黄连解毒汤

目的对黄连解毒汤的组分进行组合，探索不同药物组合的中药水提液在1万分子量的PS膜分离过程中的微观表现。

OBJECTIVE To explore into the microscopic behavior of different combinations of water extract of Huanglian Jiedu Decoction in the separation process using .

小鼠ig黄连解毒汤及其单味药所得含药血清对MDA生成呈时间和剂量依赖性。

The obtained serum after ig HJD and its single components to mice may inhibit MDA formation in a dose - and time-dependent manner .

方法：以季铵总碱的含量为指标，应用L9（34）正交试验设计筛选黄连解毒汤中黄连黄柏的最佳提取工艺条件。

Method : The optimum extraction conditions were investigated by the orthogonal design and in berberine as the content index .

黄连解毒汤可有效降低血脂水平，增强EPCs增殖能力、粘附能力、迁移能力、管状结构形成能力。

HJD could effectively reduce the blood lipid level and enhance the proliferation , adhesion , migration , tubular structure formation ability of EPCs . 3 .

黄连解毒汤对胰岛素抵抗大鼠骨骼肌IRS-1表达及酪氨酸磷酸化水平的影响

Effects of Huanglian Jiedu Decoction on IRS-1 Expression and Tyrosine Phosphorylation Level in Skeletal Muscles of the Rats with Insulin Resistance

黄连解毒汤可能通过降低血脂水平，增强EPCs功能及抑制炎症反应来延缓热毒所致AS的形成过程。

HJD could reduce blood lipid level , strengthen the function of EPCs and inhibit the inflammatory response to delay the formation of atherosclerosis which was caused by toxic heat .

方法：观察黄连解毒汤对实验性2型糖尿病大鼠治疗前后血糖（FBG）、胰岛素（FINS）、血清白介素-4（IL-4）和白介素-10（IL-10）等指标的影响。

Method : The effect of HJD on fasting blood glucose ( FBG ), fasting insulin ( FINS ), interleukin-4 ( IL-4 ) and interleukin-10 ( IL-10 ) in type 2 diabetic rats were observed .

加味黄连解毒汤很有可能对炎症通路及炎症介质进行有效调控，以期在防治MODS发生和降低死亡率将发挥独到的作用。

Jiawei Huanglian Jiedu Decoction is likely to regulate inflammatory mediators in inflammatory pathways effectively which to play a unique role in prevention together with cure of MODS , and reducing its mortalityObjective : 1 .

结论：黄连解毒汤及其主要有效成分小檗碱具有提高2型糖尿病大鼠血清抗炎细胞因子IL-4和IL-10水平的作用，改善其慢性炎性反应和胰岛素抵抗。

Conclusion : HJD and its main effective component Berberine could increase the levels of IL-4 and IL-10 , and alleviate chronic inflammatory reaction in the diabetic pathogenic mechanism , through which they might improve insulin resistance .

结果观察到给予黄连解毒汤治疗的实验性2型糖尿病大鼠，其血清中FBG、IL-1β、IL-6、TNF-α、CRP的水平比模型对照组明显降低，显著OGTT改善。

Results : The levels of FBG 、 FINS 、 IL-1 β , IL-6 , TNF - α in the rats treated by Huanglian Jiedu decoction were significantly decreased and OGTT was obviously improved compared with those in control group .

目的：观察黄连解毒汤有效部位（HJDAF）对培养皮层神经细胞一氧化氮损伤的保护作用。

AIM : To investigate protective effects of Huanglian Jiedu Decoction active fraction ( HJDAF ) on NO-induced cerebral cortical neuron injury .

目的：1、观察加味黄连解毒汤对MODS患者外周血单核细胞TLR4表达的影响，从而进一步了解加味黄连解毒汤通过调控TLR4对MODS的作用机制。

To observe effect of Jiawei Huanglian Jiedu Decoction on expression of Toll-like receptor 4 from mononuclear cells in peripheral blood of MODS patients , which is in order to learn more about effect mechanism of Jiawei Huanglian Jiedu Decoction on MODS by regulating Toll-like receptor 4 . 2 .

结论：黄连解毒汤提高胰岛素抵抗大鼠骨骼肌组织IRS-1蛋白表达和酪氨酸磷酸化水平，这可能是其降血糖并改善组织胰岛素敏感性的机制之一。

Conclusion Huanglian Jiedu Decoction improves IRS-1 protein expression and tyrosine phosphorylation level in the skeletal muscle tissue of the rats with insulin resistance , which is possibly one of the mechanisms of decreasing blood sugar and improving sensitivity of insulin in tissues .

以血清药理学方法研究黄连解毒汤对小鼠的药效动力学

Pharmacodynamic study on Huanglian Jiedu Decoction in mice by serum pharmacological method

复方黄连解毒汤治疗多器官功能障碍综合征的疗效评价

Therapeutic Evaluation for the MODS Patients Treated with the Compound of Huang-Lian-Jie-Du-Tang

黄连解毒汤及其提取部位益智作用

The Improving Effect of Decoction Decoction of Coptis and Its Extract on intelligence

目的：观察黄连解毒汤的降血糖作用。

Objective : To observe the reducing blood sugar effects of HLJD Decoction .

前言：目的：选择半仿生法提取黄连解毒汤的最佳药材组合方式。

Object : To select the optimum extracting mode of Huanglian Jiedu Decoction .

黄连解毒汤有效部位对一氧化氮诱导大鼠皮层神经元损伤的保护作用

Protective Effect of Huanglian Jiedu Decoction Active Fraction on NO-induced Cerebral Cortical Neuron Injury

黄连解毒汤对小鼠急性脑缺血、缺氧的影响

Effects of the Huanglian Jiedu Decoction on acute cerebral ischemia and hypoxia in mice

结论：对黄连解毒汤生产有参考价值。

Conclusion : This result is the reference value in the production of CTRD .

黄连解毒汤的抗血栓作用研究

Research on antithrombotic effects of Huanglian Jiedu Decoction

黄连解毒汤体外抗真菌活性及其与西药的联合药敏试验研究

In Vitro Anti-fungal Effect of Coptidis Decoction for Detoxification or Combined with Western Medcine

黄连解毒汤对小鼠脑缺血慢性神经损伤的保护作用

Protective effects of Huanglian-Jiedu-Tang on chronic brain injury after focal cerebral ischemia in mice

方法：对30例舌癌患者运用加味黄连解毒汤治疗。

Method : 30 cases of tongue cancer were treated with Jiawei Huanglian Jiedu Decoction .

黄连解毒汤传统汤剂与配方颗粒汤剂主要活性成分含量比较

Comparison of the Main Components between Traditional Decoction and Dispensing Granule Decoction of Huanglian Jiedu Decoction

黄连解毒汤吸收入血有效成分的筛选及生物学作用研究

The Selecting and the Studying of Effective Components Absorbed into Blood from Huang Lian Jie Du Tang

黄连解毒汤加味合并氯氮平治疗精神分裂症兴奋激越症状患者80例临床观察

Treatment for the Excitation and Agitation of 80 Schizophrenia Patients with Modified Huanglian Jiedu Decoction Combined with Clozapine

结果：用新法制备的黄连解毒汤的栀子甙含量比日本汉方制剂黄连解毒汤中的高。

Results : The new method preparing CTRD shows a higher content of Geniposide than the Japanese Kampo CTRD .

目的：观察黄连解毒汤交叉配伍对活性氧自由基的清除作用。

Objective : To observe the scavenging effects of Coptidis Toxin Resolving Decoction ( cross compatibility ) on oxygen free radicals .