制霉菌素

结论目前口腔假丝酵母菌感染患者口内菌株的耐药现象并不突出，白色假丝酵母菌对氟康唑、酮康唑、制霉菌素的敏感率均较高；

Conclusion At present , the resistance of Saccharomyces in patients with oral fungal infection is not significant , most Saccharomyces albicans are sensitive to fluconazole , ketoconazole and nystatin .

两性霉素B和制霉菌素、酮康唑和克霉唑都是已知的作用机制类似的抗真菌药物。

Amphotericin B and nystatin , ketoconazole and clotrimazole have been known to have similar antifungal mechanism respectively .

体外药敏试验显示对伊曲康唑、两性霉素B、制霉菌素高度敏感，酮康唑、克霉唑低度敏感，氟康唑耐药。

The drug sensitive test in vitro indicated that itraconazole , amphotericin B and nystatin were highly sensitive , ketoconazole and clotrimazole were low sensitive , fluconazole was resistant .

药敏试验以制霉菌素和两性霉素B最为敏感，抑菌质量浓度为6.0~24μg/mL；

Medicine sensitivity examination also showed nystatin and amphotericin B were most sensitive at inhibitory concentration of 6.0-24 μ g / mL , and KI and 5-flucytosin were the second sensitive .

体外药敏分析显示：对各种念珠菌的总体敏感率大于90%的抗真菌药物有制霉菌素（94.4%）、伊曲康唑（93.8%）、两性霉素B（93.8%）、5-氟胞嘧啶（91.9）。

The total percentage of susceptibility of Monilia to 5-fluorocytosine , amphotericin B , nystatin and itraconazole were 91.9 % , 93.8 % , 94.4 % and 93.8 % , respectively .

结果：检测出的念珠菌对特比萘芬耐药，对氟康唑、酮康唑、咪康唑、克霉唑中度敏感，对制霉菌素、伊曲康唑、两性霉素B、氟胞嘧啶高度敏感。

Result : Candida species are resistant to terbinafine , medium susceptible to fluconazole 、 ketoconazole 、 miconazole and clotrimazole , high susceptible to nystatin 、 itraconazole 、 amphotericin B and flucytosine .

另一组口服制霉菌素10万U～15万U/（kg·d），分3次。

Another group took Nystatin at dose of 100 ~ 150 thousand unit / ( kg · d ), three times a day for oral .

制霉菌素局部治疗口腔念珠菌病有效率为87.10%，存在少数MIC值与临床疗效结果不一的病例。

The effectiveness of nystatin was 87.10 % , and there were a few cases which MIC differs from the clinical effect .

结果：念珠菌对国产氟康唑的敏感率及治疗有效率均达97%，与进口氟康唑无差异，P＞0.05，2药治疗有效率均非常明显优于制霉菌素（P＜0.01）。

RESULTS : The effective rate of the domestic fluconazole reached 97 % , showing no difference from that of imported fluconazole ( P > 0.05 ) and was superior to that of nystatin group ( P < 0.01 ) .

真菌对5-fu、伊曲康唑、氟康唑多数存在明显耐药，对两性霉素、制霉菌素绝大多数真菌都敏感。

Fungi on the 5-fu , itraconazole , fluconazole and most obvious resistance to amphotericin , nystatin most fungi are sensitive . Conclusion : 1 .

激活AMPA受体抑制大鼠骶髓后连合核神经元NMDA反应&制霉菌素穿孔法膜片钳研究

Suppression of NMDA response in rat sacral dorsal commissural neurons by AMPA receptor activation : a study by the nystatin perforated patch technique

并对克霉唑乳酸配方阴道栓和制霉菌素治疗RVVC的疗效进行观察。

The efficacy of clotrimazole vaginal suppositories and nyspapinum in treating RVVC was observed .

论文获得以下主要研究结果：1.采用紫外线诱变处理EM菌和CL菌，用含制霉菌素和放线菌酮的抗性培养基平板筛选获得具有抗生素抗性的突变菌株。

The major results of the experiment showed as follows : 1 . The strains of EM and CL with antibiotic resistance were obtained by UV-treatment on conidia of EM and CL and screen in Nystatin and Cycloheximide media .

采用制霉菌素穿孔膜片箝技术，研究了P物质（SubstanceP，SP）对急性分离的大鼠骶髓后连合核神经元士的宁敏感性甘氨酸（glycine，Gly）反应的调控作用。

The modulatory effect of substance P ( SP ) on strychnine sensitive glycine ( Gly ) response was examined in neurons acutely dissociated from the rat sacral dorsal commissural nucleus ( SDCN ) using nystatin perforated patch recording configuration under voltage clamp conditions .

用制霉菌素穿孔膜片钳方法研究5－HT和NA对急性分离的大鼠骶髓后连合核神经元甘氨酸门控氯离子通道电流（IGly）的调控作用及其胞内机制。

The effects of 5 HT and NA on glycine gated Cl - channel currents ( I Gly ) and its intracellular mechanisms were investigated in acutely dissociated rat sacral dorsal commissural neurons by using nystatin perforated patch clamp recording .

高效液相色谱法研究国内外制霉菌素的组成

Studies on the composition of nystatin by high performance liquid chromatography

制霉菌素抗性筛选高活性苎麻脱胶菌诱变菌株

Mutation Breeding of Nystatin Resistant Microorganism with High Ramie Degumming Activity

国产制霉菌素主要组分的抗真菌活性

Antifungal activities of the major compositions of nystatin of China

开塞露联合制霉菌素治疗口腔霉菌感染

Glycerine enema combined with nystatin to treat patients with oral cavity fungus infection

甘油合用制霉菌素治疗口腔真菌感染的观察与护理

Observation and Nursing on Treatment of Oral Cavity Fungus Infection by Glycerin plus Anticandine

制霉菌素甘油预防口腔真菌感染的临床观察

Prevention of Oral Cavity Fungal Infection by Nystatin with Glycerol : A Clinical Observation

制霉菌素口腔黏膜给药致手足口病婴儿过敏性休克

Anaphylactic shock after applying nystatin to oral mucosa in an infant with hand-foot-mouth disease

制霉菌素甘油联合碳酸氢钠预防口腔霉菌感染注射用硫酸培普利欧霉素

Prevention of Oral Fungal Infection by Using Nystatin Glycerine and Sodium Bicarbonate in Combination

复方制霉菌素胶囊的制备与临床应用

Preparation and Clinical Application of Compound Nystatin Capsules

它具有灰黄霉素、制霉菌素、青霉索三药的抗菌谱。

It has griseofulvin , nystatin , penicillin antibacterial spectrum of cable three drugs .

地衣芽孢杆菌胶囊联合制霉菌素治疗儿童真菌性肠炎疗效观察

Observation on Curative Effects of Entrocoordinatibiogen / Anticandine Combination in Treatment of Fungal Enteritis in Children

制霉菌素片和达克宁（咪康唑）栓治疗复发性阴道念珠菌病疗效观察

An efficacy study of miconazole and nystatin tablets on treatment of patients with recurrent vulvovaginal candidiasis

已查明制霉菌素在肠道内可抑制菌丛类酵母菌的生长。

Nystain has been found to inhibit the growth of yeast like flora in the intestinal tract .

结论炉甘石制霉菌素洗剂抗炎作用明显，临床应用前景广阔。

Conclusion : Calamine nysfungin lotion possesses a certain therapeutic effect , with broad application prospect in clinic .

方法：制霉菌素打孔的膜片箝全细胞记录。

METHODS : Using a new patch-clamp whole-cell recording technic , namely nystatin-perforated whole-cell configuration under voltage-clamp mode .