黄芩甙

RP-HPLC法测定桂林西瓜霜喷剂中黄芩甙的含量

Determination of Baicalin in Guilin watermelon frost by RP-HPLC

结果表明，黄芩甙可显著减少再灌注性心律失常发生率，降低CPK活性和MDA含量，升高SOD和GSHpx活性。

The results showed that baicalin reduced frequency of arrhythmia , contents of CK and MDA , and increased activities of SOD and GSH PX .

黄芩甙对小鼠肝细胞色素P（450）及其亚家族的诱导

Effects of baicalin on liver microsomal cytochrome P_ ( 450 ) system

野黄芩甙元及其类似物对蛋白激酶C的抑制作用

Inhibition of protein kinase C by scutellarein and its analogues

黄芩甙和芸香甙对·OH的清除作用

The scavenging effects of baicalin and rutin on . Oh

无氧黄芩甙乙醇溶液辐解产物的HPLC分离

HPLC separation of radiolysis products of deaerated baicalin ethanolic solution

二阶导数光谱法测定羚羊清肺散中黄芩甙含量中药XRD二阶指纹图谱方法学研究

Methodology Research on XRD Second Derivative Fingerprint of Traditional Chinese Medicine

结果：野黄芩甙ip给药，对正常大鼠的体温无明显影响，用药前后体温变化差异无显著性（P＞0.05）。

Results : Before and after scutellarin was given to normal rats , there was no obvious difference in body temperature ( P > 0.05 ) .

方法：采用TLC法对处方中的大黄、盐酸小檗碱、黄芩甙等进行鉴别；

Methods : Applying the technique of TLC to identify Rhubarb , Berberine hydrochloride and Baicalin .

目的：观察黄芩甙（Baicalin，Bai）对2.2.15细胞分泌HBsAg和HBeAg的影响，探讨黄芩甙的体外抗HBV作用。

Objective : To evaluate the effect of baicalin on excreting HBsAg and HBeAg of 2.2.15 cells .

丹参素、黄芩甙等对大鼠腹腔巨噬细胞产生PGE2及TXB2的影响

Pharmacological Regulation of PGE_2 and TXB_2 Production by Rat Peritoneal Macrophages

野黄芩甙的解热作用持续4h。

Lts antipyretic effect lasted about 4 hours .

万氏牛黄清心丸中黄芩甙及小檗碱的高效液相色谱条件优化及分离测定无氧黄芩甙乙醇溶液辐解产物的HPLC分离

Optimization and Determination of Berberine and Baicalin in Wanshi Niuhuang Qingxin Wan by High Performance Liquid Chromatography HPLC SEPARATION OF RADIOLYSIS PRODUCTS OF DEAERATED BAICALIN ETHANOLIC SOLUTION

结果：黄芩甙能明显减轻脑水肿程度（P<0.01），降低脑组织铁含量和MDA浓度（P<0.01），提高SOD活性（P<0.01）。

Results : The baicalin could reduce the infective brain edema , and lower iron content , MDA level , and improve the activity of SOD .

结论（1）黄芩甙和奥曲肽对SAP肺损害均具有保护作用，其治疗机制可能与细胞凋亡有关。

Conclusions ( 1 ) Both Baicalin and Octreotide have protecting effect on SAP lung injury and their therapeutic mechanism is possibly related to apoptosis .

方法：采用均匀设计法，以黄芩甙含量为主要考察指标，对黄芩愈伤组织生长的MS培养基成分进行多因素多水平考察。

Methods : The components of MS medium for growth of callus were investigated from poly-factors and poly-levels by uniform design . Baicalin content was chosen as the main experiment index .

结果：复方黄芩甙制剂治疗后，小鼠淋巴结细胞和脾细胞CD3、CD8阳性细胞百分比升高；

Results : The percentage of CD3 and CD8 positive cells of LN and splenocyte in mice treated with Co-baicalin was significantly increased .

方法：采用TLC对感冒宁冲剂中大青叶、金银花、防风进行定性鉴别，利用紫外分光光度法对制剂中的黄芩甙进行含量测定。

Method : To apply TLC to Indigowood , Honeysuckle flower and Divaricate saposhnikovia root for qualitative identification , while UV spectrophotometer to Baicalin for content assaying .

探索反相HPLC分离黄芩甙乙醇溶液辐解产物，特别探讨了酸在淋洗液中的作用，及液塞对分离的影响。

The separation of radiolysis products of deaerated baicalin ethanolic solution by reverse HPLC was studied , especially , the functions of acid in eluents and the influence of solvent strength on separation were discussed .

以携带R质粒的痢疾杆菌F（13）株为靶细菌，以黄芩甙作为R质粒消除剂，进行R质粒体外消除试验。

The R plasmid curing experiment was performed in Shigella strain , F_ ( 13 ), which used as a target bacteria bearing R plasmid with Huangqin , a traditional chinese herb , as a elimination agent in vitro .

结果黄芩甙治疗组、奥曲肽治疗组12h生存率明显大于模型组，差异有显著性（P＜0.05）；

Results The 12h survival of model group was 66,67 % while those of Baicalin treatment group and Octreotide treatment groups were both 100 % , indicating a marked difference ( P < 0.05 ) .

结论：黄芩甙对细菌性脑膜炎具有一定的治疗作用，其机理可能与抑制体内TNF-α、IL-1、NO等炎症因子的过度释放有关。

Conclusion : Baicalin has some effect on treatment of bacterial meningitis , the treatment mechanism is inferred to restrain the excessive release of TNF - α, IL-1 , NO in the body .

目的观察黄芩甙和奥曲肽对重症急性胰腺炎（SAP）大鼠肺损害的影响，探讨两药对SAP的治疗作用与机制。

Objective To observe the influence of Baicalin and Octreotide on lung injury of rat with severe acute pancreatitis ( SAP ) and discuss the therapeutic effect and mechanism of the two medicines on SAP .

研究了碳源、肌醇、激素、水解酪蛋白（CH）和水解乳蛋白（LH）对悬浮系中黄芩甙含量的影响。

The effects of carbon source , inositol , plant hormone , casein hydrolysate ( CH ) and lactalbumin hydrolysate ( LH ) on baicalin content in cell suspension cultures were studied .

目的观察中波紫外线（UVB）辐射后成纤维细胞（FB）DNA光产物环丁烷嘧啶二聚体（CPDs）产生和清除情况及表没食子儿茶素没食子酸酯（EGCG）和黄芩甙的干预作用。

Objective To investigate the production and removal of cyclobutane pyrimidine dimers ( CPDs ) induced by UVB irradiation and intervention effect by epigallocatechingallate ( EGCG ) in human fibroblasts .

目的：探讨复方黄芩甙制剂（Co-baicalin）治疗实验性自身免疫性脑脊髓炎（EAE）的有效性及其作用机制。

Objective : To explore the therapeutic effects of co-baicalin on experimental autoimmune encephalomyelitis ( EAE ) and its mechanism .

目的探讨黄芩甙（BC）、川芎嗪（TMPZ）、甘露醇（MN）对兔百日咳菌液（PB）脑水肿的治疗作用及机理。

Objective To explore the mechanism and effect of baicalin ( BC ), tetramethy1pyrazine ( TMPZ ) and mannitol ( MN ) on infectious brain edema induced by pertussis bacilli ( PB ) in rabbits .

结果：在TLC色谱中均能检出大青叶、金银花、防风，含量限度黄芩甙不少于6.68mg/g。

Result : In TLC , Indigowood , Honeysuckle flower and Divaricate saposhnikovia root could be checked out , and Baicalin was more than 6.68mg/g .

大黄素、黄芩甙能上调RSV感染细胞TNF-a的mRNA的表达，其中大黄素不但能促进感染细胞凋亡，还可能存在干预RSV融合病变的作用。

Emodin and baicalin can up-regulate the expression of TNF-a mRNA in RSV infected cells , besides , emodin was able to enhance cell apoptosis in infected cells , and may interfere with cell fusion as well .

目的：探讨正常及肾盂肾炎大鼠肾脏表面活性蛋白A（SP-A）的表达变化及黄芩甙对SP-A表达的影响。

Objective To investigate the expression of surfactant protein A ( SP-A ) in normal kidney and E.coli-induced phynonephritic kidney , and observe the effect of baicalin on SP-A expression .