血管生成抑制剂

内源性血管生成抑制剂可作为一种抑癌蛋白。

Endogenous angiogenesis inhibitors act as tumor suppressor proteins .

此外，一些血管生成抑制剂已被FDA批准作为治疗癌症或眼内新生血管性疾病。

In addition , several angiogenesis inhibitors have been approved by the FDA as therapy for cancer or intraocular neovascular disorders .

目的采用Lewis肺癌来验证血管生成抑制剂TNP－470对肿瘤生长和转移的抑制作用。

Objective The inhibition effect of angiogenesis inhibitor TNP 470 on tumor growth and metastasis was studied using Lewis lung carcinoma .

目前，肿瘤化疗进入平台期，寻找有效的肿瘤血管生成抑制剂（TAI）已成为抗肿瘤新药研究的一个热点。

Now , chemotherapy of tumor enter in plateau . Find out effective tumor angiogenic inhibitor has become a hot point in researching new drug for tumor .

血管生成抑制剂TNP-470抑制血管瘤血管内皮细胞增殖的体外实验研究

Angiogenesis inhibitor TNP-470 inhibits the growth of vascular endothelium from hemangioma in vitro

目的：采用鸡胚绒毛尿囊膜（ChickChorioallantoicmembrane，CAM）法从26种活血化瘀中药中初筛血管生成抑制剂。

Objective : To screen angiogenesis inhibitor from 26 drugs for promoting blood circulation and removing blood stasis through chick chorioallantoic membrane ( CAM ) model in vivo .

血管生成抑制剂TNP-470抑制Walker256肉瘤生长的实验研究

An Experimental Study of Angiogenesis inhibitor TNP-470 Inhibiting the Tumor Growth of Walker 256 Carcinoma

原核表达活性内源性血管生成抑制剂canstatin蛋白

Prokaryotic expression of an active endogenous inhibitor of angiogenesis-canstatin

血管生成抑制剂去甲二氢愈创木酸（NDGA）对大鼠胚胎及卵巢功能影响的初步研究

Effect of Angiogenesis Inhibitor Nordihydroguaiaretic Acid on Embryo and Ovarian Function in Rat

血管生成抑制剂TNP-470与细胞毒药物Gemcitabine的抗胰腺癌生长和转移作用的比较研究

Comparative study of the inhibitory effect of angiogenesis inhibitor , TNP-470 and Gemcitabine on the growth and metastasis of pancreatic carcinoma

目的观察血管生成抑制剂TNP-470对人涎腺腺样囊性癌肺转移的抑制作用。

Objective To study the effect of angiogenesis inhibitor TNP-470 on the metastasis of salivary adenoid cystic carcinoma in vivo .

血管生成抑制剂YH-16联合化疗栓塞抑制大鼠移植型肝癌的研究

Inhibitory Effect of Angiogenesis Inhibitor YH-16 in Combination with Chemoembolization on Rat 's Transplanted Hepatoma

肿瘤血管生成抑制剂CA-4的合成

Synthesis of tumour vascular inhibitor CA-4

新型肿瘤血管生成抑制剂hexastatin的研究进展

Advances of a new inhibitor of tumor angiogenesis : hexastatin

血管生成抑制剂TNP-470对人恶性胶质瘤细胞系SHG44及其移植瘤生长的影响

Inhibitory effects of angiogenesis inhibitor TNP-470 on growth of a human malignant glioma cell line SHG-44 and its xenografted tumor

重组血管生成抑制剂Ad-METH-1对增生性瘢痕作用的实验研究

The Effect of Recombination Angiogenesis Inhibitor Ad-METH-1 on Hypertrophic Scar

目的检测成纤维细胞生长因子（FGF）对内皮细胞（EC）增生及对血管生成抑制剂TNP-470和地塞米松（Dex）作用的影响，探讨FGF促进内皮细胞增生的可能机制。

Objective To determine the effect of fibroblast growth factor ( FGF ) on endothelia cell ( EC ) proliferation in vitro , TNP-470 and dexamethasone ( Dex ) and explore the possible mechanisms of FGF stimulating EC proliferation .

色素上皮衍生因子（PEDF）来源于人视网膜色素上皮细胞，是眼内有效的血管生成抑制剂，对保持正常眼组织透明无血管的状态有重要作用。

Pigment epithelium-derived factor ( PEDF ) secreted from human retinal epithelium cells is a potent angiogenic inhibitor in the mammalian eyes . By excluding aberrant blood vessels from ocular tissues , PEDF plays an important role to keep normal mammalian eyes with visual acuity .

CA-4不仅是一种针对微观蛋白的新式细胞毒类抗肿瘤物质，也是肿瘤血管生成抑制剂，而且对正常的脉管系统没有副作用。

CA-4 has been studied intensively because of its potent anti-cancer activity . CA-4 not only is a new cytotoxic agent ( target in tubulin protein ), but also is a tumor angiogenesis inhibitor and it is relatively inactive in normal tissues .

血管生成抑制剂治疗卵巢癌的研究进展

Progress of Angiogenesis Inhibitor in the treatment of Ovarian Cancer

血管生成抑制剂对肿瘤抑制作用的研究

Study of inhibition effect of angiogenic inhibitor to tumors

因此，探讨血管生成抑制剂对抑制肿瘤转移的作用，对肿瘤的治疗可能具有重要意义。

Therefore discussing angiogenesis inhibitors effect on neoplasm metastasis may direct clinical treatment .

血管生成抑制剂联合放射治疗大肠癌肝转移模型

Therapeutic Effect of Angiogenesis Inhibitor Combined with Radiotherapy on Liver Metastasis Model of Colon Cancer

该研究建议医生在临床使用血管生成抑制剂时需要监控患者的肾脏情况。

The results suggest that physicians should monitor patients'kidney health when prescribing this angiogenesis inhibitor .

原核表达融合型血管生成抑制剂Kringle5发酵条件的优化和初步纯化

Optimization of Batch Fermentation and Preliminary Purification for Fusion Angiogenesis Inhibitor Kringle 5 in Prokaryotic System

目的从中药中寻找新的血管生成抑制剂，并探讨其抑制新生血管生成的作用机理。

Objective To find new angiogenic inhibitors from TCM drugs and investigate their mechanisms of inhibiting angiogenesis .

因此，兼具传统细胞毒药物与新生血管生成抑制剂效果的多靶点药物具有潜在应用前景。

Hence , multi-target agents with rational combination of cytotoxic agents and angiogenesis inhibitor have potential application .

血管生成抑制剂烟曲霉素衍生物在介入治疗肝细胞癌实验中的应用

The application of TNP-470 as an antiangiogenesis drug in the experiment of interventional therapy of hepatocellular carcinoma

它的组成部分的一类药物称为血管生成抑制剂首创由已故医生犹大福克曼的波士顿儿童医院的。

It 's part of a class of drug known as angiogenesis inhibitors pioneered by the late Dr.

多种血管生成抑制剂已经在临床前期癌症模型中证实有效，并有几种临床证实有效。

Multiple angiogenesis inhibitors have been therapeutically validated in preclinical cancer models , and several in clinical trials .