激动剂在抗癌免疫疗法中可用作免疫调节剂或细胞毒素的药物。

TLRs agonists are used as immunomodulators ( immunoadjuvants ) and cytotoxic drugs in cancer immunotherapy .

而志贺毒素系STEC所产生的一种蛋白质性细胞毒素。

Stx is a protein cytotoxin produced by Shiga toxin E.coli .

目的：研究广西人上消化道疾病患者幽门螺杆菌（HPylori）细胞毒素相关蛋白（cagA）基因的阳性率，从而明确广西人群感染HPylori菌株的毒力状况。

AIM : To study the positive rate of Helicobacter pylori ( H pylori ) cagA gene of strains and the virulence of H pylori infecting patients in Guangxi , China .

背景：空泡形成细胞毒素A（VacA）是幽门螺杆菌（H.pylori）的重要致病因子，研究VacA的致病机制有助于进一步明确H。

Background : Vacuolating cytotoxin A ( VacA ) is an important pathogenic factor of Helicobacter pylori ( H.pylori ) .

目的探讨儿童幽门螺杆菌（Hp）细胞毒素相关基因A（cagA）的流行情况，分析其与胃十二指肠疾病的关系。

Objective To investigate the distribution of helicobacter pylori ( Hp ) cytotoxin-associated gene A ( cagA ) and their association with gastric duodenal diseases in children .

运用水油提、盐析及凝胶过滤色谱法对幽门螺杆菌YC－11株所分泌的形成空泡细胞毒素进行了提取。

The vacuolating Cytotoxin from Helicobacter pylori YC-11 was purified by using water-extracting , salt precipitation and gel filtration chromatographic fractionation .

用免疫印迹法检测Hp细胞毒素相关蛋白（CagA）、空泡毒素（VacA）、尿素酶（Urease）、鞭毛蛋白（Flagellin）及其亚型。

Western blotting was used to detect phenotypes of H. pylori Cytotoxin-associated protein ( CagA ), vacuolating cytotoxin ( VacA ), Urease , Flagellin and their sub-phenotypes .

目的调查产细胞毒素相关蛋白A的幽门螺杆菌（HP）在飞行员消化系统疾病中的感染状况，为飞行员消化系统疾病的诊治提供依据。

Objective To investigate the CagA positive strain of helicobacter pylori infecting among the digestive system disease of the pilots ' , it will be used to diagnose and cure accurately the digestive disease of the pilots ' .

目的克隆艰难梭菌（Clostridiumdifficile，C.d）细胞毒素B羧基末端功能区（CDB3）基因，并对其进行测序及生物信息学分析。

Objective To clone the C-terminal domain gene ( CDB3 ) of Clostridium difficile ( C.d ) and to perform sequencing and analyse the biological information .

幽门螺杆菌空泡形成细胞毒素A亚单位的克隆表达和P37抗体的制备

Expression and Cloning of Helicobacter pylori Vacuolating Cytotoxin A Subunits and Preparation of Antibody against P37

为了用X射线衍射方法测定细胞毒素的三维结构，我们尝试了生长适合于X射线工作的单晶体，用气相扩散方法得到了中华眼镜蛇细胞毒素的两种成分的四种晶型。

In order to determine the 3-dimensional structure oi cytotoxin by X-ray diffraction . We have tried to growth single crystals of cytotoxin suitable for X-ray work . Four crystal forms from two cytotoxin components ( Naja Naja Atra ) have been obtained by vapour diffusion method .

目的：分析广东地区细胞毒素相关基因（cagA）在幽门螺杆菌（H.pylori）中的分布情况及其与患者性别、年龄的关系；

Aims : To investigate the distribution of cagA gene of Helicobacter pylori ( H. pylori ) in Guangdong area and analyse the relationship between cagA and patients ' sex and age ;

60例肝癌、胃癌患者，41例慢性肝炎患者和103例普通体检者血清采用EIA法作CagA-HP-IgG抗体（产细胞毒素幽门螺杆菌抗体）测定。

CagA-HP-IgG detection was also performed in 60 cases of liver and gastric cancer , 41 cases of patients with chronic hepatitis and 103 healthy people .

方法采用免疫印迹法检测218例慢性浅表性胃炎（CSG）、慢性萎缩性胃炎（CAG）和胃癌（GC）患者血清细胞毒素相关蛋白抗体（CagA）。

Methods : The studied population comprised 218 patients with chronic superficial gastritis ( CSG ), chronic atrophic gastritis ( CAG ) and gastric cancer ( GC ) . CagA in serum were measured by immunoblotting .

目的探讨端粒酶RNA与胃粘膜幽门螺杆菌细胞毒素相关基因A（HpcagA）感染及增殖细胞核抗原（PCNA）表达的关系。

Objectives To explore the expression of telomerase RNA of gastric mucosa in patients with Helicobacter pylori cytotoxin associated gene A ( HpcagA ) infection and Proliferating cell nuclear antigen ( PCNA ) expression .

细胞毒素相关蛋白（CagA）、空泡细胞毒素（VacA）和尿素酶A、D、E抗体阳性者胃十二指肠粘膜无一例正常，中重度炎症发生率为949%～973%。

None of the children with antibodies against CagA , VacA , Urease A , Urease D and Urease E had normal gastroduodenal mucous membrance and the detection rate of gastroduodenal mucosal moderate severe inflammation was 94.9 % to 97.3 % .