代谢应激
- 网络metabolic stress;Catabolic stress
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然后考察了CP的蛋白质组表达谱,共鉴定231种非冗余蛋白质,主要是结合蛋白、转运蛋白与骨架分子,它们主要参与细胞过程、代谢以及应激反应。
A total of 231 non-redundant proteins identified , mainly are binding proteins , transfer proteins with molecular skeleton , which mainly involved in cellular processes , metabolism and stress response .
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Egr-1作为一种早期生长反应因子,在低氧诱导下有表达升高的现象,同时与短期低氧诱导的代谢性应激和细胞骨架重塑有关。
As an early growth response factor , there is elevated Egr-1 expression in hypoxic enviroment and increased cytoskeletal remodeling under acute hypoxic stress .
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结论Leptin可作为评价肥胖男性儿童内分泌功能的一项指标,Leptin与胰岛素、皮质醇、性激素等可能存在相互作用,对机体发育、能量代谢、应激反应等方面有所影响。
Conclusion Serum leptin level may be of a marker to evaluate the endocrinal function in obesity boys and interacts with insulin , corticoids and sex steroids . So it has influence on development of body , energy metabolism and stress reaction .
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并且作为代谢性应激源,2-DG无论用于动物还是人类都是安全有效的。
And as a metabolic stressor , 2-DG is innocuous enough to be used in research on both animals and humans , Mark added .
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利用Maldi-Tof-MS和LTQ技术进行鉴定,共鉴定出了40个差异表达蛋白质,这些差异表达蛋白质主要参与代谢、应激、生物调节等生物进程和催化活性、分子结合等分子功能。
40 differential proteins identified by Maldi-Tof-MS or LTQ were involved in biological process such as metabolic process , biological regulation , response to stimulus , signaling and molecular function such as catalytic activity , binding .
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与泌乳中、后期奶牛相比,泌乳前期奶牛的生产性能和机体代谢受热应激的影响更大。
Compared with the middle and late lactation cows , the effect of heat stress on performance and metabolism in early lactation cows were greater .
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研究者发现这些代谢性应激会产生更多的象神经酰胺一样特殊的脂肪。
The researchers found that these metabolic stresses lead to an upswing in production of a particular kind of fat molecule , known as ceramide .
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ERp在调节血脂代谢、抗氧化应激损伤、改善血管内皮功能、抑制动脉粥样斑块形成、舒缩血管、减少心脏缺血再灌注损伤等方面起重要作用。
ER β play an important role in many aspects such as regulate lipid metabolism , anti-oxidative stress injury , improve endothelial function , inhibit the formation of arterial plaque , modulate relaxation and contraction of blood vessels and reduce cardiac ischemia-reperfusion injury .
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另外,STITCH同样成功地应用于本实验的研究,所得的STITCH网络也被细分为一些小功能网络,包括能量代谢、氧化应激、基因转录调控以及卵黄蛋白原家族间相互作用等。
Besides , the STITCH network also was successfully applied in the BPA-exposed experiment and the whole network also could be divided into some small functional networks including energy metabolism , oxidative stress , regulation of gene transcription and the vitellogenins interaction network .
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气虚血瘀大鼠模型糖、脂代谢及氧化应激反应研究
Glucose and lipid metabolism and oxidative stress reaction in rat model of qi-deficiency and blood-stasis syndrome
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结论伤后早期肠道营养对调节代谢、减轻应激的作用明显优于早期静脉营养。
Conclusions The early enteral nutrition is more effective in reducing hypermetabolism response than the early parenteral nutrition .
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不同麻醉方法下食管手术病人围术期红细胞糖代谢和氧化应激反应的变化
Changes of the erythrocyte glucose metabolism and oxidative stress responses in patients undergoing esophageal surgery under different anesthetic techniques
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卡维地洛对胆汁淤积性肝纤维化大鼠肝组织胶原代谢及氧化应激的影响
Effects of Carvedilol on Collagen Metabolism and Oxidative Stress in Liver Tissues of Rats with Hepatic Fibrosis Induced by Bile Duct Ligation
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伴随着脂代谢、氧化应激和抗氧化系统的紊乱,机体铁代谢状况也发生异常。
The status of body iron metabolism is changed following the disorders of lipid metabolism , oxidative stress and antioxidant defense system .
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因此,渐进性神经退化性疾病很可能由于能量代谢和氧化应激循环过程受损而导致。
The age related onset and progressive course of these neurodegenerative diseases may be due to a cycle process between impaired energy metabolism and oxidative stresses .
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机体代谢紊乱引起氧化应激,最终导致活性羰基化合物在生物体内大量增加,导致羰基应激。羰基应激促进体内糖基化终末产物(AGEs)和脂氧化终末产物(ALEs)的大量生成和蓄积。
Because metabolic disturbance causes oxidative stress , reactive carbonyl compounds increase largely in bio-system and at last carbonyl stress appears .
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说明在T2DM发病过程中,脂代谢系统、氧化应激和抗氧化系统紊乱起着重要作用。
These illustrate that the disorders of lipid metabolism , oxidative stress and antioxidant defense system play an important role in diabetes . 4 .
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通过对差异蛋白的功能分析,揭示了双丹方通过改善能量代谢、对抗氧化应激等途径抗急性心肌缺血的作用机制。
Functional analysis of the differentially expressed proteins suggested that SDD diminished ischemic-induced damage through promoting myocardial energy status and reducing oxidative stress . 4 .
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各组织中尿素氮的代谢平衡在长期应激时趋于稳定,但这种稳定是建立在较高水平基础上。
The metabolic balance of the creatinine and urea nitrogen tend to be stable in the long-term strere , but the stabilization is in a high level .
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脂质代谢异常、氧应激反应、瘦素、脂联素等与胰岛素抵抗的发生有相互作用,也影响着非酒精性脂肪肝病的发生发展。
It has been shown that lipid metabolic disorder , oxidative stress , leptin , and adiponectin etc are interrelated with insulin resistance and contribute to the development of non-alcoholic fatty liver .
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充血性心力衰竭的多种发病机制如兴奋&收缩偶联异常、钙离子代谢紊乱、氧化应激及细胞凋亡等,都与心肌细胞能量代谢障碍有关联。
The mechanism of heart failure involves many factors , such as the abnormality of exciting-systole coupling , calcium metablism disorder , increasing of oxidative stress and cell apoptosis . They all related to energy metablism disorder of cardiomyocyte in the end .
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结论:腓肠肌和心肌中的NO代谢、GSH代谢及氧化应激水平对长期耐力运动的适应性反应存在差异;
Conclusion : The NO , GSH and oxidative stress have a different adaptive response to the longterm endurance exercise between in the cardiac muscle and in the GAST .
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为了消除这种不利的影响,细胞需要以一种适当的方式来调节一系列的代谢反应,使得细胞的代谢反应网络能在一个整体的水平上产生相应的代谢应激。
To antagonize such effects , the cell needs to regulate a range of metabolic reactions in a coordinated way , so that coherent metabolic responses are generated by the cellular metabolic reaction network as a whole .