染色体易位

采用PCR联合序列检测伴有或不伴有染色体易位的急性髓性白血病患者FLT3基因突变情况。

Using genomic PCR and sequencing , FLT3 / ITD mutation with or without chromosome translocation were examined in AML patients .

目的：探讨FLT3跨膜区内部串联重复（FLT3/internaltandemduplication，FLT3/ITD）突变和染色体易位与急性髓性白血病预后的关系。

AIM : To explore the relationship of FLT3 / internal tandem duplication ( ITD ) mutation and chromosome translocation with acute myeloid leukaemia ( AML ) prognosis .

13/17染色体易位纯合子猪群随机扩增多态性DNA指纹分析

Fingerprinting Analysis on the 13 / 17 Robertsonian Translocation Pig Population by RAPD

荧光原位杂交法分析中国医用诊断X射线工作者的染色体易位畸变

Chromosome translocations in Chinese medical X-ray workers analyzed by fluorescence in situ hybridization

结论FISH方法是分析X射线工作者染色体易位率进行剂量重建的可行方法。

Conclusion FISH is a feasible way to analyse chromosome aberrations of X-ray workers and reconstruct dose .

一些染色体易位可能影响NF-кB/IкB之间的平衡，从而参与白血病及淋巴瘤的发生。

Some chromosomal translocation may influence the balance of NF-K B / I K B family and play roles in leukemia and lymphoma .

黑麦-黑麦染色体易位率在0.48&52.78%之间，平均25.23%。鉴定的小麦-黑麦易位染色体涉及了黑麦的14条不同的染色体臂和小麦的A、B和D组染色体。

The 14 chromosome arms of rye and the A - , B - and D-genome chromosomes of wheat were involved in the wheat / rye translocations .

何杰金病中t（14；18）染色体易位与Bcl-2蛋白的表达

Chromosomal translocation ( 14 ; 18 ) and over expression of Bcl-2 protein in Hodgkin 's disease

SKY能够揭示常规核型分析法难以识别的染色体易位、重排的来源和一些marker的来源。

Especially SKY skill can disclose the origin of the chromosomal translocations and marker chromosomes which are not detected by CC .

目的分析滑膜肉瘤t（X；18）染色体易位断裂点基因组DNA序列特征，探讨其与滑膜肉瘤t（X；18）染色体易位发生的关系。

Objective To analyze the DNA sequence characteristics of translocation t ( X ; 18 ) genomic breakpoints and to study the mechanism underlying chromosomal translocation t ( X ; 18 ) in synovial sarcoma .

结论一步法RT-PCR技术检测染色体易位融合基因为临床RMS疑难病例的诊断和研究提供了有效技术手段；

Conclusion One-step RT-PCR assay for detection specific fusion gene provides a useful tool for confirmation of the diagnosis of RMS in diagnostically difficult cases and in retrospective studies .

目前，使用PGD技术，可以测试出许多种不同的疾病，包括非整倍体，单基因病和染色体易位等。

Currently , we are able to perform PGD for many genetic conditions including single gene disorders and chromosome abnormalities .

M-FISH技术检测辐射诱导染色体易位和双着丝粒畸变

Radiation-induced translocation and dicentric chromosome aberrations in lymphocytes of umbilical cord blood analyzed by multicolor FISH method

结果表明：这3种辐射剂量都可以高效诱导小麦-簇毛麦染色体易位，并且M1代种子发芽正常。

The results showed that all the three dosages of irradiation treatments were highly efficient for inducing wheat-H. villosa translocations , and the produced M1 seeds were viable to germinate .

利用一套5个豌豆染色体易位系和2个形态标记基因系chl7及Viola为标记材料，对豌豆卷曲突变基因curl进行了染色体定位。

A set of 5 chromosome translocation lines and two marker gene line chl-7 and Viola were used in testing the chromosome location of curl mutant gene in pea .

我们应用免疫组化染色和聚合酶链反应检测了11例慢性淋巴细胞白血病bcl-2基因表达和重排，结果发现所有病例均高度表达Bcl-2蛋白，1例有t（14,18）（q32，q21）染色体易位。

Overexpression of bcl-2 gene was found in all cases ; 1 of 11 cases had t ( 14,18 ) ( q32 , q21 ) translations .

结果：所有变异Ph染色体易位至少涉及3条染色体，并由标准Ph染色体易位t（9；22）（q34；q11）衍生而来。

Results : All variant Ph translocation involved at least three chromosomes and derived from a standard Ph translocation t ( 9 ; 22 )( q34 ; q11 ) .

急性早幼粒细胞白血病（APL）具有染色体易位t（15；17）而产生的特异的融合基因PML－RARα。

It is shown that the t ( 15 ; 17 ) translocation specifically associates with acute promyelocytic leukemia ( APL ) and forms the PML-RAR_ α fusion gene .

X线工作者的染色体易位率和总畸变率均明显高于对照组（P0.005）。

The frequencies of chromosome translocation and total aberrations in X-ray workers were higher than that of the control group ( P0.005 ) .

慢性粒细胞白血病急变伴t（3；21）（q26；q22）染色体易位受累基因的研究

Study of genes involved in chronic myeloid leukemia with t ( 3 ; 21 ) ( q26 ; q22 ) in blastic crisis

急性早幼粒白血病（APL）患者染色体易位t（15；17），导致产生该病特异的融合基因PML-RARa，由于PML外显子的使用差异而产生了融合基因异构体。

The chromosomal translocation of t ( 15,17 ) gives rise to the specific fusional gene PML-RARa in acute promyelocytic leukemia . The different using expression of PML exon produces the fusional gene isomeride .

本研究旨在探讨急性髓系白血病（AML）患者6；9染色体易位与DEK-CAN融合基因表达之间的关系及临床意义。

This study was aimed to explore the relationship of6 ; 9 chromosome translocation with DEK-CAN fusion gene expression in patients with acute myeloid leukemia ( AML ) and its clinical significance .

一个遗传了三代的染色体易位t（1；7）（1q42；7p22）家系

A Translocation with Chromosome t ( 1 ; 7 ) ( Iq42 ; 7p22 ) in Three Generations ot a Family

研究结果证实No.147是一个新的高抗白粉病的1BL/1RS小麦-黑麦染色体易位系，并对其产生的细胞学机制进行了分析。

The results showed that No. 147 was a new 1BL / 1RS wheat-rye chromosome translocation with high powdery mildew resistance derived from Weiling rye .

结果发现异常核型11例，其中染色体易位6例、2例47，XXY、3例大Y染色体。

Results : According to the patients ′ cytogenetics examination , it is found there are 11 cases abnormal chromosomal karyotypes , including 6 cases of chromosome translocation , 2 cases of 47 , XXY , 3 cases of big Y chromosome .

SSX基因家族由9个成员组成，其中ssx-1、SSX-2和SSX-4经常出现在滑膜肉瘤t（x：18）染色体易位的SYT-SSX融合基因中。

The SSX gene family is composed of 9 members , among which SSX-1 , SSX-2 , and SSX-4 have been found existing in SYT-SSX fusion gene resulting from the t ( X : 18 ) chromosomal translocation in almost all synovial sarcomas .

目的研究证实，95%的尤文肿瘤家族具有特异性t（11；22）（q24；q12）染色体易位，形成的EWS-FLI-1融合蛋白可以识别、结合一段特异基因序列（ACCGGAAGT）并且激活其下游基因表达。

Aims Previous studies have shown that EWS-FLI-1 fusion protein , formed by chromosomal translocation of t ( 11 ; 22 )( q 24 ; q 12 ) in 95 percent of Ewing 's sarcomas , can bind with special gene sequence ( ACCGGAAGT ), and has transcription activity .

N~+离子引起的黑麦染色体易位

Chromosome Translocation in Rye Induced by Nitrogen Ion Beam Irradiation

染色体易位是常见的染色体结构异常。

Chromosomal translocation is a kind of common chromosomal abnormality .

普通小麦染色体易位系端体测定的细胞学分析

Cytological analysis of translocations in common wheat with Chinese spring double ditelosomics