喹诺酮类抗菌药

结果各类喹诺酮类抗菌药具有不同的Rf值，能较好的进行区别。

RESULTS Different quinolones antibiotics had different Rf .

氟喹诺酮类（FQs）药物是第三代新型含氟的喹诺酮类抗菌药，抗菌谱广，抗菌活性强，在临床上被广泛应用。

Fluoroquinolones , a new type quinolones antibacterial agents with fluorin , are extensively used in the clinics because of its wide antibacterial spectrum and strong antibacterial activity .

喹诺酮类抗菌药不良反应的监测与分析

Analysis and Supervision of the Adverse Effects of Antibiotic Drug 4-Quinolones

我院128例喹诺酮类抗菌药不良反应分析

Analysis of 128 Cases of ADRs Induced by Quinolones in our Hospital

一般认为，喹诺酮类抗菌药通过结合细菌Ⅱ类拓扑异构酶，干扰细菌复制，而发挥抑菌作用。

Generally , Quinolones disturb bacterial DNA replication by binding topoisomerase type ⅱ .

喹诺酮类抗菌药耐药机制研究进展

Advancement of research on the mechanism of quinolone resistance

大肠埃希菌临床分离株对喹诺酮类抗菌药的质粒介导耐药

Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli

食品中喹诺酮类抗菌药的分析方法比较研究

Comparative of Analysis Methods for Quinolones Antibacterials in Food

地高辛与喹诺酮类抗菌药相互作用的研究进展

Advances in Research on Interaction between Digoxin and Quinolones

新喹诺酮类抗菌药合成路线概述

A survey of synthetic routes for new antibacterial quinolones

细菌对喹诺酮类抗菌药的分子耐药机制

Molecular Mechanisms of Resistance to Quinolones in Bacteria

喹诺酮类抗菌药的快速薄层色谱鉴别

Qualitative analysis of quinolones antibiotics by rapid TLC

目的快速鉴别喹诺酮类抗菌药。

OBJECTIVE To rapidly discriminate quinolones antibiotics .

喹诺酮类抗菌药在泌尿生殖系感染中的应用

Rational use of quinolones in urogenital infections

喹诺酮类抗菌药的应用和进展

Application and Development of Quinolones drugs

结论：克林沙星体内体外的抗菌活性较环丙沙星为优，是一个广谱高效的新喹诺酮类抗菌药。

CONCLUSIONS : The in vivo and in vitro activity of clinafloxacin is higher than ciprofloxacin .

目的合成喹诺酮类抗菌药中间体四氟邻苯二甲酸，并改进工艺，使之适用于工业化生产。

Objective To improve the synthesis of tetrafluorophthalic acid as an intermediate in preparing quinolone antibacterials .

喹诺酮类抗菌药在感染病治疗中的适应证及其合理应用：专家共识

The indications and rational use of quinolones in the treatment of infectious diseases : a consensus

2002-2004年医院喹诺酮类抗菌药应用调查

Analysis of the Application of Quinolones Antibacterial in our Hospital from 2002 to 2004 The Antimicrobial Drugs

分析临床常见病原菌对环丙沙星耐药性趋势，为临床合理应用喹诺酮类抗菌药提供依据。

Objective : To investigate the resistance tendency of ciprofloxacin to clinical common pathogenic bacteria for clinical usage of quinolones .

而在寻找新的喹诺酮类抗菌药的过程中发现有几个6位脱氟喹诺酮化合物较6位氟取代化合物有更强的抗菌活性，而且毒性更低。

In the search for new antibacterial agents , some of 6 des fluoro quinolone compounds were found more active in antibacterial effects and less toxicity than the corresponding 6 fluoro compounds .