同义突变
- synonymous mutation;samesense mutation
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其中位点一还未见报道,位点二的同义突变已有报道,但1692位点C到T的核苷酸突变并没有得到鉴定。
The synonymous mutation of the second site had been reported but the nucleotide substitution , dC → dT , had not been identified before .
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位于编码区的5个SNPs中,F216L、D374Y、I474V和E670G为错义突变,V460V为同义突变。
Among the five SNPs in the coding region , four are non-synonymous mutations and one is a synonymous mutation .
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核苷酸比对分析发现,NAC基因的变异主要发生在内含子区域,少数发生在编码氨基酸的密码子的第三位,属于同义突变范畴。
Nucleotide comparison analysis , NAC gene mutation occurred in intron regions , a few mutation is in the third site of codon , belonging to synonymous mutation .
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另对该基因在4个陆地棉高强纤维品系间的SNPs位点进行了分析,发现编码区的SNPs位点中存在非同义突变,可能与陆地棉纤维品质等表型相关。
In the accessions of upland cotton ( G. hirsutum ) with high fiber quality , the coding region SNPs with non-synonymous substitute were found , which may have phenotype effect .
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结果52例Rb肿瘤中除可见多态性、同义突变及内含子序列的变异外,未检出p53基因有真正的点突变。
Results Only did the polymorphisms , silent mutations and variants in intron have been shown in p53 gene , no real p53 gene mutation was found in retinoblastoma no matter the tumor carried Rb gene mutation or not .
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仅1例鼻咽癌为EB病毒LMP1WtXhoI/BamHIF,基因序列分析(LMP1第3外显子)发现也有7个碱基替换(其中5个为错义突变和2个为同义突变)。
In the NPC tissue ( 1 case only ) showing the prototype of Wt-XhoI / BamHI f , there were several base substitutions , including 5 missense mutations and 2 silent mutations present in LMP1 exon 3 , on DNA sequencing .
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结果有6例患者在第4外显子上检测到密码子277位点CTG→CTA的置换,导致亮氨酸的同义突变(L277L),属于单核苷酸多态性,发生率为8%(6/75)。
In result , A G → A transition in codon 277 was observed in exon 4 in six patients . This variation leads to a nonsense mutation ( L277L ) and is a previously described polymorphism , the rate of variation is 8 % ( 6 / 75 ) .
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同义突变13个,错义突变23个。
13 sites of synonymous mutation and 23 sites of missense mutation .
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此突变没有引起氨基酸的变化,为同义突变。
The motion not caused amino acid change , this is a Synonymous mutation . 2 .
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突变类型为4个错义突变、1个同义突变和1个非编码区突变;
The mutation types involve in 4 missense , 1 silent , and 1 non-coding area mutations .
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经测序和序列比对表明,该位点T188C(NC006088)是同义突变,没有引起氨基酸序列的变化。
The site is synonymous mutation by sequencing and sequence alignment that had not caused changes of amino acid sequence .
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共有11个突变位点,其中9个非同义突变位点,2个同义突变位点。
11 nucleotide mutation sites were discovered in the 82 M genes , 9 of which were nonsynonymous mutation and 2 synonymous mutation .
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与CV777及Br1/87核苷酸序列以及氨基酸遗传衍化关系分析显示,PEDV-QH株M基因的变异主要属于同义突变。
Sequences of nucleotides and amino acids correspondingly genetic derivation analysis showed that the mutation of M gene was belong to synonymous mutation mainly .
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结果96例中有14例发现了8种突变,5种错义突变,1种同义突变,1种无义突变,1种移码突变。
Results 8 mutations were detected from 14 cases , including 5 missense mutations , 1 synonymous mutation , 1 nonsense mutation and 1 frameshift mutation .
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红腺忍冬在多个位点上都发生了碱基突变,但其中有三个位点是错义突变,另外两个位点则是同义突变,没有引起氨基酸的改变。
Mutation happened in multiple sites of Red glandular honeysuckle , there are there missense mutations , the other two are same sense mutations without changes of amino acids .
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9例为点突变,其中错义突变4例、无义突变2例、同义突变3例,其余2例为碱基插入和缺失导致的移码突变。
There were 9 point mutations , including 4 missense mutations , 2 nonsense mutations , 3 silent mutations . The other 2 cases were frameshift mutations due to base insertion and deletion .
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撇开这一点不说,选择理论还能在解释基因序列和同义突变等新名词方面发挥作用,其影响范围之大,实在令人惊讶。
Despite our awareness of the wide reach of selection as an evolutionary force , its expanding sphere of influence for example , on gene order or synonymous mutations continues to surprise us .